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Neurology:急性脑卒中后直接肠内与鼻胃管置入患者的预后比较!

2018-01-26 xing.T MedSci原创

由此可见,急性卒中后接受DET的患者与单纯NGT患者相比,出院时残疾更为严重,并伴有较高的住院率、医疗并发症和长期死亡率。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,该研究旨在比较接受直接肠内管与鼻胃管处理的急性卒中患者并发症、残疾和长期死亡率。

在2003年7月1日至2013年3月31日期间,研究人员使用安大略卒中登记中心确定了急性缺血性卒中或脑出血后住院期间单独接受直接肠内置管(DET,胃造口术或空肠造口)或临时鼻胃管(NGT)的患者。研究人员使用倾向性匹配比较了组间出院和评估出院残疾、并发症和死亡率,随访超过2年,并用累计发生率函数来解释相互竞争的风险。

在放置DET的1448例存活至出院的患者中,有1421例成功匹配NGT的患者。 DET患者出院后30天内死亡风险降低(9.7% vs. 15.3%;风险比[HR]为0.61,95%可信区间[CI]为0.49-0.75),但这种差异在对住院时间和出院残疾匹配后被消除(HR为0.90,95%CI为0.70-1.17)。DET患者出院时严重残疾(改良的Rankin量表评分4-5; 89.6% vs. 78.4%)、长期护理(38.0% vs. 16.1%)、吸入性肺炎(14.4% vs. 5.1%)和其他并发症以及2年死亡率(41.1% vs. 35.9%)发生率较高。

由此可见,急性卒中后接受DET的患者与单纯NGT患者相比,出院时残疾更为严重,并伴有较高的住院率、医疗并发症和长期死亡率。

原始出处:

Raed A. Joundi, et al.Outcomes among patients with direct enteral vs nasogastric tube placement after acute stroke.Neurology.2018. https://doi.org/10.1212/WNL.0000000000004962

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    2018-11-18 yinhl1978
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    2018-02-08 方舒

    学习

    0

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    2018-02-01 jyzxjiangqin

    急性脑卒中的治疗.

    0

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科学的多模态影像学检查,包括CTA和CTP,能够提过颅内血管和颅脑灌注情况并能够区分梗死核心和半暗带,从而对静脉溶栓患者的选择提供了可靠科学的信息。本研究提出假说:多模态影像学技术能够增加静脉溶栓的数量并改善治疗预后,并将实验结果发表在Int J Stroke上。

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