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Diabetologia:心脏代谢危险因素与2型糖尿病诊断年龄相关的短期进展

2018-04-10 MedSci MedSci原创

近日,国际杂志 《Diabetologia》上在线发表一项关于来自瑞典国家糖尿病登记处的100,606人的纵向观察的研究,研究心脏代谢危险因素与2型糖尿病诊断年龄相关的短期进展。 相对于迟发型疾病,对早发型2型糖尿病的过早死亡和与之相关的原因尚不清楚。研究人员评估了2型糖尿病诊断的临床特征以及诊断后最初几年与诊断年龄相关的心脏代谢危险因素的关系。 研究队列由2002年至2012年在瑞典

近日,国际杂志 《Diabetologia》上在线发表一项关于来自瑞典国家糖尿病登记处的100,606人的纵向观察的研究,研究心脏代谢危险因素与2型糖尿病诊断年龄相关的短期进展。 相对于迟发型疾病,对早发型2型糖尿病的过早死亡和与之相关的原因尚不清楚。研究人员评估了2型糖尿病诊断的临床特征以及诊断后最初几年与诊断年龄相关的心脏代谢危险因素的关系。 研究队列由2002年至2012年在瑞典国家糖尿病登记中登记的100,606名新诊断的2型糖尿病患者组成,平均随访时间为2.8年。使用连续危险因素的线性混合效应模型和具有二分风险因子的逻辑关联函数的混合广义线性模型进行分析。 研究发现,诊断时年龄最小(18-44岁)的个体在男性中更常见,与所有其他组相比(诊断时年龄45-59岁,60-74岁和≥75岁; p <0.05),在诊断时和在随访期间,体重指数最高(平均33.4 kg/m2),比年龄最大的组高5kg/m 2。尽管所有年龄组的HbA 1c模式相似,但诊断后8年两组之间差异约为5 mmol/mol(0.45%)(p <0.05)。此外,相对于诊断年龄最大的组,诊断年龄较年轻的个体

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    2018-04-10 戒馋,懒,贪

    谢谢分享学习了

    0

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由此可见,该研究结果支持将收缩压的治疗目标值设为140mmHg,并且怀疑无并发症的2型糖尿病患者更低的收缩压目标值(<120或130mmHg)CVD风险会降低。还需要一个随机对照试验来证实这些发现。

营养不良可能是造成2型糖尿病的重要原因

犹他州西南部的研究人员报告说,居住在美国等发达国家的南亚人对营养不良的饮食选择是导致2型糖尿病发病率上升的主要原因。

Diabetes Care:恩格列净如何降低2型糖尿病患者心血管死亡风险?

美国、加拿大、德国和意大利科学家在《Diabetes Care》发表了ENPA-REGOUTCOME试验的中介分析的观点:恩格列净如何降低心血管(CV)死亡风险?

BMJ:2型糖尿病患者服用二肽基肽酶4抑制剂与炎症性肠病发病率相关

在这首个基于人群的研究中,二肽基肽酶4抑制剂的使用与炎性肠道疾病的风险增加有关。尽管这些发现需要被重复,但是医生们应该意识到这种可能的关联。

NEJM:童年到成年早期超重的变化与2型糖尿病风险!

由此可见,7岁时儿童超重与成人2型糖尿病风险增加有关。

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