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Environ Int:儿童哮喘和鼻炎与家庭潮湿相关接触相关性研究

2019-04-04 AlexYang MedSci原创

在2010年和2012年之间,有研究人员对来自中国7个城市的40010名学龄前儿童的家庭环境与健康结果进行了观察性的研究。在研究中,他们调查了当前居住环境的6个潮湿相关的指标(可见的霉菌斑、可见潮湿污渍、潮湿衣物及/或床上用品、水渍、窗玻璃凝结和发霉气味)与早期居住环境的3个潮湿相关指标(可见的霉菌斑、窗玻璃凝结和发霉气味)与儿童哮喘和鼻炎之间的相关性。研究发现,在多水平的逻辑回归分析中,当前居住

在2010年和2012年之间,有研究人员对来自中国7个城市的40010名学龄前儿童的家庭环境与健康结果进行了观察性的研究。

在研究中,他们调查了当前居住环境的6个潮湿相关的指标(可见的霉菌斑、可见潮湿污渍、潮湿衣物及/或床上用品、水渍、窗玻璃凝结和发霉气味)与早期居住环境的3个潮湿相关指标(可见的霉菌斑、窗玻璃凝结和发霉气味)与儿童哮喘和鼻炎之间的相关性。研究发现,在多水平的逻辑回归分析中,当前居住环境的可见的霉菌斑和可见潮湿污渍与医生诊断的哮喘和过敏性鼻炎显著相关(调整后风险比(AORs)范围:1.18-1.35)。所有潮湿相关的指标均与喘息和鼻炎风险的增加显著相关(AORs范围:1.16-2.64)。潮湿指标的积累数量也于所研究疾病增加的风险呈现正相关的剂量响应。喘息和鼻炎的相关性在北方儿童和南方儿童中相似。另外,研究人员在没有过敏家族历史和没有哮喘和过敏性鼻炎的儿童敏感性分析中获得了相似的结果。对2011年中国大陆的3-6岁儿童来说,他们推测有90000(2.02%)名哮喘儿童和59000(1.09%)名过敏性鼻炎儿童的病因归结于当前居住环境中可见霉菌斑的接触。

最后,研究人员指出,他们的结果表明了早期和一直接触家庭潮湿因素是儿童哮喘和鼻炎的风险因子。

原始出处:


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