LANCET：阿斯利康和辉瑞疫苗混合使用时，发热、寒战和疼痛更常见

2021-05-15 MedSci原创 MedSci原创

阿斯利康和辉瑞疫苗混合使用时，发热、寒战和疼痛更常见

研究人员报告称，与标准剂量方案相比，牛津大学阿斯利康和辉瑞生物科技covid-19疫苗的混合剂量导致更频繁的轻到中度反应。牛津大学领导的Com-COV研究正在调查两种疫苗混合剂量的反应原性和免疫原性。研究成果发表在LANCET杂志。牛津大学儿科和疫苗学副教授、该试验的首席研究员马修·斯内普说:“虽然这是我们试图通过这些研究探索的第二部分，但我们告知人们这些数据是重要的，特别是由于一些国家正在考虑这些混合剂量计划。“这项研究的结果表明，混合剂量计划可能会导致免疫接种后第二天缺勤的情况增加，这是在为医护人员规划免疫接种时需要考虑的重要因素。” 在接种ChAdOx1 nCoV-19 (ChAd) 或BNT162b2 (BNT)疫苗后第0-7天，根据初始接种和加强接种以及接种组，在参与者电子日记中自我报告的局部和全身反应的严重程度有研究比较了阿斯利康和辉瑞疫苗(辉瑞紧接着阿斯利康，阿斯利康接着辉瑞，阿斯利康两次未混合，辉瑞两次未混合)在28天和84天的首剂、加强剂间隔期间的4种首剂、加强剂排列。总共有830名参与者被随机登记，463人被分为4组，其中28天是主要刺激间隔，367

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2021-10-05 howi

#Lancet#

90 0
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2021-05-16 豆芽菜菜

学习

96 0
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2021-05-16 大郎该吃药了

什么骚操作#新冠肺炎#

105 0
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2021-05-16 云飞扬19910907

混用？#新冠肺炎#

121 0
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2021-05-16 goodbing

顶刊就是不一样，质量很高，内容精彩！学到很多

131 0
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2021-05-15 医鸣惊人

认真学习了

94 0
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2021-05-15 病毒猎手

#新冠疫苗#这是首篇疫苗混用的论文！！效果呢？会不会更好，还是好+差=中？

137 0

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