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Hypertension:如何控制2型糖尿病高血压患者的收缩压?

2017-10-19 MedSci MedSci原创

目前,有主张对糖尿病患者收缩压(SBP)的管理从统一性改为以个体化、以患者为中心,但对于实现治疗目标的SBP水平尚未达成共识。近期,一项发表在杂志Hypertension上的研究旨在评估SBP与心血管疾病(CVD)风险和糖尿病患者的全因死亡率之间的关系,以确定以患者为中心的治疗目标。此项研究对95086名2型糖尿病和高血压成人初级保健患者进行了回顾性研究。使用年度SBP记录(更新的SBP),平均随

目前,有主张对糖尿病患者收缩压(SBP)的管理从统一性改为以个体化、以患者为中心,但对于实现治疗目标的SBP水平尚未达成共识


近期,一项发表在杂志Hypertension上的研究旨在评估SBP与心血管疾病(CVD)风险和糖尿病患者的全因死亡率之间的关系,以确定以患者为中心的治疗目标。

此项研究对95086名2型糖尿病高血压成人初级保健患者进行了回顾性研究。使用年度SBP记录(更新的SBP),平均随访时间为5.9年,使用Cox比例风险回归评估总体CVD、全因死亡率及其与SBP相关的复合体的风险。通过分层患者的基线特征对CVD的发生率进行亚组分析。
 
此项研究结果显示:2型糖尿病患者的CVD和全因死亡风险最低的SBP范围为130〜134 mmHg。在不考虑患者的特征的情况下,SBP与CVD和全因死亡风险之间为J型曲线关系。

此外,所有患有SBP <125 mm Hg或≥140mm Hg的患者,其CVD和死亡风险均升高。无论患者的特征如何,药物治疗中SBP达到125至139 mmHg的水平,这表明在糖尿病管理中,SBP治疗目标<140 mmHg和个体化的SBP靶标可能不是必需的。

原始出处:
Wan EYF, Yu EYT, et al. Do We Need a Patient-Centered Target for Systolic Blood Pressure in Hypertensive Patients With Type 2 Diabetes Mellitus? Hypertension. 2017 Oct 16. pii: HYPERTENSIONAHA.117.10034. doi: 10.1161/HYPERTENSIONAHA.117.10034.

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    2018-04-03 feather89
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    2017-10-20 1391e9f2a7m

    好文章.认真学习了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1840314, encodeId=715318403149a, content=<a href='/topic/show?id=10905e20546' target=_blank style='color:#2F92EE;'>#收缩压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57205, encryptionId=10905e20546, topicName=收缩压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Fri Jun 08 14:59:00 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726811, encodeId=898e1e26811fa, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Apr 03 08:59:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038770, encodeId=118c2038e70f3, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Mon May 07 06:59:00 CST 2018, time=2018-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804328, encodeId=b6d4180432808, content=<a href='/topic/show?id=8c80e6811b2' target=_blank style='color:#2F92EE;'>#糖尿病高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76811, encryptionId=8c80e6811b2, topicName=糖尿病高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c5e117, createdName=lujian, createdTime=Wed Jun 20 17:59:00 CST 2018, time=2018-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448214, encodeId=887614482145c, content=<a href='/topic/show?id=5a9c102681f2' target=_blank style='color:#2F92EE;'>#高血压患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102681, encryptionId=5a9c102681f2, topicName=高血压患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4665409655, createdName=维他命, createdTime=Sat Oct 21 10:59:00 CST 2017, time=2017-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501217, encodeId=0f9b150121e73, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Sat Oct 21 10:59:00 CST 2017, time=2017-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254472, encodeId=d4762544e25d, content=好文章.认真学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo61WAV0ROeLAoicPxPKoKaogwLWLL8STv86qplbdOibN2YR4KxkJicqNectCXGR8gPJhGLc7yYLSdnpx4kaVXndTfu/0, createdBy=a6962042337, createdName=1391e9f2a7m, createdTime=Fri Oct 20 07:09:33 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=254389, encodeId=673a254389d8, content=学习了.谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Oct 19 21:48:36 CST 2017, time=2017-10-19, status=1, ipAttribution=)]
    2017-10-19 changjiu

    学习了.谢谢

    0

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