Baidu
map

Stroke: HAVOC评分对心房颤动风险预测能力有待确定

2020-02-19 国际循环 国际循环

近期,Stroke杂志发表研究,旨在评估HAVOC评分模型在隐源性栓塞性卒中患者外部队列的使用效果。

为预测卒中发作后患者的心房颤动风险,临床提出HAVOC(即高血压、年龄、瓣膜性心脏病、外周血管疾病、肥胖、充血性心力衰竭和冠状动脉疾病)评分模型。模型的区分度良好(曲线下面积0.77),只有2.5%的HAVOC评分属于低危(即0~4分)的患者确诊新发心房颤动。近期,Stroke杂志发表研究,旨在评估HAVOC评分模型在隐源性栓塞性卒中患者外部队列的使用效果。
 
以心房颤动-栓塞性卒中数据库为基础,研究人员评估HAVOC评分用于预测新发心房颤动的判别能力、校准值、特异性、阴性预测值和准确性。根据初始出版建议,患者HAVOC评分为0~4可视为低危人群。

研究共纳入658例隐源性栓塞性卒中患者(中位年龄67岁,44%为女性),HAVOC评分中位数为2(四分位数范围3),有540例(82%)患者的HAVOC评分为0~4分,118例(18%)患者的HAVOC评分≥5分,95例患者(14.4%)确诊新发心房颤动[28.8%的患者心房颤动评分≥5分,11.3%的患者心房颤动评分为0~4分(年龄和性别调整OR=2.29;95%CI:1.37~3.82)]。低危HAVOC评分对无新发心房颤动患者的预测特异性为88.7%。此外,低危HAVOC评分的阴性预测值为85.1%,准确率78.0%,曲线下面积68.7%(95%CI:62.1%~73.3%)。
 
在研究队列中,既往报道中关于“低危HAVOC评分的隐源性栓塞性卒中患者心房颤动风险较低”这一说法没有得到证实。在临床实践作为常规措施实施之前,HAVOC评分模型需进一步评估。

原始出处:
George Ntaios, Kalliopi Perlepe, et al. External Performance of the HAVOC Score for the Prediction of New Incident Atrial Fibrillation. Stroke. Originally published12 Dec 2019

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1694071, encodeId=575416940e1bf, content=<a href='/topic/show?id=a18d848571' target=_blank style='color:#2F92EE;'>#HAVOC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8485, encryptionId=a18d848571, topicName=HAVOC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=14d329554080, createdName=yuandd, createdTime=Fri Aug 07 05:38:00 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947892, encodeId=1c38194e892f1, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 04 11:38:00 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485974, encodeId=cf0914859e47f, content=<a href='/topic/show?id=2c62100911a3' target=_blank style='color:#2F92EE;'>#风险预测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100911, encryptionId=2c62100911a3, topicName=风险预测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e31a8064712, createdName=12498ebem21暂无昵称, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626931, encodeId=a5d71626931bf, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51017, encryptionId=986a5101e46, topicName=心房)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20ba21064884, createdName=sodoo, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031228, encodeId=96961031228af, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Feb 19 23:38:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
    2020-08-07 yuandd
  2. [GetPortalCommentsPageByObjectIdResponse(id=1694071, encodeId=575416940e1bf, content=<a href='/topic/show?id=a18d848571' target=_blank style='color:#2F92EE;'>#HAVOC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8485, encryptionId=a18d848571, topicName=HAVOC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=14d329554080, createdName=yuandd, createdTime=Fri Aug 07 05:38:00 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947892, encodeId=1c38194e892f1, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 04 11:38:00 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485974, encodeId=cf0914859e47f, content=<a href='/topic/show?id=2c62100911a3' target=_blank style='color:#2F92EE;'>#风险预测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100911, encryptionId=2c62100911a3, topicName=风险预测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e31a8064712, createdName=12498ebem21暂无昵称, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626931, encodeId=a5d71626931bf, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51017, encryptionId=986a5101e46, topicName=心房)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20ba21064884, createdName=sodoo, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031228, encodeId=96961031228af, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Feb 19 23:38:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1694071, encodeId=575416940e1bf, content=<a href='/topic/show?id=a18d848571' target=_blank style='color:#2F92EE;'>#HAVOC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8485, encryptionId=a18d848571, topicName=HAVOC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=14d329554080, createdName=yuandd, createdTime=Fri Aug 07 05:38:00 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947892, encodeId=1c38194e892f1, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 04 11:38:00 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485974, encodeId=cf0914859e47f, content=<a href='/topic/show?id=2c62100911a3' target=_blank style='color:#2F92EE;'>#风险预测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100911, encryptionId=2c62100911a3, topicName=风险预测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e31a8064712, createdName=12498ebem21暂无昵称, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626931, encodeId=a5d71626931bf, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51017, encryptionId=986a5101e46, topicName=心房)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20ba21064884, createdName=sodoo, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031228, encodeId=96961031228af, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Feb 19 23:38:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1694071, encodeId=575416940e1bf, content=<a href='/topic/show?id=a18d848571' target=_blank style='color:#2F92EE;'>#HAVOC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8485, encryptionId=a18d848571, topicName=HAVOC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=14d329554080, createdName=yuandd, createdTime=Fri Aug 07 05:38:00 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947892, encodeId=1c38194e892f1, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 04 11:38:00 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485974, encodeId=cf0914859e47f, content=<a href='/topic/show?id=2c62100911a3' target=_blank style='color:#2F92EE;'>#风险预测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100911, encryptionId=2c62100911a3, topicName=风险预测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e31a8064712, createdName=12498ebem21暂无昵称, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626931, encodeId=a5d71626931bf, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51017, encryptionId=986a5101e46, topicName=心房)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20ba21064884, createdName=sodoo, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031228, encodeId=96961031228af, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Feb 19 23:38:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
    2020-02-21 sodoo
  5. [GetPortalCommentsPageByObjectIdResponse(id=1694071, encodeId=575416940e1bf, content=<a href='/topic/show?id=a18d848571' target=_blank style='color:#2F92EE;'>#HAVOC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8485, encryptionId=a18d848571, topicName=HAVOC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=14d329554080, createdName=yuandd, createdTime=Fri Aug 07 05:38:00 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947892, encodeId=1c38194e892f1, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 04 11:38:00 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485974, encodeId=cf0914859e47f, content=<a href='/topic/show?id=2c62100911a3' target=_blank style='color:#2F92EE;'>#风险预测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100911, encryptionId=2c62100911a3, topicName=风险预测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e31a8064712, createdName=12498ebem21暂无昵称, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626931, encodeId=a5d71626931bf, content=<a href='/topic/show?id=986a5101e46' target=_blank style='color:#2F92EE;'>#心房#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51017, encryptionId=986a5101e46, topicName=心房)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=20ba21064884, createdName=sodoo, createdTime=Fri Feb 21 11:38:00 CST 2020, time=2020-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031228, encodeId=96961031228af, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Wed Feb 19 23:38:00 CST 2020, time=2020-02-19, status=1, ipAttribution=)]
    2020-02-19 心介

