Baidu
map

EMAS立场声明:维生素D和绝经后妇女健康共识

2012-02-17 MedSci MedSci原创

 维生素D缺乏不仅与骨质疏松症相关,还与心血管疾病、糖尿病、癌症、感染和神经变性疾病相关。尽管已有强有力的证据显示 维生素D对骨骼有影响,但维生素D对非骨骼方面转归的影响目前仍缺乏大型的前瞻性研究结果。欧洲更年期和男性更年期学会(EMAS)专家组对"维生素D在绝经妇女中的作用"作了一项立场声明,并发表于2012年1月《欧洲更年期杂志》。(Maturitas.2012-01;71(1):83-8.)

 维生素D缺乏不仅与骨质疏松症相关,还与心血管疾病、糖尿病、癌症、感染和神经变性疾病相关。尽管已有强有力的证据显示 维生素D对骨骼有影响,但维生素D对非骨骼方面转归的影响目前仍缺乏大型的前瞻性研究结果。欧洲更年期和男性更年期学会(EMAS)专家组对"维生素D在绝经妇女中的作用"作了一项立场声明,并发表于2012年1月《欧洲更年期杂志》(Maturitas.2012-01;71(1):83-8.)

  根据文献回顾和专家意见共识,EMAS专家组得出了如下结果和结论:

  1. 维生素D的天然来源主要是通过阳光照射刺激皮肤合成,饮食来源较少,如富含脂肪的鱼、蛋和牛奶等动物性食物为主的饮食。

  2. 尽管目前国际上尚未达成共识,但通过测定血清中25-羟基维生素D [25(OH)D]的浓度可确定体内 VD状态。25(OH)D理想的血清浓度范围是30~90(ng/mL)[75–225(nmol/L)]。

  3. 25(OH)D血清浓度随季节(冬季较低)、纬度、海拔高度、空气污染和皮肤色素沉着、防晒霜的使用及衣物遮盖而波动。

  4. 出现低血清25(OH)D浓度的危险因素包括:肥胖,吸收不良综合征,药物使用(如抗惊厥剂,抗逆转录病毒药物),皮肤老化,较少在太阳下照晒及居住于养老院。

  5. 强化食品不一定能提供足够的维生素D; 夏天中午有规律地在太阳下照晒(不使用防晒霜)15分钟,每周3~4次,可产生健康的血清25(OH)D水平;
  6. 每日推荐的维生素D供给量从600IU/d(国际单位/天)增至800IU/d(≥71岁的老人);可采用维生素D2或D3进行补充,根据使用剂量及是否存在合并症如肾病等情况进行监测。

  EMAS专家组给出的具体建议如下:

   卫生专业人员应该意识到,维生素D缺乏或不足是常见的,可能会影响到欧洲的70%人口(包括那些生活在阳光明媚的地区的人)。

   健康的绝经后妇女可以通过阳光照射(15分/天,3-4次/周)或补充维生素D(800-1000 IU /天),即可得到充足的血药浓度。

   低血清25(OH)D水平的妇女,维生素D的补充剂量应为4000-10000 IU /天,才能达到足够的水平。

  • 有病态肥胖(前、后胃肠搭桥手术)、吸收不良综合征、肝或肾脏疾病的妇女,需要定制具体剂量的维生素D补充剂。

  维生素D缺乏症与骨质疏松症和/或以前偶然发生的骨折相关,此类妇女应该补充足够量的维生素D(如果没有低血清维生素D水平的相关风险因素的话,应达到800-1200 IU /天),同时需要进行明确的骨保护治疗。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=4208, encodeId=1945420803, content=Ab fab my gdoloy man., beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=ankita, createdTime=Sun Apr 22 18:04:00 CST 2012, time=2012-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256965, encodeId=abdf1256965ec, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1317178, encodeId=d793131e17872, content=<a href='/topic/show?id=74916e0414' target=_blank style='color:#2F92EE;'>#EMA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6704, encryptionId=74916e0414, topicName=EMA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331989, encodeId=786a13319892a, content=<a href='/topic/show?id=0ab6e8887cc' target=_blank style='color:#2F92EE;'>#绝经后妇女#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78887, encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631464, encodeId=57ae1631464d9, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=)]
    2012-04-22 ankita

    Ab fab my gdoloy man.

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=4208, encodeId=1945420803, content=Ab fab my gdoloy man., beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=ankita, createdTime=Sun Apr 22 18:04:00 CST 2012, time=2012-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256965, encodeId=abdf1256965ec, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1317178, encodeId=d793131e17872, content=<a href='/topic/show?id=74916e0414' target=_blank style='color:#2F92EE;'>#EMA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6704, encryptionId=74916e0414, topicName=EMA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331989, encodeId=786a13319892a, content=<a href='/topic/show?id=0ab6e8887cc' target=_blank style='color:#2F92EE;'>#绝经后妇女#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78887, encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631464, encodeId=57ae1631464d9, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=4208, encodeId=1945420803, content=Ab fab my gdoloy man., beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=ankita, createdTime=Sun Apr 22 18:04:00 CST 2012, time=2012-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256965, encodeId=abdf1256965ec, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1317178, encodeId=d793131e17872, content=<a href='/topic/show?id=74916e0414' target=_blank style='color:#2F92EE;'>#EMA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6704, encryptionId=74916e0414, topicName=EMA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331989, encodeId=786a13319892a, content=<a href='/topic/show?id=0ab6e8887cc' target=_blank style='color:#2F92EE;'>#绝经后妇女#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78887, encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631464, encodeId=57ae1631464d9, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=)]
    2012-02-19 fengyi812
  4. [GetPortalCommentsPageByObjectIdResponse(id=4208, encodeId=1945420803, content=Ab fab my gdoloy man., beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=ankita, createdTime=Sun Apr 22 18:04:00 CST 2012, time=2012-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256965, encodeId=abdf1256965ec, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1317178, encodeId=d793131e17872, content=<a href='/topic/show?id=74916e0414' target=_blank style='color:#2F92EE;'>#EMA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6704, encryptionId=74916e0414, topicName=EMA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331989, encodeId=786a13319892a, content=<a href='/topic/show?id=0ab6e8887cc' target=_blank style='color:#2F92EE;'>#绝经后妇女#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78887, encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631464, encodeId=57ae1631464d9, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=4208, encodeId=1945420803, content=Ab fab my gdoloy man., beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=ankita, createdTime=Sun Apr 22 18:04:00 CST 2012, time=2012-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256965, encodeId=abdf1256965ec, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1317178, encodeId=d793131e17872, content=<a href='/topic/show?id=74916e0414' target=_blank style='color:#2F92EE;'>#EMA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6704, encryptionId=74916e0414, topicName=EMA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331989, encodeId=786a13319892a, content=<a href='/topic/show?id=0ab6e8887cc' target=_blank style='color:#2F92EE;'>#绝经后妇女#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78887, encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631464, encodeId=57ae1631464d9, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Sun Feb 19 14:13:00 CST 2012, time=2012-02-19, status=1, ipAttribution=)]
    2012-02-19 zxxiang

相关资讯

EMAS发表VitD与绝经后健康的声明

  最近,欧洲男女更年期协会(EMAS)就维生素D(VD)与绝经后健康问题发表了立场声明,该声明发表在《欧洲更年期杂志》【Maturitas 71 (2012) 83– 88】。   该声明强调:    VD充足时不必使用强化食品;   夏天中午有规律地在太阳下照晒(不使用防晒霜)15分钟,每周3~4次,可产生健康的血清25(OH)D水平;   每日

Baidu
map
Baidu
map
Baidu
map