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iabetologia:2型糖尿病诊断年龄与血糖控制呈负相关

2013-09-06 佚名 丁香园

为了验证年龄小于65岁时诊断2型糖尿病是否与随后的血糖控制欠佳有关,来自美国麻省总医院Seth A Berkowitz教授及其团队进行了一项研究,该研究发现2型糖尿病诊断年龄较小与随后血糖控制欠佳显著相关。

为了验证年龄小于65岁时诊断2型糖尿病是否与随后的血糖控制欠佳有关,来自美国麻省总医院Seth A Berkowitz教授及其团队进行了一项研究,该研究发现2型糖尿病诊断年龄较小与随后血糖控制欠佳显著相关。该研究结果在线发表在2013年9月1日的《Diabetologia》 杂志上。【原文下载】

该研究中,对来自2005–2010年国家健康与营养调查的数据进行横断面分析。自诉糖尿病的成年人,按糖尿病诊断年龄分为年轻组(<65岁)或年长组(≥65岁)。关注的主要结局是HbA1c>9%(75mmol/mol),次要结局是HbA1c>8%(64mmol/mol)和HbA1c>7%(53mmol/mol)。使用多元logistic回归进行分析。

该研究结果表明,在1438例成年糖尿病患者中,糖尿病诊断年龄<65岁与糖尿病诊断年龄≥65岁相比,有更高比例的患者HbA1c>9%.校正性别、种族、受教育程度、收入、保险、平时护理来源、高血糖药物治疗、糖尿病病程、家族史、BMI和腰围后,糖尿病诊断年龄<65岁与HbA1c>9%、HbA1c>8%、HbA1c>7%几率更高显著相关。年轻组报道较少的并发症,但报告的健康状况较差。

该研究发现,2型糖尿病诊断年龄较小与随后血糖控制欠佳显著相关。

原文下载

Berkowitz SA, Meigs JB, Wexler DJ.Age at type 2 diabetes onset and glycaemic control: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2010.Diabetologia. 2013 Sep 1.

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