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OGT拓展肺癌Cytocell FISH探针组合

2016-09-14 佚名 Oxford Gene Technolo

分子遗传学公司Oxford Gene Technology(牛津基因技术公司,简称OGT)已推出两款获得CE-IVD认证标志的新型荧光原位杂交(FISH)探针,进一步扩大了其广泛的肺癌探针产品组合。

英国牛津2016年9月13日电 /美通社/ --

新款探针推进了非小细胞肺癌的诊断和分层治疗

分子遗传学公司Oxford Gene Technology(牛津基因技术公司,简称OGT)已推出两款获得CE-IVD认证标志的新型荧光原位杂交(FISH)探针,进一步扩大了其广泛的肺癌探针产品组合。Cytocell Aquarius® ROS1Plus Breakapart和RET Breakapart探针*能够准确检测到与最常见的肺癌——非小细胞肺癌相关的基因组重组。这两款新产品进一步完善了OGT现有的非小细胞肺癌探针系列(包括ALK Breakapart、EGFR Amplification和EML Breakapart),为诊断和患者分层提供了完整的解决方案。


肺癌是发病率最高的肿瘤,也是男性癌症死因之首。2012年,全球新增180万肺癌病例[1],其中85%为非小细胞肺癌[2]。皇家马斯登NHS信托基金会(Royal Marsden NHS Foundation Trust)的临床科学家Manisha Maurya就新型Cytocell探针的重要性表示:“非小细胞肺癌可分成不同的分子分型,针对正确分型进行准确基因组识别对靶向治疗来说最为重要。在我们的有效性研究中,针对非小细胞肺癌的新型Cytocell探针提供了高密度清晰信号,便于实现检测结果的可视化和记录。这些探针将进一步增强我们的非小细胞肺癌分层和治疗能力。”

OGT病理学高级产品经理Steve Chatters称:“癌症研究正在快速推进。OGT与领先的临床科学人员合作,利用最新科学认识开发创新产品。我们的新型Cytocell Aquarius ROS1 Plus Breakapart探针就是例证,该探针不仅能够覆盖ROS1区域,还能覆盖ROS1-GOPC融合中删除的区域,从而提供更加完整的分析。”

这些探针提供两种经济尺寸,已预装在杂交缓冲器中,有利于节省时间并将错误率降到最低。Cytocell FISH探针经过完全优化可用于石蜡包埋的甲醛固定样本,提供高密度信号,同时将背景噪声降到最低,从而实现准确、可靠的检测结果和令人确信的诊断。

登录http://www.ogt.com/NSCLC下载OGT的最新宣传册,了解有关针对非小细胞肺癌的Cytocell FISH系列探针的详情。

参考

  1. Ervik M等人撰写的《Cancer Today》(2016年)。法国里昂国际癌症研究机构。《Cancer Today》,相关网址:http://gco.iarc.fr/today,2016年8月30日访问
  2. Molina JR等人撰写的《非小细胞肺癌:传染病、风险因素、治疗和存活》(2008年)。收录在梅奥医学中心(Mayo Clinic)论文集中。梅奥医学中心。83(5):584-594

编者注:

Oxford Gene Technology简介

Oxford Gene Technology为领先的临床和学术研究机构提供世界级遗传学研究解决方案。OGT由Edwin Southern教授创立,其客户遍及全球60多个国家,公司已在不断增长的庞大基因组药物市场上建立了强大的影响力,并且市场份额也在不断扩大。OGT的Cytocell®、CytoSure™和SureSeq™系列荧光原位杂交探针、微阵列和新一代测序产品提供高品质基因分析,实现致病性基因突变型遗传病的准确识别和确认。

* Cytocell Aquarius® RET Breakapart和 ROS1 Plus Breakapart探针已获得CE-IVD认证标志,于2016年9月8日推出。

CytoSure™、SureSeq™和myProbes®仅供研究使用,不用于诊断。有些Cytocell产品可能不在美国推出。

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    2016-11-25 维他命
  3. 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likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 15:33:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127652, encodeId=bc2712e65257, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 14:51:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127599, encodeId=099312e5996f, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 14:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127306, encodeId=92b912e306f8, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127307, encodeId=d20912e30710, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2017-05-07 仁医06
  4. 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createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127307, encodeId=d20912e30710, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  5. 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createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127307, encodeId=d20912e30710, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  6. 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createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127307, encodeId=d20912e30710, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  7. 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createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127307, encodeId=d20912e30710, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Sep 15 09:44:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  8. 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    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  9. 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    2016-09-15 doctorJiangchao

    继续学习

    0

  10. 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    2016-09-15 doctorJiangchao

    继续关注

    0

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