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Sci Rep:寒冷的天气能够增加哮喘和过敏性鼻炎患者呼吸道症状和功能性障碍

2018-07-13 AlexYang MedSci原创

寒冷的天气能够影响呼吸上皮并且能够诱导支气管高反应性。最近,有研究人员假设患有过敏性鼻炎或者/和哮喘的患者个体要比那些没有上述疾病的个体经历更多的寒冷天气相关的功能性障碍(FD)和健康问题(EH)。研究人员进行了一个基于群体的研究,包括了7330名年龄在25-74岁之间的成年人;并利用了一个调查问卷测量了感兴趣的决定因素,这些因素包括了医生诊断的哮喘和过敏性鼻炎、治疗结果以及寒冷天气相关的FD和E

寒冷的天气能够影响呼吸上皮并且能够诱导支气管高反应性。最近,有研究人员假设患有过敏性鼻炎或者/和哮喘的患者个体要比那些没有上述疾病的个体经历更多的寒冷天气相关的功能性障碍(FD)和健康问题(EH)。

研究人员进行了一个基于群体的研究,包括了7330名年龄在25-74岁之间的成年人;并利用了一个调查问卷测量了感兴趣的决定因素,这些因素包括了医生诊断的哮喘和过敏性鼻炎、治疗结果以及寒冷天气相关的FD和EH。研究发现,寒冷天气相关的FD和EH流行度分别为20.3%和10.3%。在泊松回归中,FD的风险在过敏性鼻炎(调整后流行率(PR)1.19;男性:95% CI 1.04-1.37; 1.26,;女性:95% CI 1.08-1.46)、哮喘(分别为1.29, 0.93-1.80; 1.36, 0.92-2.02)以及两种疾病的组合(分别为1.16, 0.90-1.50; 1.40, 1.12-1.76)中均增加。同样,寒冷天气相关的EH也与过敏性鼻炎(男性:1.53, 1.15,-2.04; 女性:1.78, 1.43-2.21)、哮喘(4.28, 2.88-6.36; 3.77, 2.67-5.34)和它们的组合(4.02, 2.89-5.59; 4.60, 3.69-5.73)相关。

最后,研究人员指出,患有过敏性鼻炎或者/和哮喘的患者对寒冷天气相关的FD和EH要比没有上述呼吸道疾病的个体更加易感。

原始出处:


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    2018-08-04 xugc
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    2018-07-15 zhmscau
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    2018-07-15 huagfeg

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