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JAHA:房颤对Takotsubo综合征患者结局的影响

2021-07-28 MedSci原创 MedSci原创

房颤(AF)是导致死亡的主要危险因素。尚未在大型患者队列中探究AF在Takotsubo综合征(TTS)患者中的患病率、临床相关性以及预后影响。

房颤(AF)是导致死亡的主要危险因素。尚未在大型患者队列中探究AF在Takotsubo综合征(TTS)患者中的患病率、临床相关性以及预后影响。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在调查TTS患者AF的患病率、临床相关性以及预后影响。TTS患者来自国际Takotsubo注册中心,这是一个跨国网络,包含了欧洲和美国的26个参与中心。根据受试者入院时是否存在AF将患者分为两类。

在1584名TTS患者中,112名(7.1%)TTS患者伴有AF。与非AF组相比,AF组的平均年龄较高(P<0.001),且女性较少(P=0.046)。AF组左心室射血分数显著降低(P=0.001),心源性休克更常见(P<0.001)。房颤组的住院死亡率(P<0.001)和长期死亡率(P<0.001)均较高。

多变量COX回归分析结果

多变量Cox回归分析发现AF与较高的长期死亡率独立相关(风险比为2.31;95%CI为1.50-3.55;P<0.001)。在入院时伴有AF的患者中,42%的患者在发生急性TTS事件之前没有AF病史,与有AF病史的患者相比,这些患者的院内和长期预后相当。
 
由此可见,在TTS患者中,入院时伴有AF与院内和长期死亡率增加显著相关。因此,应在未来的试验中评估抗心律失常药和/或心脏复律是否对伴有AF的TTS患者有益。

原始出处:

Ibrahim El‐Battrawy.et al.Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry.JAHA.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.119.014059

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    2021-07-30 ms3000001999514966

    理学记器

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    2021-07-30 zhaohui6731
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    2021-07-30 axin015
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    2021-07-28 心介

    房颤,临床上碰到很多哦

    0

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    2021-07-28 周小洋

    学习了

    0

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