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Pak J Med Sci:阿奇霉素和红霉素治疗小儿支原体肺炎的比较

2020-02-19 不详 网络

本研究旨在探究和对比阿奇霉素和红霉素对小儿支原体肺炎的临床疗效。纳入2017年11月至2018年9月期间入院的132例支原体肺炎患儿作为研究对象。根据随机数字表将所有儿童分为观察组和对照组,每组66个。观察组给予阿奇霉素治疗,对照组给予红霉素治疗。比较两组的治疗效果,不良反应发生率和临床症状消失时间。结果显示,观察组总有效率98.04%,对照组总有效率74.51%,有显著差异(X2 = 7.184

本研究旨在探究和对比阿奇霉素和红霉素对小儿支原体肺炎的临床疗效。

纳入2017年11月至2018年9月期间入院的132例支原体肺炎患儿作为研究对象。根据随机数字表将所有儿童分为观察组和对照组,每组66个。观察组给予阿奇霉素治疗,对照组给予红霉素治疗。比较两组的治疗效果,不良反应发生率和临床症状消失时间。

结果显示,观察组总有效率98.04%,对照组总有效率74.51%,有显著差异(X2 = 7.184,P = 0.007)。观察组不良反应发生率为15.69%,明显低于对照组(41.18%)(X2 = 6.376,P = 0.002)。观察组发热,咳嗽,罗音,X线影消失消失明显早于对照组,差异有统计学意义(P <0.05)。

综上所述,该研究结果表明,与红霉素相比,阿奇霉素在儿童支原体肺炎的治疗中更有效。阿奇霉素可进一步缩短临床症状和体征的改善时间,不良反应少,安全性高,值得临床应用。

原始出处:

Han R, Yu Q, et al., Comparison of azithromycin and erythromycin in the treatment of mycoplasma pneumonia in children. Pak J Med Sci. 2020 Jan-Feb;36(2):156-159. doi: 10.12669/pjms.36.2.1441.

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