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UEGW2017:中国门脉高压无创诊断研究组在欧洲消化疾病周作口头报告并获评Oral Paper Prize

2017-11-06 祁小龙 国际肝病

近日,在西班牙巴塞罗那举办的第25届欧洲消化疾病周(UEGW)上,来自南方医科大学南方医院的祁小龙教授代表中国门脉高压无创诊断研究组(CHESS)在欧洲肝病学会(EASL)组织的肝硬化及并发症会场报告了一项前瞻性多中心门脉高压无创诊断试验结果,该研究同时获评UEGW本会场唯一的Oral Paper Prize。

近日,在西班牙巴塞罗那举办的第25届欧洲消化疾病周(UEGW)上,来自南方医科大学南方医院的祁小龙教授代表中国门脉高压无创诊断研究组(CHESS)在欧洲肝病学会(EASL)组织的肝硬化及并发症会场报告了一项前瞻性多中心门脉高压无创诊断试验结果,该研究同时获评UEGW本会场唯一的Oral Paper Prize。

UEGW口头报告奖

在国际最新门脉高压指南Baveno IV和AASLD2016中,肝静脉压力梯度(HVPG)被推荐作为肝硬化门脉高压的诊断金标准,当HVPG大于10 mmHg时,提示患者存在临床显着性门脉高压(CSPH),这对于病情诊断、危险风层及干预疗效具有重要指导价值。然而,该检测技术为有创性,在我国绝大部分医疗中心尚未开展。

CHESS1701研究(NCT03138915)旨在利用影像组学技术建立并验证一种肝硬化门脉高压CSPH的无创诊断模型。该项前瞻性多中心试验由南方医院发起,联合解放军三〇二医院、北京世纪坛医院、北京佑安医院、湘雅三医院、邢台市人民医院、西南医科大学附属中医医院和中科院自动化研究所共同协作完成。研究在2016年8月至2017年9月间,连续入组符合条件的肝硬化门脉高压患者共370例,利用训练队列中222例数据的CT影像资料进行放射组学特征分析和LASSO建模,构建了包括11个CT纹理特征的诊断模型,随后在148例外部队列中前瞻性验证了模型的预测价值。目前,该无创模型已申请国际PCT,相关技术产品初步成型。

UEGW是欧洲规模最大且最具影响力的消化疾病会议,由EASL、EAES、EAGEN、ECCO、EDS、EFISDS、ESGE、ESP等16家欧洲消化疾病学会联合组织,本次第25届学术年会在西班牙巴塞罗那召开,共吸引来自116个国家的12810余名专家学者。

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    2018-05-11 feather89
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  5. 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  6. 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likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Mon Nov 06 23:37:03 CST 2017, time=2017-11-06, status=1, ipAttribution=)]
    2018-08-29 小几洁
  7. 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    2017-11-06 changjiu

    学习一下谢谢

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