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Lancet Dia & Endo：中国早发2型糖尿病患者非致命性心血管疾病的危险性增加

2015-12-16 MedSci MedSci原创

中国早发2型糖尿病非致命性心血管疾病
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2型糖尿病的发病年龄正在逐渐降低。由于非中国早发2型糖尿病患者（这里定义的诊断在<40岁）增加了血管并发症的风险，研究人员调查了在中国早发性 vs 晚发性2型糖尿病对非致命性心血管疾病的影响。研究人员使用了来自中国国家糖化血红蛋白监测系统（CNHSS）的调查数据，其中包括222773例中国2型糖尿病患者，他们在2012年来自于中国的30个省106个城市的630家医院。研究人员记录了人口统计信

2型糖尿病的发病年龄正在逐渐降低。由于非中国早发2型糖尿病患者（这里定义的诊断在<40岁）增加了血管并发症的风险，研究人员调查了在中国早发性 vs 晚发性2型糖尿病对非致命性心血管疾病的影响。研究人员使用了来自中国国家糖化血红蛋白监测系统（CNHSS）的调查数据，其中包括222773例中国2型糖尿病患者，他们在2012年来自于中国的30个省106个城市的630家医院。研究人员记录了人口统计信息和临床概况。非致死性心血管疾病被定义是非致命性的冠状动脉心脏疾病或非致死性中风。非致死性心血管疾病的患病率对中国在2011年人口进行了标准化。研究人员做了Logistic回归分析，得到早发性与晚发性2型糖尿病患者心血管疾病的风险的比值比（OR）。由于CNHSS不包含饮食或生活习惯单独治疗的患者，因此并没有捕捉到关于吸烟或脂质或抗高血压治疗的信息，研究人员从横截面，多中心2型糖尿病患者观察研究（3B研究）验证了研究结果，以确认排除那些仅饮食治疗和没有调整降脂和降压药的患者，在主要分析中没有引入重大偏差。222773例患者招募自2012年4月1日至2012年6月30日，24316（11％）例患者

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08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], 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    2016-11-19 ms9608593228839890

    #DIA#

    0

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    2015-12-27 ms7258648636991762

    #早发#

    0

  3. 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    2016-01-13 howi

    #Lancet#

    0

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encodeId=652f1e7500163, content=<a href='/topic/show?id=3b0959284b9' target=_blank style='color:#2F92EE;'>#早发2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59284, encryptionId=3b0959284b9, topicName=早发2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=767638737607, createdName=nymo, createdTime=Thu Feb 25 00:55:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383199, encodeId=a45b138319911, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2016-01-09 medsic

    不错…

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1637233, encodeId=3c94163e233c2, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Nov 19 19:55:00 CST 2016, time=2016-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664016, encodeId=159d16640163a, content=<a href='/topic/show?id=a20c59283e5' target=_blank style='color:#2F92EE;'>#早发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59283, encryptionId=a20c59283e5, topicName=早发)], attachment=null, authenticateStatus=null, createdAvatar=null, 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encodeId=652f1e7500163, content=<a href='/topic/show?id=3b0959284b9' target=_blank style='color:#2F92EE;'>#早发2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59284, encryptionId=3b0959284b9, topicName=早发2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=767638737607, createdName=nymo, createdTime=Thu Feb 25 00:55:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383199, encodeId=a45b138319911, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2016-01-09 medsic

    哦

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1637233, encodeId=3c94163e233c2, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Nov 19 19:55:00 CST 2016, time=2016-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664016, encodeId=159d16640163a, content=<a href='/topic/show?id=a20c59283e5' target=_blank style='color:#2F92EE;'>#早发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59283, encryptionId=a20c59283e5, topicName=早发)], attachment=null, authenticateStatus=null, createdAvatar=null, 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encodeId=652f1e7500163, content=<a href='/topic/show?id=3b0959284b9' target=_blank style='color:#2F92EE;'>#早发2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59284, encryptionId=3b0959284b9, topicName=早发2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=767638737607, createdName=nymo, createdTime=Thu Feb 25 00:55:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383199, encodeId=a45b138319911, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2016-01-09 medsic

    涨知识！

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1637233, encodeId=3c94163e233c2, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Nov 19 19:55:00 CST 2016, time=2016-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1664016, encodeId=159d16640163a, content=<a href='/topic/show?id=a20c59283e5' target=_blank style='color:#2F92EE;'>#早发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59283, encryptionId=a20c59283e5, topicName=早发)], attachment=null, authenticateStatus=null, createdAvatar=null, 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encodeId=652f1e7500163, content=<a href='/topic/show?id=3b0959284b9' target=_blank style='color:#2F92EE;'>#早发2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59284, encryptionId=3b0959284b9, topicName=早发2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=767638737607, createdName=nymo, createdTime=Thu Feb 25 00:55:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383199, encodeId=a45b138319911, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2016-02-25 nymo

    #早发2型糖尿病#

    0

  8. 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encodeId=652f1e7500163, content=<a href='/topic/show?id=3b0959284b9' target=_blank style='color:#2F92EE;'>#早发2型糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59284, encryptionId=3b0959284b9, topicName=早发2型糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=767638737607, createdName=nymo, createdTime=Thu Feb 25 00:55:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383199, encodeId=a45b138319911, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2015-12-18 aids213

    #2型糖尿病患者#

    0

  9. 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08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2015-12-18 xue8604

    #糖尿病患者#

    0

  10. 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08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473935, encodeId=ed3114e3935ec, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497940, encodeId=10fc149e94019, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 18 08:55:00 CST 2015, time=2015-12-18, status=1, ipAttribution=)]
    2015-12-18 andy2090

    #血管疾病#

    0

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