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Stroke：环境粗颗粒物与缺血性卒中住院

2019-03-11 xing.T 网络

环境粗颗粒物缺血性卒中住院
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由此可见，这项全国范围的研究提供了PM10-2.5暴露与增加的缺血性卒中住院率之间短期关联的有力证据，并支持这一假设，即该关联因城市特征而异。

粗颗粒物质（PM10-2.5）对缺血性卒中影响的证据有限且不一致。近日，心血管疾病领域权威杂志Stroke上发表了一篇研究文章，研究人员旨在评估PM10-2.5暴露对中国缺血性卒中住院的急性影响。

研究人员对2014年1月至2016年12月期间中国每日PM10-2.5浓度与每日缺血性卒中住院率之间的关联进行了全国时间序列分析。从城镇职工基本医疗保险数据库中确定了缺血性卒中的住院率。该医疗保险包含了来自1.8亿受益人的数据。研究人员应用城市特定泊松回归来评估PM10-2.5与每日缺血性卒中入院之间的关联，并将城市特定效应估计与随机效应荟萃分析相结合，并进一步评估暴露-效应关系曲线和潜在效应修正。

研究人员在172个中国城市确定了200多万名缺血性卒中住院患者。PM10-2.5浓度每增加10μg/m3（滞后第0天）与缺血性卒中住院率增加0.91％（95％CI为0.73-1.10）相关。调整PM2.5后，该关联仍然显著（百分比变化为0.96％; 95％CI为0.75-1.18）。暴露-效应关系近似为线性，在较低水平（<200μg/m3）具有中等反应，在较高水平具有较陡的反应。在PM10-2.5浓度较低、温度较高或相对湿度较高的城市，这种关联更为密切。

由此可见，这项全国范围的研究提供了PM10-2.5暴露与增加的缺血性卒中住院率之间短期关联的有力证据，并支持这一假设，即该关联因城市特征而异。

原始出处：

Yaohua Tian.et al.Ambient Coarse Particulate Matter and Hospital Admissions for Ischemic Stroke A National Analysis.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.023789

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    2019-04-26 guihongzh

    #缺血性#

    0

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    2019-07-16 12498da4m32(暂无昵称)

    #缺血性卒#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1893160, encodeId=08581893160bd, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Fri Apr 26 11:22:00 CST 2019, time=2019-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806319, encodeId=ce3618063191d, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Jul 16 07:22:00 CST 2019, time=2019-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721785, encodeId=d4941e2178501, content=<a href='/topic/show?id=a15a100e2229' target=_blank style='color:#2F92EE;'>#颗粒物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100722, encryptionId=a15a100e2229, topicName=颗粒物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=106533095611, createdName=lisa449, createdTime=Mon Jun 24 13:22:00 CST 2019, time=2019-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026316, encodeId=0d3f1026316f7, content=卒中虽然是临床上常见病，溶栓，取栓等血管内治疗也很成熟，但是仍然有很多未知问题有待认知！, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Mar 11 16:22:00 CST 2019, time=2019-03-11, status=1, ipAttribution=)]
    2019-06-24 lisa449

    #颗粒物#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1893160, encodeId=08581893160bd, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Fri Apr 26 11:22:00 CST 2019, time=2019-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806319, encodeId=ce3618063191d, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Jul 16 07:22:00 CST 2019, time=2019-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721785, encodeId=d4941e2178501, content=<a href='/topic/show?id=a15a100e2229' target=_blank style='color:#2F92EE;'>#颗粒物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100722, encryptionId=a15a100e2229, topicName=颗粒物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=106533095611, createdName=lisa449, createdTime=Mon Jun 24 13:22:00 CST 2019, time=2019-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026316, encodeId=0d3f1026316f7, content=卒中虽然是临床上常见病，溶栓，取栓等血管内治疗也很成熟，但是仍然有很多未知问题有待认知！, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Mar 11 16:22:00 CST 2019, time=2019-03-11, status=1, ipAttribution=)]
    2019-03-11 健健

    卒中虽然是临床上常见病，溶栓，取栓等血管内治疗也很成熟，但是仍然有很多未知问题有待认知！

    0

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