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ACC2011:阵发性房颤合并高血压的患者的左心房直径和房颤发生频率

2011-05-07 MedSci原创 MedSci原创

     背景:众所周知,左心房直径(LAD)和房颤的发病率相关。但是,LAD与房颤发生频率的关系仍不得而知。     方法:选取J-RHYTHM II研究中的288名患者,这项随机临床研究的目的是比较CCB和ARB在日本阵发性房颤合并高血压的患者中的治疗效果。LAD的基本结果在心彩超下按标准模式测量得出。在

     背景:众所周知,左心房直径(LAD)和房颤的发病率相关。但是,LAD与房颤发生频率的关系仍不得而知。     方法:选取J-RHYTHM II研究中的288名患者,这项随机临床研究的目的是比较CCB和ARB在日本阵发性房颤合并高血压的患者中的治疗效果。LAD的基本结果在心彩超下按标准模式测量得出。在电话传输心电图下记录28天中房颤发生的频率。采用单变量和多变量线性回归分析评价LAD和房颤发生天数的关系。根据LAD和房颤发生天数将患者分为4组,进行ANOVA比较,并计算95%可信区间(CI)。     结果:LAD与房颤发生的天数相关,LAD每增加10mm,房颤发生天数就增加1.9天(95% CI 0.9-2.8)。在对年龄、性别以及其他可能的混淆因素进行调整后,这一关系仍然成立。平均房颤发生天数与LAD四分位数成线性增长的关系。     结论:在阵发性房颤合并高血压的患者中,LAD与房颤发生天数增加

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    2011-05-09 sodoo

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