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JAMA Inter Med:禁食和每日热量限制,哪个减肥更有效?

2017-05-02 MedSci MedSci原创

伊利诺伊州芝加哥大学运动学系的营养学专家John F Trepanowski博士5月1日在JAMA内科在线发表的文章中报道。

伊利诺伊州芝加哥大学运动学系的营养学专家John F Trepanowski博士5月1日在JAMA内科在线发表的文章中报道。

在100名肥胖成人的随机试验中,6个月12个月时的体重减轻与替代禁食方案或减少热量摄入的方案相比,体重减轻的维持因素和心血管危险标志物相似。这两个干预组中的人在12个月时比无干预对照组的体重减少了5%。然而,禁食隔夜组(38%)的辍学率高于受限制热量组(29%)或对照组(26%)。

研究人员在10年前开始研究间歇性禁食对体重减轻的影响,并从几项临床试验中公布了数据。2011年,另一组研究人员将107名绝经前妇女纳入随机对照试验,比较间歇性禁食(每周2天)或连续卡路里限制6个月,并报告了两组相似的体重减轻和改善的心血管危险标志物。在2011年至2015年的研究中,Varady博士及其同事招收了14名男性和86名18至65岁的女性(平均年龄44岁,体重指数(BMI)25至39.9(平均BMI,35))。参与者习惯久坐,无心血管疾病或糖尿病。他们被随机分配到隔日禁食,卡路里限制或对照组,并告知他(她)们不要改变他们的身体活动习惯。指导对照组成员需保持同样的体重,不提供该组成员任何营养指导,但如果完成了研究,他们被承诺获得1年的营养咨询和健身会员资格。在减肥阶段,禁食期间的参加者被指示在空腹时一餐(午餐)消耗其基线卡路里(约500卡路里)的25%,在三餐之间的时间消耗其平均热量分解的125%。间歇模式重复6个月。受限制的热量组中的人被指示每天摄入热量减少25%,持续6个月。

前三个月,两个干预组的参与者接收每周食物供应(精益烹饪加水果,蔬菜和其他食物)。在维护阶段,每日热量限制组的人们恢复了基线吃的100%的卡路里,而另一组干预组中的热量则被指示在替代品中摄取基线卡路里的50%和150%天。6个月时,干预组的参与者比对照组减少了6.8%。 12个月,替代禁食组和限制性热量组的参与者分别比对照组的参与者分别减少6%和5.3%。6个月至12个月两组间干预组平均血压,心率,甘油三酯,空腹血糖,空腹胰岛素,胰岛素抵抗,C-反应蛋白或高半胱氨酸差异无统计学意义。但是,隔夜禁食组的许多参与者每隔一天难以坚持500卡路里,随着试验的进行,将他们的饮食改为“事实上”每日热量限制饮食,其他人简单地退出研究。

这些研究结果表明,与日常卡路里限制相比,大多数肥胖个体的替代日禁食长期可能不太可持续。然而,“较小部分的肥胖个体可能更喜欢这种能量限制模式,而不是日常限制。由于许多参与者在研究进入时具有正常的胆固醇水平和血压,所以心血管危险因素对饮食的反应没有改变。该研究组希望对糖尿病前期的肥胖患者进行为期2年的研究,以了解间歇性禁食可能与降低发生糖尿病的风险相关。

