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难治性高血压患者易并存睡眠呼吸暂停

2016-08-10 许菁 中国循环杂志

研究发现,难治性高血压患者较一般高血压患者更易发生睡眠呼吸暂停综合征,由此这类患者的缺血事件与心衰风险也会增加。 本研究中的470 386例高血压患者中,有7.2%患者存在睡眠呼吸暂停综合征,9.6%患者为难治性高血压。 研究者发现,相比于非难治性高血压患者,难治性高血压患者的睡眠呼吸暂停综合征发生风险增加16%。 此外,肥胖(BMI≥30kg/m2)高血压患者的睡眠

研究发现,难治性高血压患者较一般高血压患者更易发生睡眠呼吸暂停综合征,由此这类患者的缺血事件与心衰风险也会增加。

 

本研究中的470 386例高血压患者中,有7.2%患者存在睡眠呼吸暂停综合征,9.6%患者为难治性高血压。

 

研究者发现,相比于非难治性高血压患者,难治性高血压患者的睡眠呼吸暂停综合征发生风险增加16%

 

此外,肥胖(BMI≥30kg/m2)高血压患者的睡眠呼吸暂停综合征发生风险增加2.6倍,男性患者的睡眠呼吸暂停风险增加1.2倍。

 

早有研究显示,睡眠呼吸暂停综合征与高血压之间存在双向相关性。阻塞性睡眠呼吸暂停综合征可通过交感神经兴奋增强、内皮功能损伤、肾素-血管紧张素-醛固酮系统紊乱等机制引起血压增高。

 

该研究还发现,合并睡眠呼吸暂停综合征的难治性高血压的患者发生缺血性心脏事件风险增加24%,充血性心衰发生风险增加43%

 

因此研究者表示,对于难治性高血压患者,应注意有无睡眠呼吸暂停综合征,并及时给予相应治疗。

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    2016-08-12 freve
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    2016-08-10 1dd8c52fm63(暂无匿称)

    学习学习!

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