    房颤,临床上碰到很多哦

    0

相关资讯

心房颤动分级诊疗服务技术方案

心房颤动(以下简称房颤)是一种以快速、无序心房电活动为特征的室上性快速性心律失常。心房因无序电活动而失去有效收缩,导致心脏泵血功能下降,心房内附壁血栓形成,是心力衰竭、缺血性脑卒中等疾病的重要原因。房颤致残率、致死率高,严重影响患者的生活质量,是心血管病患者住院和死亡的常见原因,给家庭和社会带来了沉重负担。对房颤患者早期发现、早期治疗、全程规范管理,可改善患者的生存质量,降低住院率和死亡率。

左心耳干预预防心房颤动患者血栓栓塞事件:目前的认识和建议-2019

自2014年由中华医学会心电生理和起搏分会、中华医学会心血管病分会、中国医师协会心律学专业委员会组织国内相关专家撰写的《左心耳干预预防心房颤动患者血栓栓塞事件:目前的认识和建议》以来的近五年间,国内外有关左心耳(LAA)干预预防心房颤动(简称房颤)患者血栓栓塞事件的基础与临床研究成果不断问世,其研究结果进一步奠定了干预LAA预防房颤患者血栓栓塞事件的理论基础;进一步提升了干预LAA 预防房颤患者血

Circulation:心房颤动持续时间和CHA2DS2-VASc评分影响卒中发病

对心血管植入式电子设备(CIED)患者的研究表明,心房颤动(AF)持续时间与卒中风险存在相关性,尽管与CHA2DS2-VASc评分的相互作用定义不明确。Rachel M.Kaplan等开展的一项研究目的是评估CHA2DS2-VASc评分和AF持续时间对CIED患者卒中和全身性栓塞(SSE)发生率的影响。 研究者将来自Optum©电子健康记录(EHR)去识别化数据库(2007~2017)的

AHA2019丨心房颤动高危人群何以自救:生活方式干预和危险因素控制的重要性

第92届美国心脏协会科学年会(AHA 2019)已于美国费城正式召开。此次年会为期3天,吸引100多个国家众多专家学者参加。来自布列根和女子医院的Christine M Albert教授做客大会主题报告单元,围绕高危人群心房颤动预防中患者的自控因素发表演讲,阐述生活方式干预和危险因素控制的重要意义。布列根和女子医院Christine M Albert教授Andrade J等于2014年发表于Cir

Stroke: 心房颤动及ICH病史人群,使用NOAC可能更安全

在非瓣膜性心房颤动(AF)和颅内出血病史(ICH)的患者中,使用华法林治疗比不治疗有更好的净临床效益。此类患者,尤其是亚裔人群,使用非维生素K拮抗剂口服抗凝剂(NOACs)的数据有限。近期,Stroke杂志发表一项研究,旨在比较NOACs和华法林用于有AF和ICH病史的亚裔人群的有效性和安全性。

Neurology:心房颤动和抗血栓形成药物相互作用对脑出血预后的影响

由此可见,AF和ICH患者的病死率增加。然而,调整抗栓治疗后,AF对死亡率没有单独的影响。相反,抗血栓预处理对无房颤的ICH患者结局具有有害影响,但对有房颤的ICH患者则无效应。

Baidu
map
Baidu
map
Baidu
map