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    2017-05-19 lou.minghong

    学习

    0

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    2017-05-17 QFXL123456

    好像健康报见过相关文章,学习了

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=199802, encodeId=f74d199802f4, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Fri May 19 05:42:10 CST 2017, time=2017-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=199263, encodeId=3d94199263c6, content=好像健康报见过相关文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhRvIvBCic3jbz4PVDcMREDl6iaWw7opPo99JEXWc0tmIrGaXGPP0y58DKDiajZfV2qR3qXdCgwIyhVq/0, createdBy=d71a1955931, createdName=QFXL123456, createdTime=Wed May 17 16:04:28 CST 2017, time=2017-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336920, encodeId=38f313369205c, content=<a href='/topic/show?id=91386e25889' target=_blank style='color:#2F92EE;'>#热量限制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67258, encryptionId=91386e25889, topicName=热量限制)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/L2dMhrxjvSWuPWKZZP1I83Rw21EWia7LVTYJibLQkb4oTibrYLwhnAXntTBWR3FruIzKfNMiaBwhYV0AKNmiaNxfialg/132, createdBy=6ea92500119, createdName=ms9608593228839890, createdTime=Wed May 03 23:49:00 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607459, encodeId=b006160e45991, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed May 03 23:49:00 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1613833, encodeId=7213161383370, content=<a href='/topic/show?id=d87e6e25687' target=_blank style='color:#2F92EE;'>#热量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67256, encryptionId=d87e6e25687, topicName=热量)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bba919440409, createdName=ms2536978994064944, createdTime=Wed May 03 23:49:00 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193059, encodeId=ee7319305974, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLEZQLsqPsCbsOnBS1AERT05H5eKZXUPMd8o1fzdcmdLAGj7j0Z5ia7qvh5a4ziakicAQkKsFGwmJLA0/0, createdBy=3caa2052896, createdName=137****4081, createdTime=Wed May 03 05:08:51 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193049, encodeId=d837193049b1, content=不错哦,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83epr1MZHfgreGEFrpiapjCGIQGZhkpjicialc8h7VoU0AjNiaSgpaZjNuIqq1KVbmI19JwrN2sdwTdWVSw/132, createdBy=f6692009961, createdName=sy3923582, createdTime=Wed May 03 01:17:35 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=199802, encodeId=f74d199802f4, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Fri May 19 05:42:10 CST 2017, time=2017-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=199263, encodeId=3d94199263c6, content=好像健康报见过相关文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhRvIvBCic3jbz4PVDcMREDl6iaWw7opPo99JEXWc0tmIrGaXGPP0y58DKDiajZfV2qR3qXdCgwIyhVq/0, createdBy=d71a1955931, createdName=QFXL123456, createdTime=Wed May 17 16:04:28 CST 2017, time=2017-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336920, encodeId=38f313369205c, content=<a href='/topic/show?id=91386e25889' target=_blank style='color:#2F92EE;'>#热量限制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67258, encryptionId=91386e25889, topicName=热量限制)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/L2dMhrxjvSWuPWKZZP1I83Rw21EWia7LVTYJibLQkb4oTibrYLwhnAXntTBWR3FruIzKfNMiaBwhYV0AKNmiaNxfialg/132, createdBy=6ea92500119, createdName=ms9608593228839890, createdTime=Wed May 03 23:49:00 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607459, encodeId=b006160e45991, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed May 03 23:49:00 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1613833, encodeId=7213161383370, content=<a href='/topic/show?id=d87e6e25687' target=_blank style='color:#2F92EE;'>#热量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67256, encryptionId=d87e6e25687, topicName=热量)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bba919440409, createdName=ms2536978994064944, createdTime=Wed May 03 23:49:00 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193059, encodeId=ee7319305974, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLEZQLsqPsCbsOnBS1AERT05H5eKZXUPMd8o1fzdcmdLAGj7j0Z5ia7qvh5a4ziakicAQkKsFGwmJLA0/0, createdBy=3caa2052896, createdName=137****4081, createdTime=Wed May 03 05:08:51 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193049, encodeId=d837193049b1, content=不错哦,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83epr1MZHfgreGEFrpiapjCGIQGZhkpjicialc8h7VoU0AjNiaSgpaZjNuIqq1KVbmI19JwrN2sdwTdWVSw/132, createdBy=f6692009961, createdName=sy3923582, createdTime=Wed May 03 01:17:35 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-03 137****4081

    0

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    2017-05-03 sy3923582

    不错哦,学习了

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