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Cancer Causes and Control:绝经后女性2型糖尿病与胃肠肿瘤有关

2012-06-05 魏冬 医学论坛网

     美国研究人员5月24日在线发表于《癌症病因与控制》(Cancer Causes and Control)一项研究表明,在绝经后女性中,2型糖尿病与肝、胰腺、结肠和直肠癌风险显著升高有关。   该研究对参与女性健康倡议(WHI)的145765名50~79岁的绝经后女性进行了为期10.3年的随访,并采用考克斯(Cox)比例风险回归模型分析了胃肠肿瘤与糖尿病的

  inserted image

  美国研究人员5月24日在线发表于《癌症病因与控制》(Cancer Causes and Control)一项研究表明,在绝经后女性中,2型糖尿病与肝、胰腺、结肠和直肠癌风险显著升高有关。

  该研究对参与女性健康倡议(WHI)的145765名50~79岁的绝经后女性进行了为期10.3年的随访,并采用考克斯(Cox)比例风险回归模型分析了胃肠肿瘤与糖尿病的相关性。

  结果显示,入组时已确诊的糖尿病与肝[风险比(HR)=2.97,95%可信区间(CI)=1.66~5.32]、胰腺(HR=1.62,95%CI=1.15~2.30)、结肠(HR=1.38,95%CI=1.14~1.66)和直肠癌风险(HR=1.87,95%CI=1.22~2.85)升高相关。

  糖尿病严重度似乎与肝、胰腺和直肠而非结肠癌风险的相关性更强。

  糖尿病与胆管、食管和胃癌无显著相关性。

      

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    2012-06-07 dongjia2015
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