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J Dent Res：全新牙科原型复合材料的机械和生物学评估

2018-09-23 lishiting MedSci原创

复合材料添加物
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现代牙科复合修复材料聚合物组分的分解会损害它们的寿命，而来自这些材料的可浸出化合物又具有细胞毒性。因此，需要研发一种全新的具有更长使用寿命，同时确保任何可浸出复合物对细胞没有任何伤害的复合材料。为了达到此种要求，作者团队开发了基于硫醇烯聚合反应和烯丙基硫化物的加成-断裂链转移化学品，以提供具有低收缩和低收缩应力的交联聚合物树脂。

现代牙科复合修复材料聚合物组分的分解会损害它们的寿命，而来自这些材料的可浸出化合物又具有细胞毒性。因此，需要研发一种全新的具有更长使用寿命，同时确保任何可浸出复合物对细胞没有任何伤害的复合材料。为了达到此种要求，作者团队开发了基于硫醇烯聚合反应和烯丙基硫化物的加成-断裂链转移化学品，以提供具有低收缩和低收缩应力的交联聚合物树脂。在过去，用做牙科复合材料充填剂的主要为生物惰性玻璃。在作者团队研发的几种原型复合材料中，添加的是氟磷灰石(FA)晶体，它类似于釉质晶体并且具有生活活性。这些全新的原型复合材料以类似添加物为甲基丙烯酸酯基双酚A二缩水甘油醚二甲基丙烯酸酯/三甘醇二甲基丙烯酸酯（bisGMA / TEGDMA）复合材料为基准进行测试，以确定其细胞毒性，机械性能，生物膜形成和氟化物释放的情况。结果显示，所有复合材料的可浸出物在pH 7时对牙髓干细胞无毒性。与类似于bisGMA/TEGDMA添加物相比，所有仅添加玻璃的原型复合材料均有韧性明显增加的趋势。而仅添加玻璃的原型复合材料的其他机械特质与bisGMA/TEGDMA复合材料相当。加入FA会降低原型及bisGMA/TEGDMA复合材料

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    2019-08-10 ms4964546379600229

    #复合材料#

    0

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    2018-09-27 Jackie Li

    学习

    0

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    2018-09-25 12498c32m74暂无昵称

    #生物学#

    0

  4. 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time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346409, encodeId=04113464091f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Sep 24 09:12:03 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-25 xzw115

    #牙科#

    0

  5. 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time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346409, encodeId=04113464091f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Sep 24 09:12:03 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 Y—xianghai

    学习了长知识

    0

  6. 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time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346409, encodeId=04113464091f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Sep 24 09:12:03 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 Y—xianghai

    学习了长知识

    0

  7. 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time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346409, encodeId=04113464091f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Sep 24 09:12:03 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 Y—xianghai

    学习了长知识

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2054521, encodeId=a260205452153, content=<a href='/topic/show?id=517c42615ef' target=_blank style='color:#2F92EE;'>#复合材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42615, encryptionId=517c42615ef, topicName=复合材料)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Sat Aug 10 13:04:00 CST 2019, time=2019-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346975, encodeId=c1fb3469e5fd, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346409, encodeId=04113464091f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Sep 24 09:12:03 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 Y—xianghai

    学习了长知识

    0

  9. 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time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346409, encodeId=04113464091f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Sep 24 09:12:03 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 Y—xianghai

    学习了长知识

    0

  10. 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time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346409, encodeId=04113464091f, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Sep 24 09:12:03 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 Y—xianghai

    学习了长知识

    0

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本研究旨在通过在Cr纳米颗粒（Cr NPs）的存在下通过聚邻氯苯胺的原位化学氧化制备导电聚邻氯苯胺/铬纳米复合材料（POC/Cr NCs）。 Cr纳米填料的负载百分比在POC基质中变化，以研究Cr纳米颗粒对纳米复合材料性能的影响。通过扫描电子显微镜、傅里叶变换红外光谱和紫外-可见光谱分析检测POC及其复合材料的组成、结构和形态。通过对大肠杆菌和枯草芽孢杆菌的扩散法评价POC及其复合材料的抗菌潜力。

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