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Sci Rep:电子香烟也会增加罹患癌症的风险!

2017-05-20 MedSci MedSci原创

电子香烟(E-cigs)的设计原理是在电子水烟溶液中递送尼古丁,而不是通过烟雾,也没有烟草燃烧的装置。此前,电子香烟被认为是较传统香烟更安全的替代品,电子香烟作为一种生活方式的选择消费品被允许销售,对其的限制很少,且缺乏监管准则。E-cigs也在不吸烟者和青少年中受到欢迎,成为紧急的公共卫生问题。尽管E-cigs全球消费量不断增长,但其安全性仍然未得到证实,而且这些装置是否会导致癌症的体内毒理学目

电子香烟(E-cigs)的设计原理是在电子水烟溶液中递送尼古丁,而不是通过烟雾,也没有烟草燃烧的装置。

此前,电子香烟被认为是较传统香烟更安全的替代品,电子香烟作为一种生活方式的选择消费品被允许销售,对其的限制很少,且缺乏监管准则。E-cigs也在不吸烟者和青少年中受到欢迎,成为紧急的公共卫生问题。

尽管E-cigs全球消费量不断增长,但其安全性仍然未得到证实,而且这些装置是否会导致癌症的体内毒理学目前尚不清楚。

近期,一项发表在杂志Sci Rep上的研究展示了E-cigs蒸气在大鼠肺模型中的共同诱导和促发癌症作用。

研究者们发现E-cigs对I期致癌物 - 生物活化酶(包括多环芳烃活化剂(PAHs))具有强大的增效作用,并增加氧自由基的产生和DNA氧化成8-羟基-2’-脱氧鸟苷。

此外,研究者们还发现E-cigs不仅能在外周血的染色体水平上损伤DNA,如白细胞中的链断裂和网状细胞中的微核形成,而且还在基因水平如尿液中产生点突变。

此项研究结果表明,接触E-cigs也可能会危及人类健康,特别是在年轻的消费者中。

原始出处:
Canistro D, Vivarelli F, et al. E-cigarettes induce toxicological effects that can raise the cancer risk. Sci Rep. 2017 May 17;7(1):2028. doi: 10.1038/s41598-017-02317-8.

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    2017-05-22 lq0307
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  4. 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content=完全戒烟才是王道, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Sat May 20 20:27:17 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-21 jaysppr

    这种研究有意思

    0

  5. 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content=完全戒烟才是王道, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Sat May 20 20:27:17 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-21 139****5926

    好文章学习了

    0

  6. 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content=完全戒烟才是王道, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Sat May 20 20:27:17 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-21 131****2916

    这个就有点意思了

    0

  7. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Sun May 21 05:42:50 CST 2017, time=2017-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200565, encodeId=d66d2005656f, content=完全戒烟才是人道, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMD639O1rzjHRtgB4JSByeux8IG5aRRia2SHXf2Hjtp3j04qdNicAhRe6Vl8Xuz1wziaP61f5Via0TSPBA/0, createdBy=b7712045828, createdName=风寒倩, createdTime=Sat May 20 21:49:22 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200533, encodeId=48fb20053378, content=完全戒烟才是王道, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Sat May 20 20:27:17 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-21 榄枷檬

    戒烟是最健康的消费方式

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Sun May 21 05:42:50 CST 2017, time=2017-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200565, encodeId=d66d2005656f, content=完全戒烟才是人道, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMD639O1rzjHRtgB4JSByeux8IG5aRRia2SHXf2Hjtp3j04qdNicAhRe6Vl8Xuz1wziaP61f5Via0TSPBA/0, createdBy=b7712045828, createdName=风寒倩, createdTime=Sat May 20 21:49:22 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200533, encodeId=48fb20053378, content=完全戒烟才是王道, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Sat May 20 20:27:17 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-21 changjiu

    戒烟就好了,电子香烟也不安全。

    0

  9. 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content=完全戒烟才是王道, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Sat May 20 20:27:17 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-20 风寒倩

    完全戒烟才是人道

    0

  10. 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    2017-05-20 收获你的美

    完全戒烟才是王道

    0

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