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JAHA:经导管主动脉瓣置换术后高度房室传导阻滞的发生率和预测因素

2021-05-08 MedSci原创 MedSci原创

在一级房室传导阻滞或右束支传导阻滞、新发左束支传导阻滞和自扩张瓣膜患者中,延迟性HAVB发生率较高。这些数据为根据围手术期心电图结果的最佳监测和起搏策略提供了新视角。

经导管主动脉瓣置换术(TAVR)后高度房室传导阻滞(HAVB)当前的发生率尚未明确。围手术期监测和起搏策略仍存在争议。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在阐明当前TAVR前后HAVB的发生率,并明确延迟HAVB事件的预测因素。

在2012年2月至2019年6月期间,研究人员对单个中心接受TAVR的连续就诊患者回顾性地评估了30天内HAVB,并排除了既往有主动脉瓣置换、永久性起搏器(PPM)或转换为手术置换的患者。研究人员进行了多变量logistic回归以评估延迟性HAVB(TAVR后24小时后发作)的预测因子。

本研究共纳入了953位患者。153例(16.1%)患者发生HAVB。排除在TAVR后放置预防性PPM的患者后,延迟性HAVB的发生率为33/882(3.7%)。与延迟性HAVB独立相关的变量包括基线时一级房室传导阻滞或右束支传导阻滞、自扩张阀和新的左束支传导阻滞。40例患者发生术中短暂性HAVB,包括16例复发性HAVB患者和6例进行PPM植入而未复发的患者。130例(13.6%)患者因HAVB放置PPM(自膨胀阀为23.7%,而球囊可膨胀阀为11.9%;P<0.001)。8例(0.8%)患者在30天前死亡,其中1例原因不明。

由此可见,在一级房室传导阻滞或右束支传导阻滞、新发左束支传导阻滞和自扩张瓣膜患者中,延迟性HAVB发生率较高。这些数据为根据围手术期心电图结果的最佳监测和起搏策略提供了新视角

原始出处:

Bassim El‐Sabawi.et al.Temporal Incidence and Predictors of High‐Grade Atrioventricular Block After Transcatheter Aortic Valve Replacement.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.020033

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  5. 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href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268526, encodeId=909d1268526c8, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1332792, encodeId=3c5d1332e924c, content=<a href='/topic/show?id=1dd6231822d' target=_blank style='color:#2F92EE;'>#主动脉瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23182, encryptionId=1dd6231822d, topicName=主动脉瓣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367229, encodeId=1476136e22928, content=<a href='/topic/show?id=b6222320322' target=_blank style='color:#2F92EE;'>#主动脉瓣置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23203, encryptionId=b6222320322, topicName=主动脉瓣置换术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b24249, createdName=medsci246, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415743, encodeId=bea41415e43b7, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
    2022-02-05 yxch48
  6. 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  7. 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href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268526, encodeId=909d1268526c8, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1332792, encodeId=3c5d1332e924c, content=<a href='/topic/show?id=1dd6231822d' target=_blank style='color:#2F92EE;'>#主动脉瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23182, encryptionId=1dd6231822d, topicName=主动脉瓣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367229, encodeId=1476136e22928, content=<a href='/topic/show?id=b6222320322' target=_blank style='color:#2F92EE;'>#主动脉瓣置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23203, encryptionId=b6222320322, topicName=主动脉瓣置换术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b24249, createdName=medsci246, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415743, encodeId=bea41415e43b7, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Mon May 10 01:20:10 CST 2021, time=2021-05-10, status=1, ipAttribution=)]
    2021-05-10 zhaohui6731
  8. 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  9. 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  10. 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