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2015辅助生殖促排卵药物治疗专家共识发布

2016-07-20 MedSci MedSci原创

辅助生殖技术(assisted reproductive technology,ART)的重要内容之一是诱导排卵(ovulation induction,OI)和控制性卵巢刺激(controlled ovarian stimulation,COS),OI指对排卵障碍患者应用药物或手术方法诱发排卵,一般以诱导单卵泡或少数卵泡发育为目的。COS指以药物手段在可控范围内诱发多卵泡发育和成熟,其应用对象多

辅助生殖技术(assisted reproductive technology,ART)的重要内容之一是诱导排卵(ovulation induction,OI)和控制性卵巢刺激(controlled ovarian stimulation,COS),OI指对排卵障碍患者应用药物或手术方法诱发排卵,一般以诱导单卵泡或少数卵泡发育为目的。COS指以药物手段在可控范围内诱发多卵泡发育和成熟,其应用对象多有正常排卵功能。


辅助生殖技术(ART)的重要内容之一是促排卵治疗,其应用改善了临床妊娠率,但多胎妊娠、卵巢过度刺激综合征(OHSS)等并发症发生几率较高。

促排卵最常用药物为克罗米芬(CC)、芳香化酶抑制剂、促性腺激素(Gn)类和促性腺激素释放激素类似物(GnRHa),包括激动剂(GnRH-a)和拮抗剂(GnRH-A)近年来的应用也逐渐增加。各种药物有不同的适应证、禁忌证和用药方案,另外还可使用其他促排卵辅助药物,如口服避孕药(OC)、二甲双胍、多巴胺受体激动剂等,这些促排卵治疗效果可通过常用的疗效评估指标及计算方法来统计。

如何合理、适度地应用促排卵药物,制定标准监测评价指标,越来越成为生殖医生临床实践中需要重点考虑的问题。中华医学会生殖医学分会部分专家结合近年来国内、外相关领域研究进展及临床应用,对促排卵药物在ART中的应用达成共识,指导规范的临床应用,以期为临床生殖医学工作者提供更佳的操作依据。

本指南从以下5个方面介绍:

1、辅助生殖促排卵药物治疗的目标 
2 适应证及禁忌证
3 药物的分类及其药理作用
4 辅助生殖药物治疗方案
5 疗效常用的评估指标及计算方法

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相关会议推荐

2016生殖医学发展前沿论坛——健康发育与生殖研究

会议时间:2016.08.19-2016.08.20 会议地点:上海

会议详情: http://www.bioon.com/z/2016repro-med/


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    2016-07-20 doctorJiangchao

    值得阅读

    0

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    2016-07-20 doctorJiangchao

    继续学习

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    2016-07-20 doctorJiangchao

    继续关注

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