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寨卡病毒是引起新生儿眼部病变元凶

2016-06-04 佚名 新华网

近期,科学家持续揭开寨卡病毒的神秘面纱。上个月,斯洛文尼亚的一个研究小组证实了寨卡病毒和新生儿先天性小头症的关联;上周,巴西研究人员又公布了两项最新研究成果,证实了今年2月医学界提出的另一个怀疑,即先天性小头症的出现往往还会伴随其他病症。 在大多数情况下,与先天性小头症一起出现的症状还有视觉神经系统病变和视网膜出血等多种眼部异常症状。因此,巴西研究人员提出,应该对患小头症的新生儿逐个进行眼部检查

近期,科学家持续揭开寨卡病毒的神秘面纱。上个月,斯洛文尼亚的一个研究小组证实了寨卡病毒和新生儿先天性小头症的关联;上周,巴西研究人员又公布了两项最新研究成果,证实了今年2月医学界提出的另一个怀疑,即先天性小头症的出现往往还会伴随其他病症。

在大多数情况下,与先天性小头症一起出现的症状还有视觉神经系统病变和视网膜出血等多种眼部异常症状。因此,巴西研究人员提出,应该对患小头症的新生儿逐个进行眼部检查,以便更好地进行治疗。

巴西研究小组的第一个研究成果,发表在5月26日的《JAMA眼科学》杂志上,揭示了易引发眼部疾病的两种情况,其中最重要的就是先天性小头症。在24名接受观察的婴儿中,有14名(约占58%)表现出了眼部问题。第二种情况是孕妇在怀孕初期表现出感染寨卡病毒的迹象。在14名接受观察的怀孕妇女中,有10名(约占71%)在怀孕初期表现出了病毒感染的症状。而这些怀孕女性在怀孕前和怀孕期间都没有结膜炎或葡萄膜炎等眼部疾病。这就排除掉了婴儿患眼部疾病的遗传因素。

第二个研究成果,发表在美国眼科医师协会官方会刊《眼科学》上,证实了第一个研究的结论,接受观察的3名患先天性小头症和眼部异常的婴儿都同时满足以上两种情况。第二个研究列出了完整的眼部异常症状的清单,在色素性视网膜炎和视神经萎缩的基础上,加上了眼底黄斑病变、视网膜出血等症状。这些症状可产生不同的结果,从轻微的视觉不适到完全失明都有可能,也可能出现几种病症叠加的现象。

根据巴西出生统计系统,患小头症的新生儿从2010年至2015年增加了20倍之多,最近几个月内约有4000名新出生的婴儿患有此症。

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    2016-08-05 huiwelcome
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    2016-06-05 沉心多思

    不错的文章,多学习

    0

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    2016-06-05 沉心多思

    不错的文章,多学习

    0

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巴西寨卡病毒毒株(ZIKVBR)可以通过小鼠的胎盘并导致包括小头畸形在内的发育缺陷。这些研究结果近日发表在《自然》杂志上,是首次通过动物实验模型证明巴西寨卡病毒毒株会导致出生缺陷。该论文同时也发现巴西寨卡病毒可以感染体外培养的人脑类器官,诱导细胞死亡并且破坏被称为皮质层的神经组织层。 最近巴西出生的畸形婴儿数目的增加被认为和一株源自亚洲的寨卡病毒毒株的暴发有关,病毒通过埃及伊蚊传

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