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Am J Clin Nutr:吃鸡蛋会不会增加糖尿病风险?

2016-01-09 Seven L 译 MedSci原创

先前关于鸡蛋摄入量和2型糖尿病风险间的观察性研究得出的结论不一致。鸡蛋是蛋白质和微量元素的良好来源且不贵,因此很有必有探究清楚鸡蛋和糖尿病间的联系。研究者通过检索PubMed、Ovid、Cochrane、Google Scholar等数据库中关于两者间联系的前瞻性研究,进行荟萃分析鸡蛋摄入量和糖尿病风险间联系,同时评估剂量-反应关系。该荟萃分析最终纳入了12个队列,涉及219,979名参与者,89

先前关于鸡蛋摄入量和2型糖尿病风险间的观察性研究得出的结论不一致。鸡蛋是蛋白质和微量元素的良好来源且不贵,因此很有必有探究清楚鸡蛋和糖尿病间的联系。

研究者通过检索PubMed、Ovid、Cochrane、Google Scholar等数据库中关于两者间联系的前瞻性研究,进行荟萃分析鸡蛋摄入量和糖尿病风险间联系,同时评估剂量-反应关系。

该荟萃分析最终纳入了12个队列,涉及219,979名参与者,8911名糖尿病患者。鸡蛋摄入量最高组与摄入量最低组比较,固定效应模型分析下RR=1.09 (95% CI: 0.99, 1.20),随机效应模型下分析RR=1.06 (95% CI: 0.86, 1.30),各研究间异质性I2 = 73.6%(P < 0.001)。根据地理区域对参与者进行分层后发现,美国进行了的研究合并后表明,鸡蛋摄入量最高组比鸡蛋摄入量最低组糖尿病风险高39%(95% CI: 21%, 60%),不过除美国之外其他地区的研究没有发现风险的升高 (RR = 0.89; 95% CI: 0.79, 1.02(随机效应模型), P < 0.001(美国与非美国比较))。分析剂量-反应关系反应时发现美国的研究表明,每周鸡蛋摄入量在3个或以上,糖尿病风险增加,而非美国的研究没有发现之间的联系。

该荟萃分析表明,鸡蛋摄入量与糖尿病风险间没有关系,但是美国的研究表明每周吃鸡蛋3个或以上,就会导致糖尿病风险的轻度增加。

原始出处:

Djoussé L, Khawaja OA,et al.Egg consumption and risk of type 2 diabetes: a meta-analysis of prospective studies.Am J Clin Nutr. 2016 Jan 6. pii: ajcn119933. [Epub ahead of print]


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  1. [GetPortalCommentsPageByObjectIdResponse(id=58678, encodeId=4697586e85a, content=看来还是热量摄入的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=168, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG56122759380B63136.jpg, createdBy=aa691654054, createdName=Dirty Donkey, createdTime=Thu Jan 21 16:15:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58335, encodeId=95f858335fa, content=头回听说鸡蛋和DM有关系,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue Jan 19 09:31:00 CST 2016, time=2016-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58179, encodeId=4908581e9bd, content=适量, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=77e41648823, createdName=miaotao, createdTime=Mon Jan 18 09:32:00 CST 2016, time=2016-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57085, encodeId=8a5d5e085c9, content=多吃一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160113/IMG569619FEB03536446.jpg, createdBy=85f81678980, createdName=Lynee劲飞扬, createdTime=Wed Jan 13 22:30:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57056, encodeId=dcf65e056a0, content=鸡蛋和糖尿病?, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/1f886e5d12c4637fe453ab919f018749/cb630129a57260ee2ad4a625e102da72.jpg, createdBy=c1d01679078, createdName=circlegirl, createdTime=Wed Jan 13 19:46:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56430, encodeId=52cf56430b4, content=不能多吃, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56431, encodeId=368e5643186, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=)]
    2016-01-21 Dirty Donkey

