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氟喹诺酮类抗菌药物在儿童应用中的专家共识

2017-12-19 广东省药学会 今日药学.2017.12.

我国临床学者对于18 岁以下的儿童能否使用氟喹诺酮类药物的问题有很大争议,因此本共识介绍氟喹诺酮类药物在儿童的药代动力学特点及安全性问题(主要集中在软骨、关节的不良反应),以及目前儿童使用喹诺酮类药物的一些情况,以期给临床指导。

中文标题:

氟喹诺酮类抗菌药物在儿童应用中的专家共识

发布机构:

广东省药学会

发布日期:

2017-12-19

简要介绍:

我国临床学者对于18 岁以下的儿童能否使用氟喹诺酮类药物的问题有很大争议,因此本共识介绍氟喹诺酮类药物在儿童的药代动力学特点及安全性问题(主要集中在软骨、关节的不良反应),以及目前儿童使用喹诺酮类药物的一些情况,以期给临床指导。

 

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氟喹诺酮类抗菌药物在儿童应用中的专家共识
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  1. [GetPortalCommentsPageByObjectIdResponse(id=2208830, encodeId=c95222088302d, content=填了表,还要下载这个那个,设置障碍,就是不能看文章,你的初心是什么?, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cb5734611, createdName=fanchengli6586, createdTime=Fri Jun 07 16:52:47 CST 2024, time=2024-06-07, status=1, ipAttribution=山东省), GetPortalCommentsPageByObjectIdResponse(id=278963, encodeId=6aba2e8963ad, content=国内对于儿童喹诺*类用药敬而远之.可以考虑逐渐用药?值得一看, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A255C84C7CC905B7A536F1089C7CFA96/100, createdBy=526a2034359, createdName=竹颜, createdTime=Tue Jan 16 07:24:42 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274186, encodeId=f07a2e41861b, content=非常好的文章.学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Dec 31 12:43:17 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274171, encodeId=08ae2e41719c, content=henhao, beContent=null, objectType=guider, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Dec 31 11:11:44 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274115, encodeId=6a312e411565, content=学习谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Dec 31 09:39:47 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2024-06-07 fanchengli6586 来自山东省

    填了表,还要下载这个那个,设置障碍,就是不能看文章,你的初心是什么?

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2208830, encodeId=c95222088302d, content=填了表,还要下载这个那个,设置障碍,就是不能看文章,你的初心是什么?, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cb5734611, createdName=fanchengli6586, createdTime=Fri Jun 07 16:52:47 CST 2024, time=2024-06-07, status=1, ipAttribution=山东省), GetPortalCommentsPageByObjectIdResponse(id=278963, encodeId=6aba2e8963ad, content=国内对于儿童喹诺*类用药敬而远之.可以考虑逐渐用药?值得一看, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A255C84C7CC905B7A536F1089C7CFA96/100, createdBy=526a2034359, createdName=竹颜, createdTime=Tue Jan 16 07:24:42 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274186, encodeId=f07a2e41861b, content=非常好的文章.学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Dec 31 12:43:17 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274171, encodeId=08ae2e41719c, content=henhao, beContent=null, objectType=guider, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Dec 31 11:11:44 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274115, encodeId=6a312e411565, content=学习谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Dec 31 09:39:47 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2018-01-16 竹颜

    国内对于儿童喹诺*类用药敬而远之.可以考虑逐渐用药?值得一看

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2208830, encodeId=c95222088302d, content=填了表,还要下载这个那个,设置障碍,就是不能看文章,你的初心是什么?, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cb5734611, createdName=fanchengli6586, createdTime=Fri Jun 07 16:52:47 CST 2024, time=2024-06-07, status=1, ipAttribution=山东省), GetPortalCommentsPageByObjectIdResponse(id=278963, encodeId=6aba2e8963ad, content=国内对于儿童喹诺*类用药敬而远之.可以考虑逐渐用药?值得一看, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A255C84C7CC905B7A536F1089C7CFA96/100, createdBy=526a2034359, createdName=竹颜, createdTime=Tue Jan 16 07:24:42 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274186, encodeId=f07a2e41861b, content=非常好的文章.学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Dec 31 12:43:17 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274171, encodeId=08ae2e41719c, content=henhao, beContent=null, objectType=guider, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Dec 31 11:11:44 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274115, encodeId=6a312e411565, content=学习谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Dec 31 09:39:47 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2017-12-31 天涯183

    非常好的文章.学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2208830, encodeId=c95222088302d, content=填了表,还要下载这个那个,设置障碍,就是不能看文章,你的初心是什么?, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cb5734611, createdName=fanchengli6586, createdTime=Fri Jun 07 16:52:47 CST 2024, time=2024-06-07, status=1, ipAttribution=山东省), GetPortalCommentsPageByObjectIdResponse(id=278963, encodeId=6aba2e8963ad, content=国内对于儿童喹诺*类用药敬而远之.可以考虑逐渐用药?值得一看, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A255C84C7CC905B7A536F1089C7CFA96/100, createdBy=526a2034359, createdName=竹颜, createdTime=Tue Jan 16 07:24:42 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274186, encodeId=f07a2e41861b, content=非常好的文章.学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Dec 31 12:43:17 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274171, encodeId=08ae2e41719c, content=henhao, beContent=null, objectType=guider, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Dec 31 11:11:44 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274115, encodeId=6a312e411565, content=学习谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Dec 31 09:39:47 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2017-12-31 1e0e5a1fm42(暂无匿称)

    henhao

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2208830, encodeId=c95222088302d, content=填了表,还要下载这个那个,设置障碍,就是不能看文章,你的初心是什么?, beContent=null, objectType=guider, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3cb5734611, createdName=fanchengli6586, createdTime=Fri Jun 07 16:52:47 CST 2024, time=2024-06-07, status=1, ipAttribution=山东省), GetPortalCommentsPageByObjectIdResponse(id=278963, encodeId=6aba2e8963ad, content=国内对于儿童喹诺*类用药敬而远之.可以考虑逐渐用药?值得一看, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A255C84C7CC905B7A536F1089C7CFA96/100, createdBy=526a2034359, createdName=竹颜, createdTime=Tue Jan 16 07:24:42 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274186, encodeId=f07a2e41861b, content=非常好的文章.学习了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Dec 31 12:43:17 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274171, encodeId=08ae2e41719c, content=henhao, beContent=null, objectType=guider, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Dec 31 11:11:44 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274115, encodeId=6a312e411565, content=学习谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Dec 31 09:39:47 CST 2017, time=2017-12-31, status=1, ipAttribution=)]
    2017-12-31 龙胆草

    学习谢谢分享

    0

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