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BMC Cancer:临床早期胃癌术前术后淋巴结转移预测差异

2015-12-16 Seven L 译 MedSci原创

病理分期的早期胃癌其病理学因素和淋巴结转移之间的关系已经进行了广泛研究,但是早期胃癌临床分期的早期胃癌其术前因素和淋巴结转移的关系并没有进行过研究。因此研究者进行了一项研究,调查术前术后差异。研究纳入了2011年1月到2013年12月间的1042名临床分期早期胃癌患者,进行胃切除术与淋巴切除术。收集术前术后相关数据进行亚组分析,使用独立预测因素计算ROC曲线。术前术后主要差异有溃疡的存在、大体分型

按病理分期的早期胃癌其病理学因素和淋巴结转移之间的关系,过去已经进行了许多广泛研究,但是几乎没有对早期胃癌的早期胃癌切除术前因素和淋巴结转移的关系的研究。因此研究者进行了一项研究,调查术前术后差异。

研究纳入了2011年1月到2013年12月间的1042名临床分期早期胃癌患者,进行胃切除术与淋巴切除术。收集术前术后相关数据进行亚组分析,使用独立预测因素计算ROC曲线。

术前术后主要差异有溃疡的存在、大体分型、组织学。多因素分析识别了以下几个与淋巴结转移相关独立预测因素:术后包括年龄 (p=0.002)、肿瘤大小(p < 0.001)、浸润深度(p < 0.001);术前有年龄(p = 0.017)、存在溃疡(p = 0.037)、肿瘤大小(p = 0.009)、CT上淋巴结转移(p = 0.002)。术后因素对预测淋巴结转移ROC为0.824,术前为0.660。


研究结果表明临床分期的早期胃癌其术前预测淋巴结是否转移的因素存在不足,而外科医生应该意识到这一点。

原始出处:


Nakagawa M,Choi YY, An JY,et al.Difficulty of predicting the presence of lymph node metastases in patients with clinical early stage gastric cancer: a case control study.BMC Cancer. 2015 Dec 1.

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    2016-01-13 Lynee劲飞扬

    学业

    0

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    2015-12-28 wzf990214

    赞一个

    0

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    2015-12-28 wzf990214

    不错的

    0

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    2015-12-28 wzf990214

    有意思

    0

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    2015-12-26 hixiaoluo

    好文章,值得看。

    0

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    2015-12-18 sodoo
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