    看来还是热量摄入的问题

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=58678, encodeId=4697586e85a, content=看来还是热量摄入的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=168, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG56122759380B63136.jpg, createdBy=aa691654054, createdName=Dirty Donkey, createdTime=Thu Jan 21 16:15:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58335, encodeId=95f858335fa, content=头回听说鸡蛋和DM有关系,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue Jan 19 09:31:00 CST 2016, time=2016-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58179, encodeId=4908581e9bd, content=适量, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=77e41648823, createdName=miaotao, createdTime=Mon Jan 18 09:32:00 CST 2016, time=2016-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57085, encodeId=8a5d5e085c9, content=多吃一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160113/IMG569619FEB03536446.jpg, createdBy=85f81678980, createdName=Lynee劲飞扬, createdTime=Wed Jan 13 22:30:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57056, encodeId=dcf65e056a0, content=鸡蛋和糖尿病?, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/1f886e5d12c4637fe453ab919f018749/cb630129a57260ee2ad4a625e102da72.jpg, createdBy=c1d01679078, createdName=circlegirl, createdTime=Wed Jan 13 19:46:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56430, encodeId=52cf56430b4, content=不能多吃, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56431, encodeId=368e5643186, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=)]
    2016-01-19 ssummer

    头回听说鸡蛋和DM有关系,学习了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=58678, encodeId=4697586e85a, content=看来还是热量摄入的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=168, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG56122759380B63136.jpg, createdBy=aa691654054, createdName=Dirty Donkey, createdTime=Thu Jan 21 16:15:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58335, encodeId=95f858335fa, content=头回听说鸡蛋和DM有关系,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue Jan 19 09:31:00 CST 2016, time=2016-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58179, encodeId=4908581e9bd, content=适量, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=77e41648823, createdName=miaotao, createdTime=Mon Jan 18 09:32:00 CST 2016, time=2016-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57085, encodeId=8a5d5e085c9, content=多吃一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160113/IMG569619FEB03536446.jpg, createdBy=85f81678980, createdName=Lynee劲飞扬, createdTime=Wed Jan 13 22:30:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57056, encodeId=dcf65e056a0, content=鸡蛋和糖尿病?, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/1f886e5d12c4637fe453ab919f018749/cb630129a57260ee2ad4a625e102da72.jpg, createdBy=c1d01679078, createdName=circlegirl, createdTime=Wed Jan 13 19:46:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56430, encodeId=52cf56430b4, content=不能多吃, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56431, encodeId=368e5643186, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=)]
    2016-01-18 miaotao

    适量

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=58678, encodeId=4697586e85a, content=看来还是热量摄入的问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=168, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG56122759380B63136.jpg, createdBy=aa691654054, createdName=Dirty Donkey, createdTime=Thu Jan 21 16:15:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58335, encodeId=95f858335fa, content=头回听说鸡蛋和DM有关系,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue Jan 19 09:31:00 CST 2016, time=2016-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58179, encodeId=4908581e9bd, content=适量, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=77e41648823, createdName=miaotao, createdTime=Mon Jan 18 09:32:00 CST 2016, time=2016-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57085, encodeId=8a5d5e085c9, content=多吃一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160113/IMG569619FEB03536446.jpg, createdBy=85f81678980, createdName=Lynee劲飞扬, createdTime=Wed Jan 13 22:30:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57056, encodeId=dcf65e056a0, content=鸡蛋和糖尿病?, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://login.medsci.cn/upload/avatar/1f886e5d12c4637fe453ab919f018749/cb630129a57260ee2ad4a625e102da72.jpg, createdBy=c1d01679078, createdName=circlegirl, createdTime=Wed Jan 13 19:46:00 CST 2016, time=2016-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56430, encodeId=52cf56430b4, content=不能多吃, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56431, encodeId=368e5643186, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Tue Jan 12 17:51:00 CST 2016, time=2016-01-12, status=1, ipAttribution=)]
    2016-01-13 Lynee劲飞扬

    多吃一个

    0

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    2016-01-13 circlegirl

    鸡蛋和糖尿病?

    0

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    2016-01-12 xyfg98

    不能多吃

    0

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    2016-01-12 xyfg98

    赞一个

    0

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