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JCEM:超过50年的1型糖尿病血糖控制获益几何?

2017-08-02 xuyihan MedSci原创

之前的研究表明50年或以上的1型糖尿病患者(Medalists),其血糖控制水平与糖尿病并发症无关,除了心血管疾病(CVD),这与之前注册研究的记录相反。

之前的研究表明50年或以上的1型糖尿病患者(Medalists),其血糖控制水平与糖尿病并发症无关,除了心血管疾病(CVD),这与之前注册研究的记录相反。

为了进一步验证这些初步的研究结果并确定大队列层面上个人死亡的因素,Liane J. Tinsley等进行了横断面和纵向设计的研究。该研究纳入50年的Medalists患者,检测糖尿病血管和大血管的并发症及死亡率。

研究结果显示在Medalist患者中血糖控制与小血管并发症并不相关,在整个队列中与CVD显着相关。CVD是最大的致死病因,而糖化血红蛋白并不是死亡的独立预后因素。除此之外,运动锻炼减轻由CVD所致死亡风险。

几乎没有长病程的1型糖尿病大群体来检测长期暴露于高血糖的影响。该研究结果表明,血糖控制、并发症和死亡率在1型糖尿病老年患者中可能会有所改变。同时也表明仔细血糖控制在1型糖尿病老年患者中的必要性。

原始出处:


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    2017-10-10 smallant2015
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    2018-01-04 achengzhao
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    2017-08-03 184****9840

    学习了谢谢分享

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