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Chest：结节病患者可能发生左心室心肌功能改变

2015-11-12 徐媛 MedSci原创

左心室心肌功能
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尽管在已有的报道中结节病患者心肌功能出现改变占20 - 27%,但只有5%的患者有临床症状。本研究评估处于结节病的早期阶段(I期和II期)的患者是否发生左心室心肌功能改变。 该研究共纳入并随访了72名结节病患者（其中53名女性，19名男性，平均年龄为49.1 ± 10.3岁）和作为对照的19名年龄、性别匹配的健康人(14名女性，5名男性，平均年龄48.7 ± 6.5)。所有参与者均进行心脏二维及

尽管在已有的报道中结节病患者心肌功能出现改变占20 - 27%,但只有5%的患者有临床症状。本研究评估处于结节病的早期阶段(I期和II期)的患者是否发生左心室心肌功能改变。

该研究共纳入并随访了72名结节病患者（其中53名女性，19名男性，平均年龄为49.1 ± 10.3岁）和作为对照的19名年龄、性别匹配的健康人(14名女性，5名男性，平均年龄48.7 ± 6.5)。所有参与者均进行心脏二维及彩色多普勒超声检查。利用多普勒超声参数计算右心室、左心室心肌工作指数。

研究结果显示结节病患者二尖瓣A波的峰值流速较E波的峰值流速增高，E/A比值降低，结节病患者射血时间缩短(p< 0.05)。三尖瓣A波峰值流速升高，E波减速时间延长，E/A比值降低(p< 0.05)。然而结节病患者左心室Tei指数较对照组增高(p= 0.021)，而右心室Tei指数与对照组相似(p>0.05)。

左心室心肌功能改变可影响结节病的早期阶段。

原始出处

Aysel Kederli, MD; Sumeyye Gullulu, MD; Funda Coskun, MD; Dilber Yilmaz, MD; Esra Uzaslan, MD.Changes in Myocardial Performance in Sarcoidosis Patients.Chest.2015

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    2016-09-05 doctorJiangchao

    继续学习

    0

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    2016-09-05 doctorJiangchao

    继续关注

    0

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    2016-04-10 xiangyuzhou971

    #EST#

    0

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    2016-01-19 Smile2680

    #Chest#

    0

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    2015-11-14 wushaoling

    #左心室#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=111876, encodeId=af4d1118e648, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Mon Sep 05 23:18:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=111877, encodeId=6c2b1118e72c, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Mon Sep 05 23:18:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050518, encodeId=b9962050518f6, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sun Apr 10 23:08:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1929228, encodeId=0a831929228a9, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Tue Jan 19 13:08:00 CST 2016, time=2016-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413165, encodeId=2868141316589, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Sat Nov 14 07:08:00 CST 2015, time=2015-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=43055, encodeId=4264430552a, content=好好?, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151120/IMG564E75D532AAC6642.jpg, createdBy=d12a1648027, createdName=邓思静, createdTime=Thu Nov 12 16:17:00 CST 2015, time=2015-11-12, status=1, ipAttribution=)]
    2015-11-12 邓思静

    好好?

    0

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