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PLoS One:出生间隔时间越短,婴儿死亡率越高

2015-05-25 MedSci MedSci原创

尽管埃塞俄比亚一直庆祝MDG 4的成就(1990-2015年,埃塞俄比亚地区5岁以下儿童死亡率减少三分之二),但是平均每17名埃塞俄比亚小孩中就会有1名还没有到1岁生日时候夭折。该地区的小孩不到1岁死亡率是非洲地区的最大的平均水平。而在埃塞俄比亚,两胎之间短的出生间隔是否是造成该问题的危险因素,有限和独立的不同研究有不同的结论。因此 Dadi AF对该地区的相关研究进行了荟萃分析,以探究两胎之间的

尽管埃塞俄比亚一直庆祝MDG 4的成就(1990-2015年,埃塞俄比亚地区5岁以下儿童死亡率减少三分之二),但是平均每17名埃塞俄比亚小孩中就会有1名还没有到1岁生日时候夭折。该地区的小孩不到1岁死亡率是非洲地区的最大的平均水平。而在埃塞俄比亚,两胎之间短的出生间隔是否是造成该问题的危险因素,有限和独立的不同研究有不同的结论。因此 Dadi AF对该地区的相关研究进行了荟萃分析,以探究两胎之间的出生间隔时间长短对婴儿死亡率的影响。

研究者通过PUBMED、Google Scholar、PLOS ONE和BMC等数据库检索了独立的关键词以及其组合。使用CMA version 2对纳入研究的合并值进行荟萃分析,通过I2值检验纳入研究间异质性。使用Egger's检验、漏斗图检查纳入研究的发表偏倚。最后使用随机效应模型应用Duval和Tweedie's trim计算纳入研究的合并OR值。

研究者通过检索电子数据库共获得872篇相关文献, 通过筛查后剩余45篇研究有与主题相关的数据,但是最终只有5篇研究符合纳入标准,选入该荟萃分析。纳入分析的所有文章都表明,前面的出生间隔与小于1岁的婴儿死亡率密切相关。最后的将纳入的5篇研究(n=43,909)按随机效应模型(I2=70%)进行荟萃分析也显示,出生时间间隔小于24个月对1岁以下死亡率的合并OR值为2.03 (95% CI: 1.52, 2.70, P<0.05)。

该篇荟萃分析表明,在埃塞俄比亚地区如果两胎间出生间隔时间可以保持到2年以上,那么可以降低目前50%的1岁以下婴儿的死亡率(95% CI: 35%, 63%).。

原始出处:

Dadi AF: A Systematic Review and Meta-Analysis of the Effect of Short Birth Interval on Infant Mortality in Ethiopia. PLoS One 2015, 10(5):e0126759.

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    2015-06-29 owlhealth

    时间近了照顾不过来

    0

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    2015-05-31 huaxipanxing

    看看

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1815998, encodeId=df72181599816, content=<a href='/topic/show?id=9b779e3119a' target=_blank style='color:#2F92EE;'>#间隔时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97311, encryptionId=9b779e3119a, topicName=间隔时间)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKJUlpK5asKgfVAGEUnO6CbNf6icCfycdBO2zX5TWJq27yt434nFicdjf7OsvbOZBOotQdNx6J6PaZQ/132, createdBy=fcba2500108, createdName=ms6519009802973839, createdTime=Fri Aug 14 18:17:00 CST 2015, time=2015-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29816, encodeId=1b0329816af, content=时间近了照顾不过来, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Mon Jun 29 07:26:00 CST 2015, time=2015-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789676, encodeId=4d1e1e89676b2, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sun Sep 27 13:17:00 CST 2015, time=2015-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25671, encodeId=18c6256e1ba, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 31 21:46:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25001, encodeId=269325001df, content=还有我这一说?, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://api.medsci.cn/resource/upload/20150526/IMG5564536F3C41D5237.jpg, createdBy=4c0c1612254, createdName=summer474cn, createdTime=Tue May 26 20:05:00 CST 2015, time=2015-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25002, encodeId=5b91250026c, content=真的学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://api.medsci.cn/resource/upload/20150526/IMG5564536F3C41D5237.jpg, createdBy=4c0c1612254, createdName=summer474cn, createdTime=Tue May 26 20:05:00 CST 2015, time=2015-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24943, encodeId=03e324943dd, content=可以提示婴幼儿保健服务以降低婴儿死亡率, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ec8c108573, createdName=ktorresjie, createdTime=Tue May 26 16:26:00 CST 2015, time=2015-05-26, status=1, ipAttribution=)]
    2015-05-26 summer474cn

    还有我这一说?

