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Ann Rheum Dis:大血管炎中MR血管造影与18F-氟脱氧葡萄糖正电子发射断层扫描的比较

2018-04-20 xiangting MedSci原创

在评估LVV时,MRA和PET可以提供独特和补充信息。MRA更好地捕捉疾病程度,PET扫描更适合评估血管活动性。

这项研究旨在评估磁共振血管造影(MRA)与18F-脱氧葡萄糖正电子发射断层扫描(PET)对大血管血管炎(LVV)疾病程度和疾病活动解释的一致性,并确定影像学与临床评估之间的关联。

将患有巨细胞动脉炎(GCA)、Takayasu动脉炎(TAK)的患者和对照纳入前瞻性观察队列。同时进行影像学和临床评估,彼此不知情。一致性是通过百分比一致性、Cohen k和McNemar检验来评估的。多因素logistic回归分析确定了与PET扫描活动相关的MRA特征。

84名患者(GCA = 35; TAK = 30;对照= 19)组成了133对配对研究。MRA与PET之间的疾病程度的一致性为966(60%)动脉区域中有580个,Cohen k= 0.22。在有分歧的386个区域,MRA比PET在更多的区域表现出疾病(304 vs 82,p <0.01)。MRA与PET之间疾病活动的一致性是90项(68%),Cohen k= 0.30。在有分歧的研究中,MRA在23项研究中显示活动性,PET在20项研究中显示活动性(p= 0.76)。MRA上的水肿和壁厚与PET扫描活动性独立相关。临床状态与PET的疾病活动性相关(p <0.01),而不是MRA(p = 0.70),而35/69(51%)例临床缓解的LVV患者的MRA和PET同时存在活动性。

在评估LVV时,MRA和PET可以提供独特和补充信息。MRA更好地捕捉疾病程度,PET扫描更适合评估血管活动性。在LVV的病程中临床和基于影像的评估通常不相关。

原始出处:

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    2018-08-17 kkunny
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    2018-04-22 sodoo
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    2018-04-20 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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