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Dermatol Ther:点阵CO2激光联合局部抗真菌是一种治疗甲癣安全且有效的方法

2020-12-12 MedSci原创 MedSci原创

甲癣是影响患者健康和生活质量的重要医学疾病。近日,一项研究是旨在比较CO2激光联合外用替康唑VS仅用CO2激光VS单用外用替康唑对甲癣的疗效,研究结果已在线发表于Dermatol Ther。

甲癣是影响患者健康和生活质量的重要医学疾病。近日,一项研究是旨在比较CO2激光联合外用替康唑VS仅用CO2激光VS单用外用替康唑对甲癣的疗效,研究结果已在线发表于Dermatol Ther。

研究共纳入了120例甲癣患者,随机分为三组。A组患者采用点阵式CO2激光治疗,然后外用噻康唑28%,共5次,间隔3周。B组患者仅用点阵CO2激光治疗5次,间隔3周。C组患者仅外用噻康唑28%治疗16周。分析三组患者的临床效果、KOH检查及患甲培养情况。

 

结果显示,最后一个疗程后一个月,A组、B组和C组完全临床改善的患者比例分别为55%,30%和25%,组间差异显著。在治疗后的KOH试验和培养方面,三组之间同样存在显著差异。

综上所述,该研究结果表明,点阵CO2激光联合局部抗真菌是一种安全有效的治疗甲癣的方法。

 

原始出处:

 

Amr Mohamed Zaki, Hamed Mohamed Abdo, et al., Fractional CO 2 laser plus topical antifungal versus fractional CO 2 laser versus topical antifungal in the treatment of onychomycosis. Dermatol Ther. 2020 Jan;33(1):e13155. doi: 10.1111/dth.13155.

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    2021-01-11 amy0563
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    2020-12-14 oliver169
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    2020-12-14 zhaojie88
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    2020-12-14 chg122
  5. [GetPortalCommentsPageByObjectIdResponse(id=1775759, encodeId=70941e757590b, content=<a href='/topic/show?id=19e45556efa' target=_blank style='color:#2F92EE;'>#抗真菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55567, encryptionId=19e45556efa, topicName=抗真菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=596c38798743, createdName=amy0563, createdTime=Mon Jan 11 19:26:47 CST 2021, time=2021-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279773, encodeId=6e9612e9773d5, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1353808, encodeId=ca471353808fe, content=<a href='/topic/show?id=dddce266537' target=_blank style='color:#2F92EE;'>#真菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72665, encryptionId=dddce266537, topicName=真菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1406010, encodeId=de0d1406010be, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907378, encodeId=842790e37882, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Dec 12 20:10:11 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907342, encodeId=7c9390e3424d, content=看起来还不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Dec 12 18:00:00 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907334, encodeId=4b2a90e3342d, content=<a href='/topic/show?id=e46769928da' target=_blank style='color:#2F92EE;'>#甲癣#</a>最佳的治疗方法就是使用杨森公司的<a href='/topic/show?id=1e541040e532' target=_blank style='color:#2F92EE;'>#斯皮仁诺#</a>,即伊曲康唑,效果十分好,根本不需要这种治疗,那种治疗的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69928, encryptionId=e46769928da, topicName=甲癣), TopicDto(id=104075, encryptionId=1e541040e532, topicName=斯皮仁诺)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=lifefamily, createdTime=Sat Dec 12 17:52:44 CST 2020, time=2020-12-12, status=1, ipAttribution=)]
    2020-12-12 瓜虫

    学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1775759, encodeId=70941e757590b, content=<a href='/topic/show?id=19e45556efa' target=_blank style='color:#2F92EE;'>#抗真菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55567, encryptionId=19e45556efa, topicName=抗真菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=596c38798743, createdName=amy0563, createdTime=Mon Jan 11 19:26:47 CST 2021, time=2021-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279773, encodeId=6e9612e9773d5, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1353808, encodeId=ca471353808fe, content=<a href='/topic/show?id=dddce266537' target=_blank style='color:#2F92EE;'>#真菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72665, encryptionId=dddce266537, topicName=真菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1406010, encodeId=de0d1406010be, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907378, encodeId=842790e37882, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Dec 12 20:10:11 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907342, encodeId=7c9390e3424d, content=看起来还不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Dec 12 18:00:00 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907334, encodeId=4b2a90e3342d, content=<a href='/topic/show?id=e46769928da' target=_blank style='color:#2F92EE;'>#甲癣#</a>最佳的治疗方法就是使用杨森公司的<a href='/topic/show?id=1e541040e532' target=_blank style='color:#2F92EE;'>#斯皮仁诺#</a>,即伊曲康唑,效果十分好,根本不需要这种治疗,那种治疗的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69928, encryptionId=e46769928da, topicName=甲癣), TopicDto(id=104075, encryptionId=1e541040e532, topicName=斯皮仁诺)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=lifefamily, createdTime=Sat Dec 12 17:52:44 CST 2020, time=2020-12-12, status=1, ipAttribution=)]
    2020-12-12 易水河

    看起来还不错

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1775759, encodeId=70941e757590b, content=<a href='/topic/show?id=19e45556efa' target=_blank style='color:#2F92EE;'>#抗真菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55567, encryptionId=19e45556efa, topicName=抗真菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=596c38798743, createdName=amy0563, createdTime=Mon Jan 11 19:26:47 CST 2021, time=2021-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279773, encodeId=6e9612e9773d5, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1353808, encodeId=ca471353808fe, content=<a href='/topic/show?id=dddce266537' target=_blank style='color:#2F92EE;'>#真菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72665, encryptionId=dddce266537, topicName=真菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1406010, encodeId=de0d1406010be, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Mon Dec 14 08:26:47 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907378, encodeId=842790e37882, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=568f2273884, createdName=瓜虫, createdTime=Sat Dec 12 20:10:11 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907342, encodeId=7c9390e3424d, content=看起来还不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Dec 12 18:00:00 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907334, encodeId=4b2a90e3342d, content=<a href='/topic/show?id=e46769928da' target=_blank style='color:#2F92EE;'>#甲癣#</a>最佳的治疗方法就是使用杨森公司的<a href='/topic/show?id=1e541040e532' target=_blank style='color:#2F92EE;'>#斯皮仁诺#</a>,即伊曲康唑,效果十分好,根本不需要这种治疗,那种治疗的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69928, encryptionId=e46769928da, topicName=甲癣), TopicDto(id=104075, encryptionId=1e541040e532, topicName=斯皮仁诺)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=lifefamily, createdTime=Sat Dec 12 17:52:44 CST 2020, time=2020-12-12, status=1, ipAttribution=)]
    2020-12-12 lifefamily

    #甲癣#最佳的治疗方法就是使用杨森公司的#斯皮仁诺#,即伊曲康唑,效果十分好,根本不需要这种治疗,那种治疗的。

    0

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