Baidu
map

Circulation:急性风湿热与风湿性心脏病的长期结果

2016-07-21 fsy 译 MedSci原创

近期,来自澳大利亚的研究人员调查了急性风湿热(ARF)和风湿性心脏病(RHD)人群的不良预后,以及合并症和人口因素对这些结果的影响。研究人员统计了澳大利亚北部地区居民的数据(RHD登记,医院,和死亡数据)。在1997年到2013年期间,572名居民被诊断为ARF,1248名居民被诊断为RHD(这些人群中94.9%为原著民),研究人员计算了该人群的ARF复发率,从ARF进展到RHD再到严重RHD的发

近期,来自澳大利亚的研究人员调查了急性风湿热(ARF)和风湿性心脏病(RHD)人群的不良预后,以及合并症和人口因素对这些结果的影响。

研究人员统计了澳大利亚北部地区居民的数据(RHD登记、医院和死亡数据)。在1997年到2013年期间,572名居民被诊断为ARF,1248名居民被诊断为RHD(这些人群中94.9%为原著民),研究人员计算了该人群的ARF复发率,从ARF进展到RHD再到严重RHD的发病率,RHD并发症的发生率(心脏衰竭、心内膜炎、卒中和房颤)和死亡率。

在ARF发病后第一年中,ARF复发率最高(发生率,每100人-年3.7例),但低水平风险持续时间>10年。在第一年中,进展到RHD的发生率也是最高的(发生率,35.9),比ARF复发率高出近10倍。原著民被诊断为RHD时,年龄都较小,特别是男性(17岁)。RHD诊断后的第一年中并发症的发病率也是最高的:心衰发病率为每100人-年9.09例,房颤为4.70,心内膜炎为1.00;,卒中为0.58。原著民RHD患者比非原著民患者死亡率高(危险比,6.55;95%置信区间,2.45-17.51),其中28%可由肾功能衰竭合并症和使用有害酒精来解释。城市居民的RHD并发症和死亡率比偏远地区的居民要高。

本研究为ARF/RHD提供了新的重要的预后信息。在考虑合并症后,原著民RHD患者的生存差异依然持续存在,表明有其他因素会导致死亡,这值得进一步研究。

原始出处:

Vincent Y.F. He, John R. Condon, Anna P. Ralph,et al.Long-Term Outcomes From Acute Rheumatic Fever and Rheumatic Heart Disease,Circulation,2016.7.20

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=135115, encodeId=d5df135115e0, content=文章很好值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 25 17:21:00 CST 2016, time=2016-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723752, encodeId=25831e237525d, content=<a href='/topic/show?id=ac899e0343c' target=_blank style='color:#2F92EE;'>#长期结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97034, encryptionId=ac899e0343c, topicName=长期结果)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee6a33536665, createdName=zhucaizhong7777, createdTime=Sat Dec 24 20:03:00 CST 2016, time=2016-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004157, encodeId=49aa200415e26, content=<a href='/topic/show?id=a50210083332' target=_blank style='color:#2F92EE;'>#风湿热#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100833, encryptionId=a50210083332, topicName=风湿热)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Dec 08 13:03:00 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341051, encodeId=7b331341051e5, content=<a href='/topic/show?id=ae7b100829f2' target=_blank style='color:#2F92EE;'>#风湿性心脏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100829, encryptionId=ae7b100829f2, topicName=风湿性心脏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Sat Jul 23 12:03:00 CST 2016, time=2016-07-23, status=1, ipAttribution=)]
    2016-09-25 1e10c84am36(暂无匿称)

    文章很好值得关注

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=135115, encodeId=d5df135115e0, content=文章很好值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 25 17:21:00 CST 2016, time=2016-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723752, encodeId=25831e237525d, content=<a href='/topic/show?id=ac899e0343c' target=_blank style='color:#2F92EE;'>#长期结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97034, encryptionId=ac899e0343c, topicName=长期结果)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee6a33536665, createdName=zhucaizhong7777, createdTime=Sat Dec 24 20:03:00 CST 2016, time=2016-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004157, encodeId=49aa200415e26, content=<a href='/topic/show?id=a50210083332' target=_blank style='color:#2F92EE;'>#风湿热#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100833, encryptionId=a50210083332, topicName=风湿热)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Dec 08 13:03:00 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341051, encodeId=7b331341051e5, content=<a href='/topic/show?id=ae7b100829f2' target=_blank style='color:#2F92EE;'>#风湿性心脏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100829, encryptionId=ae7b100829f2, topicName=风湿性心脏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Sat Jul 23 12:03:00 CST 2016, time=2016-07-23, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=135115, encodeId=d5df135115e0, content=文章很好值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 25 17:21:00 CST 2016, time=2016-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723752, encodeId=25831e237525d, content=<a href='/topic/show?id=ac899e0343c' target=_blank style='color:#2F92EE;'>#长期结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97034, encryptionId=ac899e0343c, topicName=长期结果)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee6a33536665, createdName=zhucaizhong7777, createdTime=Sat Dec 24 20:03:00 CST 2016, time=2016-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004157, encodeId=49aa200415e26, content=<a href='/topic/show?id=a50210083332' target=_blank style='color:#2F92EE;'>#风湿热#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100833, encryptionId=a50210083332, topicName=风湿热)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Dec 08 13:03:00 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341051, encodeId=7b331341051e5, content=<a href='/topic/show?id=ae7b100829f2' target=_blank style='color:#2F92EE;'>#风湿性心脏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100829, encryptionId=ae7b100829f2, topicName=风湿性心脏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Sat Jul 23 12:03:00 CST 2016, time=2016-07-23, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=135115, encodeId=d5df135115e0, content=文章很好值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 25 17:21:00 CST 2016, time=2016-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723752, encodeId=25831e237525d, content=<a href='/topic/show?id=ac899e0343c' target=_blank style='color:#2F92EE;'>#长期结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97034, encryptionId=ac899e0343c, topicName=长期结果)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee6a33536665, createdName=zhucaizhong7777, createdTime=Sat Dec 24 20:03:00 CST 2016, time=2016-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2004157, encodeId=49aa200415e26, content=<a href='/topic/show?id=a50210083332' target=_blank style='color:#2F92EE;'>#风湿热#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100833, encryptionId=a50210083332, topicName=风湿热)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Dec 08 13:03:00 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341051, encodeId=7b331341051e5, content=<a href='/topic/show?id=ae7b100829f2' target=_blank style='color:#2F92EE;'>#风湿性心脏病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100829, encryptionId=ae7b100829f2, topicName=风湿性心脏病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Sat Jul 23 12:03:00 CST 2016, time=2016-07-23, status=1, ipAttribution=)]
Baidu
map
Baidu
map
Baidu
map