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Clin Gastroenterology H:多普勒探针在非曲张性上消化道出血中更有效

2019-11-18 不详 MedSci原创

上消化道出血是常见的紧急情况,消化道再出血会增加死亡风险。为了获得最佳结果,需要对高危病变和适当的内镜止血进行正确评估。内窥镜多普勒探针检查(DPE)可以对出血的柱头进行更完整的评估,从而更好地评估内窥镜止血的必要性并确定其完整性。本项研究旨在评估与非内镜上消化道出血患者的高风险柱头的传统内窥镜视觉评估(TEA)相比,使用DPE是否在成本和有效性方面提供额外的优势。

背景与目标
消化道出血是常见的紧急情况,消化道再出血会增加死亡风险。为了获得最佳结果,需要对高危病变和适当的内镜止血进行正确评估。内窥镜多普勒探针检查(DPE)可以对出血的柱头进行更完整的评估,从而更好地评估内窥镜止血的必要性并确定其完整性。本项研究旨在评估与非内镜上消化道出血患者的高风险柱头的传统内窥镜视觉评估(TEA)相比,使用DPE是否在成本和有效性方面提供额外的优势。

方法
研究人员绘制了一个决策树对于主动非静脉曲张上消化道出血进行指数内镜检查的患者,在DPE和TEA方法之间进行选择。从随机对照试验数据中检索临床概率。采集信息的时间范围是指数内窥镜检查后30天。

结果
研究人员发现DPE是优于TEA的策略,因为DPE更有效(92.6%的患者避免再出血,而TEA则为78.6%)且价格更低(8502美元对9104美元)。

结论
在成本效益分析中,研究人员发现DPE是治疗非静脉曲张性上消化道出血高危病变的TEA(传统方法)的更优策略。DPE成本更低且更有效。

原始出处:

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    2020-08-03 许安
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