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1815998, encodeId=df72181599816, content=<a href='/topic/show?id=9b779e3119a' target=_blank style='color:#2F92EE;'>#间隔时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97311, encryptionId=9b779e3119a, topicName=间隔时间)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKJUlpK5asKgfVAGEUnO6CbNf6icCfycdBO2zX5TWJq27yt434nFicdjf7OsvbOZBOotQdNx6J6PaZQ/132, createdBy=fcba2500108, createdName=ms6519009802973839, createdTime=Fri Aug 14 18:17:00 CST 2015, time=2015-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29816, encodeId=1b0329816af, content=时间近了照顾不过来, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Mon Jun 29 07:26:00 CST 2015, time=2015-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789676, encodeId=4d1e1e89676b2, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sun Sep 27 13:17:00 CST 2015, time=2015-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25671, encodeId=18c6256e1ba, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 31 21:46:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25001, encodeId=269325001df, content=还有我这一说?, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://api.medsci.cn/resource/upload/20150526/IMG5564536F3C41D5237.jpg, createdBy=4c0c1612254, createdName=summer474cn, createdTime=Tue May 26 20:05:00 CST 2015, time=2015-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25002, encodeId=5b91250026c, content=真的学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://api.medsci.cn/resource/upload/20150526/IMG5564536F3C41D5237.jpg, createdBy=4c0c1612254, createdName=summer474cn, createdTime=Tue May 26 20:05:00 CST 2015, time=2015-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24943, encodeId=03e324943dd, content=可以提示婴幼儿保健服务以降低婴儿死亡率, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ec8c108573, createdName=ktorresjie, createdTime=Tue May 26 16:26:00 CST 2015, time=2015-05-26, status=1, ipAttribution=)]
    2015-05-26 summer474cn

    真的学习了

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1815998, encodeId=df72181599816, content=<a href='/topic/show?id=9b779e3119a' target=_blank style='color:#2F92EE;'>#间隔时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97311, encryptionId=9b779e3119a, topicName=间隔时间)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKJUlpK5asKgfVAGEUnO6CbNf6icCfycdBO2zX5TWJq27yt434nFicdjf7OsvbOZBOotQdNx6J6PaZQ/132, createdBy=fcba2500108, createdName=ms6519009802973839, createdTime=Fri Aug 14 18:17:00 CST 2015, time=2015-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29816, encodeId=1b0329816af, content=时间近了照顾不过来, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Mon Jun 29 07:26:00 CST 2015, time=2015-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789676, encodeId=4d1e1e89676b2, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sun Sep 27 13:17:00 CST 2015, time=2015-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25671, encodeId=18c6256e1ba, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 31 21:46:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25001, encodeId=269325001df, content=还有我这一说?, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://api.medsci.cn/resource/upload/20150526/IMG5564536F3C41D5237.jpg, createdBy=4c0c1612254, createdName=summer474cn, createdTime=Tue May 26 20:05:00 CST 2015, time=2015-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25002, encodeId=5b91250026c, content=真的学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://api.medsci.cn/resource/upload/20150526/IMG5564536F3C41D5237.jpg, createdBy=4c0c1612254, createdName=summer474cn, createdTime=Tue May 26 20:05:00 CST 2015, time=2015-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24943, encodeId=03e324943dd, content=可以提示婴幼儿保健服务以降低婴儿死亡率, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ec8c108573, createdName=ktorresjie, createdTime=Tue May 26 16:26:00 CST 2015, time=2015-05-26, status=1, ipAttribution=)]
    2015-05-26 ktorresjie

    可以提示婴幼儿保健服务以降低婴儿死亡率

    0

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