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Stroke:急性缺血性卒中患者发生心肌梗死的发病率和结局!

2017-10-12 MedSci MedSci原创

目前,关于急性缺血性卒中(AIS)并发急性心肌梗死(AMI)的发病率和患者结局的研究数据十分有限。近期,一项发表在杂志Stroke上的研究使用全国数据库评估了AIS患者的AMI发生率、治疗方式和结局。此项研究确定2003年至2014年间国家住院的AIS患者。评估了AMI发病率及其相关住院死亡率的趋势。使用单变量和多变量逻辑回归评估AMI的预测因子。在AMI患者和无AMI患者的倾向匹配组的比较分析中

目前,关于急性缺血性卒中(AIS)并发急性心肌梗死(AMI)的发病率和患者结局的研究数据十分有限。近期,一项发表在杂志Stroke上的研究使用全国数据库评估了AIS患者的AMI发生率、治疗方式和结局。


此项研究确定2003年至2014年间国家住院的AIS患者。评估了AMI发病率及其相关住院死亡率的趋势。使用单变量和多变量逻辑回归评估AMI的预测因子。在AMI患者和无AMI患者的倾向匹配组的比较分析中评估了AMI对住院结局的影响。

此项研究结果显示:在国家住院患者中共有864 043名AIS患者,其中13 573例(1.6%)患有AMI(79.5%非ST段抬高型心肌梗死和20.5%ST段抬高型心肌梗死梗死)。AMI患者和无AMI患者住院死亡率分别为21.4%和7.1%,P <0.001。

住院时间和护理费用在AMI组高出50%。在多变量逻辑回归分析中,AIS后AMI最强的预测因素是高龄、冠状动脉疾病史、慢性肾功能不全、机械性血栓切除术史以及节律和传导异常。在AMI组,经历冠状动脉造影和经皮冠状动脉介入治疗与较低的院内死亡率密切相关(优势比,0.34 [置信区间,0.23-0.51]和0.26 [置信区间,0.20-0.34],P < 0.001)。然而,这些分别在7.5%和2%的患者中进行。

此项研究结果表明:AMI合并卒中使得住院死亡率和护理成本增加。接受冠状动脉造影或无干预的患者可能改善的生存率。

原始出处:
Alqahtani F, Aljohani S, et al. Incidence and Outcomes of Myocardial Infarction in Patients Admitted With Acute Ischemic Stroke. Stroke. 2017 Oct 10. pii: STROKEAHA.117.018408. doi: 10.1161/STROKEAHA.117.018408.

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    2017-10-12 changjiu

    学习了.谢谢

    0

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