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JAMA Intern Med:台湾学者发现慢阻肺患者起始应用支气管扩张剂30天内心血管病风险增加,

2018-01-04 许菁 中国循环杂志

我国台湾学者发现,COPD患者在起始应用长效β2受体阻滞剂或者长效毒蕈碱拮抗剂的30天内,其心血管病包括冠心病、心律失常、心力衰竭或缺血性中风的风险大约增加50%。

我国台湾学者发现,COPD患者在起始应用长效β2受体阻滞剂或者长效毒蕈碱拮抗剂的30天内,其心血管病包括冠心病、心律失常、心力衰竭或缺血性中风的风险大约增加50%。


研究者提醒,COPD在启动长效β2受体阻滞剂或者长效毒蕈碱拮抗剂治疗的30天,临床医生应警惕患者的心血管系统的症状。

数据显示,长效β2受体阻滞剂、长效毒蕈碱拮抗剂分别使心血管病风险增加50%和52%。两者联合应用,则心血管病风险增加1倍多。

长效支气管扩张剂导致的心血管病风险不受患者基线心血管病状态的影响。

在用药30天后,使用长效支气管扩张剂的心血管病风险逐渐减弱。

研究纳入了40岁及以上,1年内进行了两次门诊或一次住院治疗的28万例COPD患者。2年内有37719名被诊断为严重心血管病.
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    2018-11-14 lsj637
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    2018-02-22 smlt2008
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    2018-01-05 owlhealth

    学习了.不错

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