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Clin Infect Dis:小小一个口罩,能显著降低移植患者感染率

2016-08-15 Seven L 译 MedSci原创

在杜克大学医学中心接受造血干细胞移植的患者中,一个通用的外科口罩政策导致了呼吸道病毒感染的显著减少。 根据杜克大学医学部的Anthony D. Sung博士,呼吸道病毒感染(RVIS)影响了约30%的造血干细胞移植(HSCT)患者,并且可导致潜在的致命性下呼吸道感染。Sung和他的同事们制定了一个政策:要求所有直接接触HSCT患者的医务人员、照顾者、拜访人员、病人等,在患者3英尺范围内戴口罩;不论

在杜克大学医学中心接受造血干细胞移植的患者中,一个通用的外科口罩政策导致了呼吸道病毒感染的显著减少。

根据杜克大学医学部的Anthony D. Sung博士,呼吸道病毒感染(RVIS)影响了约30%的造血干细胞移植(HSCT)患者,并且可导致潜在的致命性下呼吸道感染。

Sung和他的同事们制定了一个政策:要求所有直接接触HSCT患者的医务人员、照顾者、拜访人员、病人等,在患者3英尺范围内戴口罩;不论季节或患者是否有症状。该政策于2009年12月开始执行,研究数据来自于2010年1月12日到2014年1月11日;与2003年12月1日到2009年11月30日接受造血干细胞移植的患者数据进行了比较。

戴口罩组(n = 911)RVI总发生率为4.4%;对照组(n = 920)RVI总发生率为10.3%;发生率下降方面的主要病毒为副流感病毒3型(PIV3),从8.3%下降到2.2%。

Sung和他的同事们还观察到同种异体和自体移植患者RVIs的显著下降,数据分别为16.9%到8.3%和5.7%到2.6%。

在戴口罩组相同时间内,没有戴口罩的血液系统肿瘤患者,与对照组相比,RVIs没有下降。

研究者总结说:使用外科口罩可显著减少接受造血干细胞移植的患者的呼吸道病毒感染风险,尤其是PIV3感染;通用的手术口罩的使用可能是骨髓移植单位减少感染的一个强有力的辅助措施。

原始出处:


[1] Surgical mask policy reduces respiratory viral infections in HSCT patients. Healio.2016 August 15.

[2] Sung AD, et al. Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial. Clin Infect Dis. 2016:doi:10.1093/cid/ciw451.



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  2. [GetPortalCommentsPageByObjectIdResponse(id=2012119, encodeId=19dd2012119fa, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Mon Aug 29 21:25:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146786, encodeId=cec4146e860e, content=感染的预防很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Wed Oct 12 13:20:56 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=135733, encodeId=4be1135e3362, content=虽然没有统计过,但觉得戴口罩肯定对免疫力低下的病人开始非常必要, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Tue Sep 27 09:25:05 CST 2016, time=2016-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108686, encodeId=d7c0108686cf, content=学习一下,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Thu Sep 01 07:28:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106187, encodeId=377910618ea0, content=这篇资讯带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Aug 28 10:23:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307800, encodeId=0cb4130e80080, content=<a href='/topic/show?id=2be638263f4' target=_blank style='color:#2F92EE;'>#口罩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38263, encryptionId=2be638263f4, topicName=口罩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Wed Aug 17 13:25:00 CST 2016, time=2016-08-17, status=1, ipAttribution=)]
    2016-10-12 童小孩

    感染的预防很重要

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2012119, encodeId=19dd2012119fa, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Mon Aug 29 21:25:00 CST 2016, time=2016-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146786, encodeId=cec4146e860e, content=感染的预防很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Wed Oct 12 13:20:56 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=135733, encodeId=4be1135e3362, content=虽然没有统计过,但觉得戴口罩肯定对免疫力低下的病人开始非常必要, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Tue Sep 27 09:25:05 CST 2016, time=2016-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108686, encodeId=d7c0108686cf, content=学习一下,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Thu Sep 01 07:28:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106187, encodeId=377910618ea0, content=这篇资讯带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Aug 28 10:23:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307800, encodeId=0cb4130e80080, content=<a href='/topic/show?id=2be638263f4' target=_blank style='color:#2F92EE;'>#口罩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38263, encryptionId=2be638263f4, topicName=口罩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Wed Aug 17 13:25:00 CST 2016, time=2016-08-17, status=1, ipAttribution=)]
    2016-09-27 童小孩

    虽然没有统计过,但觉得戴口罩肯定对免疫力低下的病人开始非常必要

    0

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    2016-09-01 1771ae4158m

    学习一下,好

    0

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    2016-08-28 李东泽

    这篇资讯带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。

    0

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