Baidu
map

JAMA:口服胰岛素胶囊或可有效控制糖尿病

2015-07-06 佚名 生物谷

近一个世纪以来,胰岛素被认为是挽救糖尿病人的重要疗法,而如今来自国外的研究人员验证了一项棘手的问题,即如果药片包含有给病人注射的相同药物,那么其是否可以用来帮助抑制糖尿病的发生,相关研究成果刊登于国际杂志Journal of the American Medical Association上。文章中研究者确定了这种新型策略是否可以帮助治疗1型糖尿病,一旦证实有效,那么这种疗法或许可以有效普及到1型

近一个世纪以来,胰岛素被认为是挽救糖尿病人的重要疗法,而如今来自国外的研究人员验证了一项棘手的问题,即如果药片包含有给病人注射的相同药物,那么其是否可以用来帮助抑制糖尿病的发生,相关研究成果刊登于国际杂志Journal of the American Medical Association上。

文章中研究者确定了这种新型策略是否可以帮助治疗1型糖尿病,一旦证实有效,那么这种疗法或许可以有效普及到1型糖尿病患者的治疗中。1型糖尿病常常高发于儿童中,研究者对400名儿童和成年人进行研究,调查了这种实验性的胰岛素胶囊是否可以有效抑制或减缓1型糖尿病的发病。

研究结果表明,服用胰岛素胶囊的儿童主要表现出了免疫系统的改变,而这一改变或可帮助有效抑制糖尿病的发生。目前研究者进行的大型研究非常严格,他们随即让参与者服用实验性的胰岛素胶囊或安慰剂,研究者Louis Philipson说道,这种胰岛素胶囊是否可以有效减缓或抑制胰岛素的发生呢?如果其被证实可以,那么这将是糖尿病疗法领域的又一大突破。

大约有125万人患1型糖尿病,而2型糖尿病更为常见,其在美国影响着大约3000万人的健康,而在全世界大约有超过3亿名个体患糖尿病,糖尿病患者机体除了血糖控制较差之外,该病还会对肾脏、心脏以及眼部产生损伤。在1型糖尿病中,胰腺会阻断胰岛素的产生,而当前治疗1型糖尿病的疗法就是通过注射或小型泵来终身替代胰岛素;而对于2型糖尿病而言,机体往往不能够恰当地使用胰岛素,然而患者通过健康的饮食和锻炼就可以减缓疾病的发生或进展。

研究者Wendy Brickman解释道,通过口服胰岛素就可以使其像食物一样被消化,通过哄骗机体损伤的免疫系统使其不攻击产胰岛素的细胞;胰岛素胶囊/药片目前已经被研究作为糖尿病的疗法了,但研究者所面临的挑战是寻找一种策略来使得药物在进入血液后在消化的过程中不被降解;目前研究者希望通过后期的研究来有效改善这种新型胰岛素胶囊的运输,进而使其可以更好地帮助糖尿病患者控制血糖。

原始出处:

Lindsey Tanner.Could insulin pills prevent diabetes? Big study seeks answer.MedicalXpress.July 3, 2015.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=265617, encodeId=bb1e26561e28, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Thu Nov 30 09:55:12 CST 2017, time=2017-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749560, encodeId=d3441e4956085, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Mon Feb 29 23:24:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085555, encodeId=01e4208555579, content=<a href='/topic/show?id=ada383915fb' target=_blank style='color:#2F92EE;'>#胰岛素胶囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83915, encryptionId=ada383915fb, topicName=胰岛素胶囊)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Nov 20 01:24:00 CST 2015, time=2015-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32533, encodeId=03653253335, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Mon Jul 13 00:01:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31639, encodeId=57e431639d0, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:30:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420614, encodeId=3718142061487, content=<a href='/topic/show?id=787b38232d6' target=_blank style='color:#2F92EE;'>#口服胰岛素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38232, encryptionId=787b38232d6, topicName=口服胰岛素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f19a3601771, createdName=by2010, createdTime=Wed Jul 08 04:24:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
    2017-11-30 1e145228m78(暂无匿称)

