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European Radiology:基于MRI的放射组学分析在乳腺叶状肿瘤与纤维腺瘤鉴别诊断中的价值

2022-03-10 shaosai MedSci原创

乳腺纤维瘤是一种较为罕见的乳腺肿瘤,由上皮和基质成分组成,据报道其发病率不到所有女性乳腺肿瘤的1.0%。

乳腺纤维瘤是一种较为罕见的乳腺肿瘤,由上皮和基质成分组成,据报道其发病率不到所有女性乳腺肿瘤的1.0%。所有的纤维腺瘤都是良性的,而乳腺肿瘤在组织学上可分为良性、交界性或恶性。在治疗纤维腺瘤时,由于复发率高,所有等级的纤维腺瘤都需要进行至少1厘米宽的完全手术切除。

放射线组学分析是一个新兴的转化研究领域,旨在寻找从临床图像中提取的定量信息与其他临床数据之间的关联。肿瘤的异质性是以出血、囊性改变、高细胞密度、坏死和肌样改变等区域为特征的。乳腺MRI的放射组学分析已被应用于区分良性和恶性病变、术前预测前哨淋巴结转移、新辅助化疗的治疗反应、无复发生存以及乳腺癌亚型分析然而很少有研究探讨定量MRI纹理特征对区分乳腺叶状肿瘤和纤维腺瘤的价值。

近日,发表在European Radiology杂志的一项研究开发了一项基于MRI的放射组学机器学习模型,以协助临床术前对乳腺叶状肿瘤及乳腺纤维腺瘤进行准确评估

 

 乳腺叶状肿瘤和纤维腺瘤的磁共振图像。37岁女性病理证实为乳腺叶状肿瘤(a)T2WI、(b)平扫T1WI、(c)DCE-MRI动脉早期、(d)DCE-MRI动脉晚图像25岁女性,病理证实为纤维腺瘤(e) T2WI、(f)平扫T1WI、(g)DCE-MRI动脉早期、(h)DCE-MRI动脉晚图像DCE,动态对比增强;MRI,磁共振成像;T1WI,T1加权成像;T2WI,T2加权成像。

研究表明,基于MRI的放射组学模型可以准确地区分乳腺叶状肿瘤和纤维腺瘤,可以作为临床决策过程中的一个有价值的影像学工具。

 

原文出处

Mitsuteru Tsuchiya,Takayuki Masui,Kazuma Terauchi,et al.MRI-based radiomics analysis for differentiating phyllodes tumors of the breast from fibroadenomas.DOI:10.1007/s00330-021-08510-8.

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    2022-04-09 feather89
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    2022-03-13 ms1000000564332448

    学习了

    0

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    2022-03-10 不能空腹吃早餐

    #学习#学习一下

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1954611, encodeId=6044195461197, content=<a href='/topic/show?id=c12ee727447' target=_blank style='color:#2F92EE;'>#纤维腺瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77274, encryptionId=c12ee727447, topicName=纤维腺瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Tue Jul 26 04:13:16 CST 2022, time=2022-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729415, encodeId=3d1e1e294151c, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Apr 09 14:13:16 CST 2022, time=2022-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1202201, encodeId=4c6e1202201ce, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=106e6543620, createdName=ms1000000564332448, createdTime=Sun Mar 13 12:28:11 CST 2022, time=2022-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506990, encodeId=74011506990fb, content=<a href='/topic/show?id=a66b9624e0c' target=_blank style='color:#2F92EE;'>#鉴别诊断#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96247, encryptionId=a66b9624e0c, topicName=鉴别诊断)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77179846395, createdName=Homburg, createdTime=Fri Mar 11 23:13:16 CST 2022, time=2022-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1201474, encodeId=436512014e4d5, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201225/ad2f9bec445f4a65920cb05c5a0a8452/e4346fc83e4a4efab3aa50b37eacff5e.jpg, createdBy=bef75416446, createdName=不能空腹吃早餐, createdTime=Thu Mar 10 17:53:40 CST 2022, time=2022-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1201432, encodeId=41aa120143250, content=好文章,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJlfgys76DEiaNtbYo2re3ibjrUPTRibEXRyFwAB4aAGiave842S0FQDf0wAoaH226NiaSoPPDzhndsf1g/132, createdBy=88b489038, createdName=yangchou, createdTime=Thu Mar 10 16:18:14 CST 2022, time=2022-03-10, status=1, ipAttribution=)]
    2022-03-10 yangchou

    好文章,谢谢分享。

    0

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