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Diabetes Care:不同糖尿病状态个体的BMI与全因死亡率分析!

2017-04-12 xing.T MedSci原创

无论糖尿病的状态,其关系为U型曲线。在每一个年龄和性别群体中,随着糖尿病恶化,最低死亡率的最佳BMI范围逐渐升高。

近日,糖尿病领域权威杂志Diabetes Care上发表了一研究文章,研究人员旨在探讨正常血糖、空腹血糖受损(IFG)、新诊断糖尿病和已诊断糖尿病患者BMI与死亡率之间的相关性,以及确定各组与最低死亡率相关的BMI范围。

研究人员对12815006名成年人进行了前瞻性监测,直到2013年。糖尿病状态的定义如下:正常血糖(空腹血糖低于100mg/dL)、IFG(100-125mg/dL)、新诊断糖尿病(≥126mg/dL)和糖尿病(自我报告)。研究人员测定了受试者的体重指数(公斤/平方米)。调整混杂因素后计算了Cox模型风险比。

在平均随访10.5年期间,454546例男性和239877例女性发生了死亡。无论糖尿病状态、性别、年龄和吸烟史,研究人员观察到了U型相关性。死亡率最低的最佳的BMI(kg/m2)组为23.5-27.9(正常),25-27.9(IFG)、25-29.4(新诊断糖尿病)和26.5-29.4(糖尿病)。恶化的糖尿病状况导致最佳的BMI更高,在较低年龄受试者中,尤其是女性,更为突出。恶化的糖尿病状态和较高的死亡率之间的相关性在BMI越低的受试者越强,尤其是在年龄较少的受试者。考虑到相同的BMI,已诊断的糖尿病患者与新诊断的糖尿病患者相比死亡率更高,女性比男性更显著。

无论糖尿病的状态,其关系为U型曲线。在每一个年龄和性别群体中,随着糖尿病恶化,最低死亡率的最佳BMI范围逐渐升高。

原始出处:

Eun Young Lee,et al. BMI and All-Cause Mortality in Normoglycemia, Impaired Fasting Glucose, Newly Diagnosed Diabetes, and Prevalent Diabetes: A Cohort Study. Diabetes Care 2017. http://care.diabetesjournals.org/content/early/2017/04/05/dc16-1458

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  6. 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    2017-04-13 ylzr123

    好文,值得点赞,更值得收藏!慢慢领会学习的。

    0

  7. 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objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/iaqwic5175nrs2asVmGicNahCpBSxNUbSuA4vpeiazhWPdV79iaSIJsvMiaGECEouckrnOYc6073M9RbpNPL6qU9SdfB5BsicIqON4X/0, createdBy=f47f2017208, createdName=1e20390em99(暂无匿称), createdTime=Wed Apr 12 13:19:34 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186850, encodeId=6b091868500f, content=好好学习,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Wed Apr 12 09:44:14 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186848, encodeId=190c18684859, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Apr 12 09:42:44 CST 2017, time=2017-04-12, status=1, ipAttribution=)]
    2017-04-12 美蓝123

    这是说BMI不一定要控制在最低的意思吗?不同状态不用的BMI

    0

  8. 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GetPortalCommentsPageByObjectIdResponse(id=186848, encodeId=190c18684859, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Apr 12 09:42:44 CST 2017, time=2017-04-12, status=1, ipAttribution=)]
    2017-04-12 1e20390em99(暂无匿称)

    值得学习分享

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/iaqwic5175nrs2asVmGicNahCpBSxNUbSuA4vpeiazhWPdV79iaSIJsvMiaGECEouckrnOYc6073M9RbpNPL6qU9SdfB5BsicIqON4X/0, createdBy=f47f2017208, createdName=1e20390em99(暂无匿称), createdTime=Wed Apr 12 13:19:34 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186850, encodeId=6b091868500f, content=好好学习,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Wed Apr 12 09:44:14 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186848, encodeId=190c18684859, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Apr 12 09:42:44 CST 2017, time=2017-04-12, status=1, ipAttribution=)]
    2017-04-12 shaosai

    好好学习,涨知识

    0

  10. 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GetPortalCommentsPageByObjectIdResponse(id=186848, encodeId=190c18684859, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Wed Apr 12 09:42:44 CST 2017, time=2017-04-12, status=1, ipAttribution=)]
    2017-04-12 Chongyang Zhang

    签到学习了很多。

    0

相关资讯

Diabetes Care:连续血糖监测对1型糖尿病患者生活质量指标的影响!

由此可见,CGM可以显著改善成年糖尿病患者糖尿病特异性QOL(即糖尿病困扰、降血糖信心),但与糖尿病非特异性QOL指标(即幸福感、健康状况)无关。CGM满意度与大多数的QOL结果相关,但与血糖结果无关。

KIDNEY INT:糖尿病血液透析患者糖化血红蛋白水平分布及其与死亡率的关系!

在日本与西方国家报道的糖尿病血液透析患者HbA1c水平差异很大。因此,该研究结果强调了针对种族和国家的血糖控制指南的重要性。

Circ-Cardiovasc Inte:2型糖尿病患者PCI后血糖控制状况及长期临床结局!

经皮冠状动脉介入治疗后2年测得HbA1c<7与MACCE发生率降低相关。该研究的数据表明经皮冠状动脉介入术后2年HbA1c水平升高可以识别不良事件风险增加的人群,尤其是重复血运重建的患者。

Diabetes Technol Ther:禁食法可以治疗糖尿病吗?风险有哪些?

【禁食对糖尿病患者的风险:胰岛素泵VS人工注射】在此前的研究中,科学家曾称“模拟禁食”法可以逆转糖尿病的治疗。我们都知道,在沙特等国,存在着斋戒月,在此期间人们会完全禁食,包括糖尿病患者。近期,来自沙特阿拉伯的一支研究团队科学人员对1型糖尿病患者在斋戒禁食期间的风险以及各种日常护理措施进行了对比,其中包括使用胰岛素泵和每日多次注射胰岛素这两种不同的情况下,血糖的控制,低血糖症的比例以及高血糖症的区

Hypertension:高血压伴2型糖尿病患者的总体/心血管风险如何?

由此可见,整体的预防应包括减少酒精和烟草消耗量、改善压力、教育水平和身体活动。

英国拉夫堡大学研究发现 :常洗热水澡预防糖尿病

糖尿病是一组由遗传和环境等多种病因引起以慢性高血糖为特征的代谢性疾病群。由于胰岛素分泌相对或绝对不足;或胰岛素作用缺陷引起糖、蛋白质、脂肪、水和电解质等一系列代谢紊乱。持续高血糖是基本特征。久病可引起多系统损害,导致眼、肾、神经、及心脑血管、下肢等器官的慢性并发症。病情严重或应激时可发生急性代谢紊乱如酮症酸中毒、高渗昏迷、乳酸性酸中毒而威胁生命,常易并发化脓性感染、尿路感染、肺结核等。英国拉夫堡大

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