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Hypertension:家用与动态血压监测确定的夜间高血压在预测心血管事件的比较

2020-06-16 MedSci原创 MedSci原创

这是第一项比较性前瞻性研究,表明HBPM(独立于诊室SBP)定义的无法控制的夜间高血压是未来心血管事件的预测指标。

据报道,家用型血压监测(HBPM)方法在夜间测量血压和检测夜间高血压方面可与动态血压监测(ABPM)媲美。近日,血管权威杂志Hypertension上发表了一篇研究文章,该研究旨在直接比较HBPM和ABPM在检测夜间高血压方面的能力,以预测未来的心血管事件

研究人员分析了J-HOP(日本血压晨峰)试验中1005名参与者的夜间血压(通过HBPM和ABPM测量)数据。在7.6±3.4年的随访期内,共发生了80次心血管疾病事件。研究人群中的大多数(91.8%)为高血压患者,而80.7%的参与者服用降压药。

夜间家用血压监测获得的收缩压(SBP)高于夜间动态SBP(123.0±14.6 vs. 120.3±14.4 mmHg,P<0.001)。夜间高血压定义为夜间家用或动态SBP≥120mmHg。HBPM和ABPM定义的夜间高血压参与者人数分别为564(56.1%)和469(46.7%)。HBPM定义的夜间高血压与未来发生心血管事件的风险增加相关:总心血管事件(冠状动脉疾病和卒中事件;1.78 [1.00–3.15])和卒中(2.65 [1.14–6.20]),与诊室SBP无关。ABPM定义的夜间高血压没有这方面的结果。

这是第一项比较性前瞻性研究,表明HBPM(独立于诊室SBP)定义的无法控制的夜间高血压是未来心血管事件的预测指标。

原始出处:

Gontse Gratitude Mokwatsi.et al.Direct Comparison of Home Versus Ambulatory Defined Nocturnal Hypertension for Predicting Cardiovascular Events The Japan Morning Surge-Home Blood Pressure (J-HOP) Study.Hypertension.2020.https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.119.14344

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