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王继光:每2个老人中就有1人患高血压,老年高血压理想用24小时动态血压评估

2017-12-01 朱柳媛 中国循环杂志

如果以60 岁作为老年的界限值,根据诊室收缩压≥140 mmHg或舒张压≥90 mmHg,或服用降压药物进行降压治疗,老年人群高血压的患病率约为50%,即每2 名老年人中就有1 人患有高血压。

随着全球范围内人口的普遍老龄化,老年高血压已成为老年期主要疾病负担。

如果以60 岁作为老年的界限值,根据诊室收缩压≥140 mmHg或舒张压≥90 mmHg,或服用降压药物进行降压治疗,老年人群高血压的患病率约为50%,即每2 名老年人中就有1 人患有高血压。
 
那么,老年高血压该如何诊断和治疗?
 
近期,上海交通大学医学院附属瑞金医院王继光教授在本刊撰文指出,由于老年高血压有其独特的病理生理学与临床特点,诊断和评估需要更加强化的血压监测,最好能够进行24 小时动态血压监测。
 
如果24 小时平均收缩压≥ 130mmHg 或舒张压≥ 80 mmHg;或者白天平均收缩压≥ 135 mmHg 或舒张压≥ 85 mmHg;或者夜间平均收缩压≥ 120 mmHg 或舒张压≥ 70 mmHg,即可诊断高血压。
 
如果不能耐受或没有条件进行动态血压监测,可以进行系统的家庭血压监测作为替代。每天早上起床后、晚上睡觉前各测血压2 次,连续5~7 天,平均收缩压≥135 mmHg 或舒张压≥ 85 mmHg,也可诊断高血压。
 
王继光教授指出,老年高血压危害极大,可导致严重的靶器官损害以及各种心脑血管并发症。积极控制血压,特别是控制到达标水平,可显著降低靶器官损害及各种心脑血管并发症的风险。
 
对大部分老年高血压而言,可将收缩压/舒张压降至140/90mmHg 以下。对于80 岁以上的高龄老年人,适当放宽血压至<150/90 mmHg。
 
我国2010 版高血压指南建议,≥ 65岁老年高血压患者的血压降至150/90mmHg以下,如能耐受,可降至140/90 mmHg。65~80 岁老年人群持续扩大,应考虑在密切监测血压的情况下,将血压降至140/90 mmHg 以下,以充分发挥降压治疗预防心脑血管并发症的作用。
 
中国高血压指南推荐使用5 大类降压药物,即利尿药、钙拮抗剂、血管紧张素转换酶抑制剂、血管紧张素Ⅱ受体拮抗剂及β受体阻滞剂。合并良性前列腺增生的老年高血压患者,可选择α1 受体阻滞剂。
 
在选择药物时,应优先选择使用每日1 次服药可控制24 小时血压的长效药物,不仅降压作用更加平稳,而且有利于提高治疗依从性;如果单药治疗血压不达标,则应进行联合降压治疗;但不论单药,还是联合治疗,如果还没有实现降压达标,都应考虑增加剂量至足剂量。
 
在选择降压药物时,应考虑患者的慢性合并症,如糖尿病代谢综合征、慢性肾脏疾病等,以及靶器官损害或并发症,如蛋白尿、左心室肥厚、冠心病、心力衰竭等。
 
王教授强调,对于收缩压在140~159mmHg 而舒张压<90 mmHg 的1级老年单纯收缩期高血压患者,目前缺乏安慰剂对照的降压治疗临床试验证据,许多临床医生在启动降压治疗时仍有很大疑虑,因此仍需在这一人群中开展深入的临床试验研究。
 
原始出处:王继光. 老年高血压现状与问题.中国循环杂志, 2017,32: 1049-1051.

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    2018-03-05 chengjn
  4. 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    2017-12-04 jihuaijun1112

    学习学习学习

    0

  5. 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  6. 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  7. 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    2017-12-02 thlabcde

    好资料学习了!

    0

  8. 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    2017-12-02 惠映实验室

    不同人的血压类型不同.根据24小时动态血压确定自己血压类型.对于高血压患者.可以很好合理用药.

    0

  9. 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    2017-12-02 zwjnj2

    好好好学习学习学习

    0

  10. 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createdBy=fa9722636957, createdName=1508842480_96220444, createdTime=Sat Dec 02 09:30:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725271, encodeId=7d321e252711c, content=<a href='/topic/show?id=e20b101402' target=_blank style='color:#2F92EE;'>#24小时#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1014, encryptionId=e20b101402, topicName=24小时)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=447433741908, createdName=chengjn, createdTime=Mon Mar 05 15:30:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266595, encodeId=5da12665959f, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Mon Dec 04 01:26:58 CST 2017, time=2017-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478910, encodeId=090114e891098, content=<a href='/topic/show?id=5de08024597' target=_blank style='color:#2F92EE;'>#老年高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80245, encryptionId=5de08024597, topicName=老年高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87307462084, createdName=124985dbm08(暂无昵称), createdTime=Sun Dec 03 14:30:00 CST 2017, time=2017-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1508996, encodeId=148d15089966c, content=<a href='/topic/show?id=a7c83311e88' target=_blank style='color:#2F92EE;'>#动态血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33117, encryptionId=a7c83311e88, topicName=动态血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2c1e10025437, createdName=limedical1977, createdTime=Sun Dec 03 14:30:00 CST 2017, time=2017-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266256, encodeId=836c266256cd, content=好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Dec 02 21:47:24 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266143, encodeId=32b8266143a1, content=不同人的血压类型不同.根据24小时动态血压确定自己血压类型.对于高血压患者.可以很好合理用药., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Dec 02 09:12:07 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266136, encodeId=716f2661360c, content=好好好学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Sat Dec 02 09:03:26 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266129, encodeId=04cc26612980, content=络活喜好像是唯一一个分子长效钙拮抗降压药吧?它的降压效果应该不错吧??, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6opJd8ZxBGSXTuYI9f3JibowIxuPbumDp9e5I5IXQmyzsgicFTPtkPhG828Ms5fCYJddHwsjSu0EPPZJa4lKyglG/0, createdBy=5e931963187, createdName=1e13fec7m04(暂无匿称), createdTime=Sat Dec 02 08:09:49 CST 2017, time=2017-12-02, status=1, ipAttribution=)]
    2017-12-02 1e13fec7m04(暂无匿称)

    络活喜好像是唯一一个分子长效钙拮抗降压药吧?它的降压效果应该不错吧??

    0

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