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用心肺运动试验评估心衰患者的整体功能状态和预后有技巧

2019-05-31 xujing 中国循环杂志

目前,心肺运动试验(CPET)是评估可活动慢性心衰(CHF )患者的整体功能状态和预后的唯一公认的量化指标。

目前,心肺运动试验(CPET)是评估可活动慢性心衰(CHF )患者的整体功能状态和预后的唯一公认的量化指标。

CPET 的核心参数峰值摄氧量(PVO2)及峰值摄氧量预计值百分比(% pPVO2)等指标预测 CHF 患者预后的作用优于纽约心脏协会(NYHA)心功能分级、左心室射血分数(LVEF)等传统评估方法。

既往 PVO2 评估 CHF 患者预后的界值是 β 受体阻滞剂的广泛应用之前经临床验证的。

黄洁等发表文章指出,当今,现代药物和器械治疗等新近治疗方法明显提高 CHF 患者的生存率,也对PVO2预测CHF预后界值产生了不同的影响。

多项临床数据表明,不能耐受 β 受体阻滞剂的 CHF 患者预测不良预后的界值 PVO2 =14 ml/(kg·min)不变。

而对于服用 β 受体阻滞剂的 CHF 患者,PVO2 预测其不良预后的界值变为 12 ml/(kg·min)。

心脏再同步治疗(CRT)对 PVO2 评估 CHF 患者预后的界值无影响。

根据 12 ml/(kg·min)

对于青少年 CHF 患者,峰值摄氧量预计值百分比(% pPVO2)可作为补充评估措施。

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