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纪念张丽珠教授诞辰97周年 乔杰院士领衔北医三院义诊

2018-01-16 朱旭清 健康界

<!--ewebeditor:page title=""--> <div>回望中国医学历程,这一笔注定浓墨重彩:1988年3月10日,67岁的张丽珠教授成为中国大陆首例试管婴儿缔造者。这背后的一个重要原因是,她收到多个不孕症家庭载满心酸与希冀的6000多封来信。</div><div><br></div><div>2018年1月15日,张丽珠教授诞辰97周年纪念日。这一年,是中国大陆辅助生殖技术成功应用30周年,是北京大学第三医院(下称北医三院)建院60周年。正因为如此,中国工程院院士、北医三院院长乔杰率领生殖医学中心缅怀张丽珠教授,开展义诊活动,传承大爱。</div><div><br></div><div>这,也是北医三院院庆年系列学术活动的首场活动。</div><div><br></div><div style="text-align: center;"><img src="https://img.medsci.cn/webeditor/uploadfile/201801/20180116200806524.png" border="0"></div><div><br></di

回望中国医学历程,这一笔注定浓墨重彩:1988年3月10日,67岁的张丽珠教授成为中国大陆首例试管婴儿缔造者。这背后的一个重要原因是,她收到多个不孕症家庭载满心酸与希冀的6000多封来信。

2018年1月15日,张丽珠教授诞辰97周年纪念日。这一年,是中国大陆辅助生殖技术成功应用30周年,是北京大学第三医院(下称北医三院)建院60周年。正因为如此,中国工程院院士、北医三院院长乔杰率领生殖医学中心缅怀张丽珠教授,开展义诊活动,传承大爱。

这,也是北医三院院庆年系列学术活动的首场活动。


踏上医路

1921年,张丽珠出生于上海。参加过辛亥革命的父亲张耀曾认为,“效忠社会则贤女胜过不宵之子,继承血统则女与子又有何区别”;“垦恳尽吾能,不暇问收获,辛辛尽吾时,不知有穷遏”,使得张丽珠从小就形成坚韧不拔、大爱家国的品质。

1937年,为响应“航空救国”号召,张丽珠报考南京中央大学航空工程系。当时恰逢南京失守,学校搬迁,她不得不放弃造飞机、开飞机报效祖国的打算。后来,她读到纪念父亲的一句话——“良医良相尽,此事最堪哀”,于是立志成为一名好医生。自此,张丽珠踏上医学之路。

从1938年就读上海圣约翰大学医学院,到1944年成为上海沪西妇产科医院住院医师,再到1946年、1949年分别留学美国和英国,张丽珠心中始终惦记,“迫切地需要掌握新理论和新的医疗方法,以克服临床的盲目性和一般化”。

1951年,张丽珠学成回归中国大陆。这期间,她一面受到英国多方力量的阻挠,一面受到香港友人的真情挽留,但最终还是想方设法回到中国大陆。当她第一次看到珠江口上空飘扬的五星红旗时潸然泪下,“亲爱的祖国,我回来了”。

造就传奇

回国后不久,张丽珠便被调入北京医学院(现北京大学医学部)第一附属医院,1958年参与第三附属医院(北医三院)的创建。

20世纪60年代,当时北京市海淀区八大学院大批女学生闭经,引起社会和政府重视。张丽珠经过调查和研究,明确发病原因在下丘脑而并非卵巢,是重体力劳动和营养不足导致的营养不良性闭经。这也成为北医三院生殖内分泌专业的开端。

奠定了基础,生殖内分泌科的发展在北医三院便有了苗头。1978年,世界首例试管婴儿出生,震撼全球。随后几年,张丽珠收到6000多封来自不同不孕症家庭的来信。20世纪80年代初,她根据国外生殖技术进展并结合中国国情,决定开展试管婴儿技术。

“当时开展实验非常艰苦,很多药物和器械都没有,张丽珠老师在国外找了很多人帮忙,不少器械也都是用别的来代替。”北医三院生殖医学中心常务副主任刘平回忆,当时她是张丽珠教授的学生、参与了中国大陆首例试管婴儿的实验,她介绍,那个时候她们从开始认识卵泡是什么样子,到逐渐掌握取卵泡技术,再到将配子进行融合,最后将受精卵植入母体子宫,整个过程经历了多次失败和挑战。“试验失败让人很受挫,但张丽珠老师始终没有放弃。”

得益于张丽珠和团队的坚持与努力,中国大陆试管婴儿研究踩出一串深深的足迹:1984年,体外受精成功;1986年,开展试管婴儿技术应用研究;1987年6月24日,张丽珠对一名不孕症的妇女进行体外受精;1988年3月10日,中国大陆第一例试管婴儿在北医三院诞生。

再接再厉

至今迈过60年风雨的北医三院,经过一个甲子的拼搏,已经成为一家集医疗、教学、科研预防保健为一体的高水平现代化综合性三级甲等医院。

特别值得一提的是,该院生殖医学中心延续张丽珠教授的梦想,始终以患者为中心,勇担社会责任,敢于攻坚克难。印证这些话的是一张长长的“成绩单”:2006年国内首例、世界第二例三冻(冻卵、冻精子、冻胚胎)试管婴儿在北医三院诞生;作为科技部“生殖与发育重大专项”首席科学家、教育部***特聘教授、国家自然科学基金创新研究群体“生殖细胞发育”首席专家,乔杰教授带领团队致力于妇产科及生殖健康相关的临床与基础研究;从遗传学、表观遗传学角度探究人类早期胚胎发育机制,将基础研究成果应用于临床上胚胎植入前遗传学诊断;揭示疑难不孕症发病机制,优化辅助生殖技术方法,提高疑难不孕患者治疗成功率。

另外,北医三院与北京大学合作研究的成果,分别入选科技部2014、2015年度“中国科学十大进展”,团队获批“国家妇产疾病临床医学研究中心”“教育部重点实验室”;2017年,乔杰教授当选中国工程院院士;由乔杰院士作为第一完成人,北京大学第三医院和北京大学共同完成的“配子胚胎发育研究与生育力改善新方法的应用”,荣获2017年度国家科学技术进步奖二等奖。

事实表明,北医三院生殖医学中心的辅助生殖技术,一直结合患者需求,适应社会发展与中国国情,饱受赞誉,备受信赖。二孩政策实施后,该中心被寄予更多期望,更显责重如山。

1月15日下午1点,北医三院的乔杰教授、刘平教授、马彩虹教授、李蓉教授等30多位生殖医学专家,在百忙中纷纷聚至由宣教中心改成的临时诊室里,参加此次义诊活动。2个小时的义诊,300余名患者获得咨询或预约就诊服务,不仅彰显了北医三院关爱患者的情愫,也是传承张丽珠教授大爱无垠医者情怀的生动注解。

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    2018-11-08 snowpeakxu
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    2018-01-18 李东泽

    是很好的学习材料.不错.以后会多学习.

    0

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    2018-01-17 15121100f4m

    向老前辈致敬!

    0

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