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J Am Acad Dermatol:指甲病变或能识别银屑病关节炎

2017-07-13 xiaoxiao MedSci原创

银屑病关节炎(PsA)是一种与银屑病相关的炎性关节病,有银屑病皮疹并伴有关节和周围软组织疼痛、肿胀、压痛、僵硬和运动障碍。也被称为牛皮癣性关节炎,是一种血清阴性(即血清类风湿因子阴性)的关节炎,典型地表现为慢性、复发性、良性丘疹鳞屑性的皮肤损害、指(趾)甲损害、慢性、复发性、侵蚀性的多关节炎周围和(或)脊椎关节和以前葡萄膜炎、结膜炎为主要病变的眼部损害。背景:银屑病关节炎(PsA)患者常出现指甲病

银屑病关节炎(PsA)是一种与银屑病相关的炎性关节病,有银屑病皮疹并伴有关节和周围软组织疼痛、肿胀、压痛、僵硬和运动障碍。也被称为牛皮癣性关节炎,是一种血清阴性(即血清类风湿因子阴性)的关节炎,典型地表现为慢性、复发性、良性丘疹鳞屑性的皮肤损害、指(趾)甲损害、慢性、复发性、侵蚀性的多关节炎周围和(或)脊椎关节和以前葡萄膜炎、结膜炎为主要病变的眼部损害。背景:银屑病关节炎(PsA)患者常出现指甲病变,但对这些病变的具体内容却知之甚少。目的:确定指甲症状是否可以用来鉴别银屑病关节炎和无关节炎的银屑病。方法:研究人员回顾了2003年7月-2015年2月,在日本的东京国际医院就诊的118例PsA和974例无关节炎的银屑病患者的临床资料。根据银屑病关节炎分类标准对PsA患者进行分类。皮损面积的严重程度用银屑病皮损面积和严重程度指数进行评估,并对9种指甲类型进行了调查。结果:PsA患者指甲受累的发生率约为67.6%。女性、存在横向凹槽、指甲剥离以及甲下裂片形出血都与PsA显著相关,与指甲存在横向凹槽的相关性最强(比值比,5.01;95%置信区间,2.31-10.8;P <0.01)。此外,

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    2018-04-29 lishizhe
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    2018-05-24 ycmayy
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    2017-07-23 laoli

    学习了,谢谢分享!

    0

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    2017-07-16 虈亣靌

    谢谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1651859, encodeId=818a16518591b, content=<a href='/topic/show?id=3a3e1e9504' target=_blank style='color:#2F92EE;'>#ACA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1795, encryptionId=3a3e1e9504, topicName=ACA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=843c24278901, createdName=lishizhe, createdTime=Sun Apr 29 14:56:00 CST 2018, time=2018-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678403, encodeId=329016e840317, content=<a href='/topic/show?id=a6f85642ebd' target=_blank style='color:#2F92EE;'>#指甲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56427, encryptionId=a6f85642ebd, topicName=指甲)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3ee927698160, createdName=ycmayy, createdTime=Thu May 24 19:56:00 CST 2018, time=2018-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225319, encodeId=72b622531959, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Sun Jul 23 08:30:15 CST 2017, time=2017-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222972, encodeId=f03a2229e253, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Jul 16 19:51:20 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222822, encodeId=a2e6222822a2, content=非常感谢,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/7gcDIibiafYAAXSicO2lQH9E54CZv1GXQ7mreyOcYAr602zBBR427zZNvyiamoNRwDblRdeGb4lz8QvGYxGarrkyOw/132, createdBy=bba82068573, createdName=松鼠上树, createdTime=Sun Jul 16 08:33:58 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265469, encodeId=bdfd126546938, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Jul 15 10:56:00 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222096, encodeId=15cf222096a5, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Fri Jul 14 07:18:06 CST 2017, time=2017-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222041, encodeId=1e6a22204148, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Fri Jul 14 06:45:30 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-16 松鼠上树

    非常感谢,学习了

    0

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    2017-07-15 lmm397
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    2017-07-14 lou.minghong

    学习了谢谢分享

    0

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    2017-07-14 130****4638

    学习了谢谢分享

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