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肌肉松弛剂治疗急性下腰痛,不要看广告,得看疗效

2021-07-17 MedSci原创 MedSci原创

肌肉松弛剂的临床疗效和安全性存在相当大的不确定性。

腰痛是一个主要的全球公共卫生问题,给个人、医疗保健和社会带来负担,在过去30年中,腰痛一直是全球残疾的主要原因。下腰痛是全科医生就诊的常见原因,当患者经常服用止痛药以控制症状时。肌肉松弛剂,包括非苯二氮卓类解痉药和抗痉挛药,是治疗腰痛的第三大常用处方药。然而,对肌肉松弛剂的使用建议,国际腰痛临床实践指南之间存在冲突。例如,美国指南建议非苯二氮卓类解痉药作为治疗急性腰痛的首选药物,比利时指南不鼓励此类使用,而英国指南未提出建议。 为了探讨肌松药治疗腰背痛的有效性、可接受性和安全性。Aidan G Cashin等进行了随机对照试验的系统综述和荟萃分析。研究结果发表在BMJ杂志。 该研究的资料来源于medline,embase,cinahl,central, clinicaltrials.gov , clinicialtrialsregister.eu ,WHO ICTRP。 观察指标包括疼痛强度(0-100分量表)、残疾(0-100分量表)、可接受性(治疗期间因任何原因停用药物)和安全性(不良事件、严重不良事件,以及因不良事件退出试验的参与者人数)。 共有49个试验纳入,其中31项试验,6

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    2022-03-22 respect
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    2021-11-29 ms3000000834784203

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    2021-07-18 牧师与屠夫

    学习

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    2021-07-18 147fd2dfm17暂无昵称

    学习学习学习,学习学习学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2080270, encodeId=81f520802e071, content=<a href='/topic/show?id=1cc380996df' target=_blank style='color:#2F92EE;'>#肌肉松弛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80996, encryptionId=1cc380996df, topicName=肌肉松弛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b505306, createdName=医生2394, createdTime=Wed Aug 11 00:11:14 CST 2021, time=2021-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1746825, encodeId=ca7f1e46825c0, content=<a href='/topic/show?id=eaea2022574' target=_blank style='color:#2F92EE;'>#下腰痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20225, encryptionId=eaea2022574, topicName=下腰痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=54d235859840, createdName=respect, createdTime=Tue Mar 22 00:11:14 CST 2022, time=2022-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1075211, encodeId=afd710e5211eb, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=83125648445, createdName=ms3000000834784203, createdTime=Mon Nov 29 21:21:09 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000723, encodeId=1abf1000e23c3, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210718/00c6135c486d494ba3a6de6564321e4b/210f794fc7764c1fbd33f29779f68f37.jpg, createdBy=2ce95551880, createdName=牧师与屠夫, createdTime=Sun Jul 18 23:04:15 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000532, encodeId=3ac2100053288, content=学习学习学习,学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a6315259858, createdName=147fd2dfm17暂无昵称, createdTime=Sun Jul 18 09:40:02 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000504, encodeId=4361100050465, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210225/938039c6a8dd44da88f12057ac560714/12320b429ac14066810455a5a10e4aa9.jpg, createdBy=4dea2051957, createdName=189****1979, createdTime=Sun Jul 18 06:28:13 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000500, encodeId=b756100050012, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Sun Jul 18 01:19:07 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033037, encodeId=8f3b103303e18, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sun Jul 18 01:11:14 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000482, encodeId=efe51000482d1, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c1fe5546632, createdName=ms5000001190825271, createdTime=Sat Jul 17 23:29:09 CST 2021, time=2021-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000479, encodeId=a1e410004e96e, content=腰痛, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87f65551378, createdName=ms9000001907673449, createdTime=Sat Jul 17 23:20:35 CST 2021, time=2021-07-17, status=1, ipAttribution=)]
    2021-07-18 189****1979

    学习了

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2080270, encodeId=81f520802e071, content=<a href='/topic/show?id=1cc380996df' target=_blank style='color:#2F92EE;'>#肌肉松弛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80996, encryptionId=1cc380996df, topicName=肌肉松弛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b505306, createdName=医生2394, createdTime=Wed Aug 11 00:11:14 CST 2021, time=2021-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1746825, encodeId=ca7f1e46825c0, content=<a href='/topic/show?id=eaea2022574' target=_blank style='color:#2F92EE;'>#下腰痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20225, encryptionId=eaea2022574, topicName=下腰痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=54d235859840, createdName=respect, createdTime=Tue Mar 22 00:11:14 CST 2022, time=2022-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1075211, encodeId=afd710e5211eb, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=83125648445, createdName=ms3000000834784203, createdTime=Mon Nov 29 21:21:09 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000723, encodeId=1abf1000e23c3, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210718/00c6135c486d494ba3a6de6564321e4b/210f794fc7764c1fbd33f29779f68f37.jpg, createdBy=2ce95551880, createdName=牧师与屠夫, createdTime=Sun Jul 18 23:04:15 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000532, encodeId=3ac2100053288, content=学习学习学习,学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a6315259858, createdName=147fd2dfm17暂无昵称, createdTime=Sun Jul 18 09:40:02 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000504, encodeId=4361100050465, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210225/938039c6a8dd44da88f12057ac560714/12320b429ac14066810455a5a10e4aa9.jpg, createdBy=4dea2051957, createdName=189****1979, createdTime=Sun Jul 18 06:28:13 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000500, encodeId=b756100050012, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dffa5465843, createdName=ms2000001361349190, createdTime=Sun Jul 18 01:19:07 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033037, encodeId=8f3b103303e18, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sun Jul 18 01:11:14 CST 2021, time=2021-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000482, encodeId=efe51000482d1, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c1fe5546632, createdName=ms5000001190825271, createdTime=Sat Jul 17 23:29:09 CST 2021, time=2021-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1000479, encodeId=a1e410004e96e, content=腰痛, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87f65551378, createdName=ms9000001907673449, createdTime=Sat Jul 17 23:20:35 CST 2021, time=2021-07-17, status=1, ipAttribution=)]
    2021-07-18 ms2000001361349190

    学习

    0

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    2021-07-18 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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    2021-07-17 ms5000001190825271

    学习学习

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    2021-07-17 ms9000001907673449

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