Baidu
map

Diabetes Care:高温烹饪食物或可增加胰岛素抵抗

2014-01-21 完美事业 丁香园

研究要点: 1、高AGEs饮食增加胰岛素抵抗的发生;2、调整烹饪方法可减少AGEs含量,从而降低IR发生风险;3、摄入果糖对AGEs含量没有影响。 高温烹饪食物可导致晚期糖基化终产物(AGEs)的形成, AGEs被认为可引起2型糖尿病患者葡萄糖代谢受损。此外,大量摄取果糖可能会影响内源性AGEs的形成。【原文下载】 为了研究果糖的摄取或烹饪方式影响食物的AGE含量后,是否会影

研究要点:

1、高AGEs饮食增加胰岛素抵抗的发生;

2、调整烹饪方法可减少AGEs含量,从而降低IR发生风险;

3、摄入果糖对AGEs含量没有影响。

高温烹饪食物可导致晚期糖基化终产物(AGEs)的形成, AGEs被认为可引起2型糖尿病患者葡萄糖代谢受损。此外,大量摄取果糖可能会影响内源性AGEs的形成。【原文下载】

为了研究果糖的摄取或烹饪方式影响食物的AGE含量后,是否会影响超重个体的胰岛素敏感性,来自丹麦哥本哈根大学的Mark博士等进行了一项研究,发现高AGE饮食可能会增加胰岛素抵抗的发生,调整烹饪方法可减少AGEs含量,而摄入果糖对AGEs含量没有影响。研究结果在线发表于2013年8月19日的《糖尿病治疗》(Diabetes Care)杂志上。

74名超重妇女随机分为2组,分别接受高AGE和低AGE饮食,同时补充摄入果糖或葡萄糖饮料,为期4周。干预研究前后,分别测定受试者空腹和口服葡萄糖耐量试验2h后的血糖和胰岛素浓度。计算稳态模型评估胰岛素抵抗指数(HOMA-IR)和胰岛素敏感性指数。采用液相色谱串联质谱法测定食物和尿液中AGE浓度,以评估AGE吸收和排泄情况。

研究期间,经人体测量指标校正后,与高AGE饮食组比较,低AGE饮食降低尿液AGEs,空腹胰岛素浓度和HOMA-IR。补充果糖对结果没有任何影响。

研究发现,高AGE饮食可能会增加胰岛素抵抗的发生,调整烹饪方法可减少AGEs含量,而适度摄入果糖对AGEs含量没有影响。

研究背景:

摄入过多高度加工处理后的食物 ,导致机体晚期糖化终产物(AGEs)的暴露量增加。AGEs由Maillard反应生成,这一反应对食物的色、香、味形成具有重要作用。烹饪的温度是一个关键的因素,高温烹饪如烘烤、焙烧、油煎和烧烤是晚期糖化的强效启动子。

因此,在多种食物中可发现高水平的AGEs,如面包、熟肉制品和焙炒咖啡。研究显示,食物中提取的AGEs能够诱导体外氧化应激和炎症反应,因此认为,食物中AGEs是体内促氧化剂。

来自动物研究的大量证据表明,高温烹饪食物AGEs含量较高,从而导致胰岛素水平、胰岛素抵抗(IR)和2型糖尿病发病增加。此外,一项最新的研究发现,丙酮醛衍生物诱发IR、损伤胰岛素信号、诱发小鼠前炎症表型表达,这些证据进一步表明食物中AGEs在2型糖尿病发病机制中的作用。

已有研究报道血浆中AGEs与IR标志物具有一定的相关性。AGEs限制性饮食对2型糖尿病患者葡萄糖代谢的有益作用已经得到证明,但是接受相同饮食的对照者的IR标志物并没有得到改善。在另一项研究中,与低温处理食物组比较,高温处理食物组稳态模型评估胰岛素抵抗指数(HOMA-IR)增加,但是HOMA-IR的改变并未经人体测量指标或饮食差异校正。

内源性形成的AGEs是羰基应激增加所导致的结果,尤其是在糖尿病中。果糖是多个AGE前体形成的重要反应物,但是其对内源性AGE形成的可能影响尚未研究。因此,研究人员推测,大量摄入果糖可能会加剧内源性AGE形成,因为肝脏果糖摄取不像葡萄糖摄取一样受严格的调控,其可通过三碳糖的酵解途径增加AGE形成。

原文出处:
Mark AB, Poulsen MW, Andersen S, Andersen JM, Bak MJ, Ritz C, Holst JJ, Nielsen J, de Courten B, Dragsted LO, Bügel SG.Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women.Diabetes Care. 2014 Jan;37(1):88-95. doi: 10.2337/dc13-0842. Epub 2013 Aug 19.【原文下载】