    学习了谢谢作者分享!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=265617, encodeId=bb1e26561e28, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Thu Nov 30 09:55:12 CST 2017, time=2017-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749560, encodeId=d3441e4956085, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Mon Feb 29 23:24:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085555, encodeId=01e4208555579, content=<a href='/topic/show?id=ada383915fb' target=_blank style='color:#2F92EE;'>#胰岛素胶囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83915, encryptionId=ada383915fb, topicName=胰岛素胶囊)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Nov 20 01:24:00 CST 2015, time=2015-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32533, encodeId=03653253335, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Mon Jul 13 00:01:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31639, encodeId=57e431639d0, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:30:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420614, encodeId=3718142061487, content=<a href='/topic/show?id=787b38232d6' target=_blank style='color:#2F92EE;'>#口服胰岛素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38232, encryptionId=787b38232d6, topicName=口服胰岛素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f19a3601771, createdName=by2010, createdTime=Wed Jul 08 04:24:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
    2016-02-29 baoya
  3. [GetPortalCommentsPageByObjectIdResponse(id=265617, encodeId=bb1e26561e28, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Thu Nov 30 09:55:12 CST 2017, time=2017-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749560, encodeId=d3441e4956085, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Mon Feb 29 23:24:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085555, encodeId=01e4208555579, content=<a href='/topic/show?id=ada383915fb' target=_blank style='color:#2F92EE;'>#胰岛素胶囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83915, encryptionId=ada383915fb, topicName=胰岛素胶囊)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Nov 20 01:24:00 CST 2015, time=2015-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32533, encodeId=03653253335, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Mon Jul 13 00:01:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31639, encodeId=57e431639d0, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:30:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420614, encodeId=3718142061487, content=<a href='/topic/show?id=787b38232d6' target=_blank style='color:#2F92EE;'>#口服胰岛素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38232, encryptionId=787b38232d6, topicName=口服胰岛素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f19a3601771, createdName=by2010, createdTime=Wed Jul 08 04:24:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=265617, encodeId=bb1e26561e28, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Thu Nov 30 09:55:12 CST 2017, time=2017-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749560, encodeId=d3441e4956085, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Mon Feb 29 23:24:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085555, encodeId=01e4208555579, content=<a href='/topic/show?id=ada383915fb' target=_blank style='color:#2F92EE;'>#胰岛素胶囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83915, encryptionId=ada383915fb, topicName=胰岛素胶囊)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Nov 20 01:24:00 CST 2015, time=2015-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32533, encodeId=03653253335, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Mon Jul 13 00:01:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31639, encodeId=57e431639d0, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:30:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420614, encodeId=3718142061487, content=<a href='/topic/show?id=787b38232d6' target=_blank style='color:#2F92EE;'>#口服胰岛素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38232, encryptionId=787b38232d6, topicName=口服胰岛素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f19a3601771, createdName=by2010, createdTime=Wed Jul 08 04:24:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
    2015-07-13 保守主义

    有意思

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=265617, encodeId=bb1e26561e28, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Thu Nov 30 09:55:12 CST 2017, time=2017-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749560, encodeId=d3441e4956085, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Mon Feb 29 23:24:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085555, encodeId=01e4208555579, content=<a href='/topic/show?id=ada383915fb' target=_blank style='color:#2F92EE;'>#胰岛素胶囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83915, encryptionId=ada383915fb, topicName=胰岛素胶囊)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Nov 20 01:24:00 CST 2015, time=2015-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32533, encodeId=03653253335, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Mon Jul 13 00:01:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31639, encodeId=57e431639d0, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:30:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420614, encodeId=3718142061487, content=<a href='/topic/show?id=787b38232d6' target=_blank style='color:#2F92EE;'>#口服胰岛素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38232, encryptionId=787b38232d6, topicName=口服胰岛素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f19a3601771, createdName=by2010, createdTime=Wed Jul 08 04:24:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
    2015-07-08 huaxipanxing

    看看

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=265617, encodeId=bb1e26561e28, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Thu Nov 30 09:55:12 CST 2017, time=2017-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749560, encodeId=d3441e4956085, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Mon Feb 29 23:24:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085555, encodeId=01e4208555579, content=<a href='/topic/show?id=ada383915fb' target=_blank style='color:#2F92EE;'>#胰岛素胶囊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83915, encryptionId=ada383915fb, topicName=胰岛素胶囊)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Nov 20 01:24:00 CST 2015, time=2015-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32533, encodeId=03653253335, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Mon Jul 13 00:01:00 CST 2015, time=2015-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31639, encodeId=57e431639d0, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:30:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420614, encodeId=3718142061487, content=<a href='/topic/show?id=787b38232d6' target=_blank style='color:#2F92EE;'>#口服胰岛素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38232, encryptionId=787b38232d6, topicName=口服胰岛素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f19a3601771, createdName=by2010, createdTime=Wed Jul 08 04:24:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
Baidu
map
Baidu
map
Baidu
map