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J Clin Oncol:坚果的“力量”名不虚传 或可帮结肠癌患者战胜癌症!

2018-03-28 王立群 环球医学

2018年2月发表在《J Clin Oncol》杂志上的一项研究显示,结肠癌患者摄入坚果可以降低复发并改善生存率。坚果成为了战胜癌症的新星?

西方医学之父希波克拉底曾说:“食物是人类治病的最好药品”,可见食物在疗疾祛病方面也有着很重要的作用。坚果,一直是饮食界的“超级食物”,有保护心脏、降低胆固醇等诸多健康获益,备受大家的追捧。

2018年2月发表在《J Clin Oncol》杂志上的一项研究显示,结肠癌患者摄入坚果可以降低复发并改善生存率。坚果成为了战胜癌症的新星?

观察性研究显示,高胰岛素血症患者(包括2型糖尿病、肥胖、久坐生活方式和高糖负荷饮食)结肠癌复发和死亡风险增加。很多研究已经证实,坚果摄入与2型糖尿病代谢综合征和胰岛素抵抗风险降低有关。然而,尚不清楚坚果摄入对结肠癌复发和生存率的影响。

为了考察坚果摄入对患者结肠癌复发和生存率的影响,科学家进行了一项前瞻性观察性研究。

研究人员在826名III期结肠癌患者中开展了该项研究。这些患者通过食物频率调查问卷报告饮食摄入,且纳入了随机辅助化疗研究。

研究人员使用Cox比例风险回归,评估了坚果摄入与癌症复发和死亡率的相关性。

研究发现,在6.5年的中位随访后,与不吃坚果的患者相比,每周食用两份或更多坚果的患者,其无病生存的校正风险比(HR)为0.58,总生存HR为0.43 。

在亚组分析中,仅树坚果摄入有显着获益,无病生存HR为0.54,总生存为0.47。

此外,在其他所有已知或可疑癌症复发和死亡危险因素中,总坚果摄入量与结局改善之间的相关性持续存在。

因此,在III期结肠癌患者中,坚果高消耗饮食可能与癌症复发和死亡率显着降低相关。

相信在证实了坚果对人类健康的这又一大获益之后,人们对坚果的喜爱会更进一步。但要提醒大家的是,再好的东西也要适当食用,否则会过犹不及哦。

原始出处:

Temidayo Fadelu, Sui Zhang, Donna Niedzwiecki,et al. Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). DOI: 10.1200/JCO.2017.75.5413 Journal of Clinical Oncology - published online before print February 28, 2018.

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    2018-12-10 minlingfeng
  2. [GetPortalCommentsPageByObjectIdResponse(id=1865389, encodeId=b270186538928, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Dec 10 16:08:00 CST 2018, time=2018-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300809, encodeId=982a300809b5, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Thu Mar 29 08:07:04 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300698, encodeId=0e3030069861, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu Mar 29 06:14:50 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300628, encodeId=afbb300628bb, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Thu Mar 29 00:04:21 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-03-29 186****0580(小山羊)

    学习了谢谢了

    0

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    2018-03-29 Y—xianghai

    学习了新知识

    0

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    2018-03-29 jihuaijun1112

    学习学习学习

    0

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