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1636798, encodeId=30aa1636e9840, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 18 06:09:00 CST 2014, time=2014-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749460, encodeId=981b1e4946098, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Aug 27 05:09:00 CST 2014, time=2014-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647157, encodeId=b846164e1577c, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Feb 03 01:09:00 CST 2014, time=2014-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759391, encodeId=40f91e5939157, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jan 24 08:09:00 CST 2014, time=2014-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901171, encodeId=5a1819011e173, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Dec 17 08:09:00 CST 2014, time=2014-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416648, encodeId=c22f14166482c, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506511, encodeId=cddc150651117, content=<a href='/topic/show?id=89061024e70b' target=_blank style='color:#2F92EE;'>#高温#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102477, encryptionId=89061024e70b, topicName=高温)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90ad9763425, createdName=lqrandywkz, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1636798, encodeId=30aa1636e9840, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 18 06:09:00 CST 2014, time=2014-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749460, encodeId=981b1e4946098, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Aug 27 05:09:00 CST 2014, time=2014-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647157, encodeId=b846164e1577c, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Feb 03 01:09:00 CST 2014, time=2014-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759391, encodeId=40f91e5939157, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jan 24 08:09:00 CST 2014, time=2014-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901171, encodeId=5a1819011e173, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Dec 17 08:09:00 CST 2014, time=2014-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416648, encodeId=c22f14166482c, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506511, encodeId=cddc150651117, content=<a href='/topic/show?id=89061024e70b' target=_blank style='color:#2F92EE;'>#高温#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102477, encryptionId=89061024e70b, topicName=高温)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90ad9763425, createdName=lqrandywkz, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=)]
    2014-08-27 baoya
  3. [GetPortalCommentsPageByObjectIdResponse(id=1636798, encodeId=30aa1636e9840, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 18 06:09:00 CST 2014, time=2014-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749460, encodeId=981b1e4946098, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Aug 27 05:09:00 CST 2014, time=2014-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647157, encodeId=b846164e1577c, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Feb 03 01:09:00 CST 2014, time=2014-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759391, encodeId=40f91e5939157, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jan 24 08:09:00 CST 2014, time=2014-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901171, encodeId=5a1819011e173, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Dec 17 08:09:00 CST 2014, time=2014-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416648, encodeId=c22f14166482c, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506511, encodeId=cddc150651117, content=<a href='/topic/show?id=89061024e70b' target=_blank style='color:#2F92EE;'>#高温#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102477, encryptionId=89061024e70b, topicName=高温)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90ad9763425, createdName=lqrandywkz, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1636798, encodeId=30aa1636e9840, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 18 06:09:00 CST 2014, time=2014-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749460, encodeId=981b1e4946098, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Aug 27 05:09:00 CST 2014, time=2014-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647157, encodeId=b846164e1577c, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Feb 03 01:09:00 CST 2014, time=2014-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759391, encodeId=40f91e5939157, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jan 24 08:09:00 CST 2014, time=2014-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901171, encodeId=5a1819011e173, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Dec 17 08:09:00 CST 2014, time=2014-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416648, encodeId=c22f14166482c, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506511, encodeId=cddc150651117, content=<a href='/topic/show?id=89061024e70b' target=_blank style='color:#2F92EE;'>#高温#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102477, encryptionId=89061024e70b, topicName=高温)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90ad9763425, createdName=lqrandywkz, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1636798, encodeId=30aa1636e9840, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 18 06:09:00 CST 2014, time=2014-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749460, encodeId=981b1e4946098, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Aug 27 05:09:00 CST 2014, time=2014-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647157, encodeId=b846164e1577c, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Feb 03 01:09:00 CST 2014, time=2014-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759391, encodeId=40f91e5939157, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jan 24 08:09:00 CST 2014, time=2014-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901171, encodeId=5a1819011e173, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Dec 17 08:09:00 CST 2014, time=2014-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416648, encodeId=c22f14166482c, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506511, encodeId=cddc150651117, content=<a href='/topic/show?id=89061024e70b' target=_blank style='color:#2F92EE;'>#高温#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102477, encryptionId=89061024e70b, topicName=高温)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90ad9763425, createdName=lqrandywkz, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1636798, encodeId=30aa1636e9840, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 18 06:09:00 CST 2014, time=2014-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749460, encodeId=981b1e4946098, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Aug 27 05:09:00 CST 2014, time=2014-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647157, encodeId=b846164e1577c, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Feb 03 01:09:00 CST 2014, time=2014-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759391, encodeId=40f91e5939157, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jan 24 08:09:00 CST 2014, time=2014-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901171, encodeId=5a1819011e173, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Dec 17 08:09:00 CST 2014, time=2014-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416648, encodeId=c22f14166482c, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506511, encodeId=cddc150651117, content=<a href='/topic/show?id=89061024e70b' target=_blank style='color:#2F92EE;'>#高温#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102477, encryptionId=89061024e70b, topicName=高温)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90ad9763425, createdName=lqrandywkz, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=)]
    2014-01-23 yhy100201
  7. [GetPortalCommentsPageByObjectIdResponse(id=1636798, encodeId=30aa1636e9840, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Jul 18 06:09:00 CST 2014, time=2014-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1749460, encodeId=981b1e4946098, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Aug 27 05:09:00 CST 2014, time=2014-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647157, encodeId=b846164e1577c, content=<a href='/topic/show?id=02286e2683e' target=_blank style='color:#2F92EE;'>#烹饪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67268, encryptionId=02286e2683e, topicName=烹饪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b9e923392426, createdName=gao_jian4225, createdTime=Mon Feb 03 01:09:00 CST 2014, time=2014-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759391, encodeId=40f91e5939157, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jan 24 08:09:00 CST 2014, time=2014-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901171, encodeId=5a1819011e173, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Dec 17 08:09:00 CST 2014, time=2014-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416648, encodeId=c22f14166482c, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506511, encodeId=cddc150651117, content=<a href='/topic/show?id=89061024e70b' target=_blank style='color:#2F92EE;'>#高温#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102477, encryptionId=89061024e70b, topicName=高温)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90ad9763425, createdName=lqrandywkz, createdTime=Thu Jan 23 06:09:00 CST 2014, time=2014-01-23, status=1, ipAttribution=)]
    2014-01-23 lqrandywkz
Baidu
map
Baidu
map
Baidu
map