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Dent Mater J：硅酸盐类复合材料对人牙髓细胞增殖和矿化的影响：一项体外评估

2018-09-29 lishiting MedSci原创

硅酸钙牙髓细胞增殖矿化
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这篇研究的目的是为了评估硅酸盐类复合材料对人牙髓细胞(hDPCs)增殖和矿化的影响，并将氢氧化钙(Ca(OH)2, CH)与硅酸三钙(Ca3SiO5, C3S)相比较。

这篇研究的目的是为了评估硅酸盐类复合材料对人牙髓细胞(hDPCs)增殖和矿化的影响，并将氢氧化钙(Ca(OH)2， CH)与硅酸三钙(Ca3SiO5， C3S)相比较。研究对hDPCs分别培养于含CH， C3S和硅酸三钙/硅酸二钙(Ca3SiO5/Ca2SiO4， C3S/C2S)复合材料抽提物的培养基中。CCK-8结果显示，复合材料可以刺激hDPCs的增殖。与纯粹CH和C3S相比，C3S/C2S复合材料可以显著上调成牙本质标志基因和DSPP蛋白的表达。培养于复合材料提取物的HDPCs展现出更强的ALP活性以及茜素红染色。与纯粹的C3S相比，C3S/C2S复合材料更能够增强hDPCs的增殖和成牙本质分化，表明C3S/C2S复合材料具有令人比较满意的生物相容性和生物活性，它可能是一种新型的盖髓剂及牙本质替代材料。原始出处：Wu T， Xu C， et al. Effects of silicate-based composite material on the proliferation and mineralization behaviors of human dental pulp

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    2018-10-28 yahu

    #矿化#

    0

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    2019-06-23 mnda

    #牙髓细胞#

    0

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    2018-10-10 jxrzshh

    #牙髓#

    0

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    2018-11-13 ms4964546379600229

    #复合材料#

    0

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    2018-10-01 chengjn

    #髓细胞#

    0

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    2018-10-01 hb2008ye

    #细胞增殖#

    0

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    2018-09-29 医者仁心5538

    学习了

    0

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