Baidu
map

NEJM:双脚出现严重的跖疣,什么原因?

2017-07-20 MedSci MedSci原创

一位25岁的女性接受了原位心脏移植,她被送到一家整形外科诊所,有4年的双脚广泛疣的病史(小组A)。心脏移植术后7年首次出现病变,导致相当大的疼痛、肿胀和残疾。自移植以来,她一直接受霉酚酸酯和他克莫司的免疫抑制治疗。以前的治疗包括外用水杨酸局部化学消融、局部氟尿嘧啶和二氧化碳激光治疗疣。物理检查发现外生性疣状增生对足底表面的跖骨和足跟双脚地区,与相关的低踏板水肿。这些皮肤疣是由感染人乳头瘤病毒引起的

患者女性,25岁,曾接受原位心脏移植,因双脚出现广泛疣(图A)4年而就诊于一家整形外科诊所。



患者述其双脚疣状物是在心脏移植术后7年首次出现,导致严重的疼痛、肿胀和残疾。自接受心脏移植以来,患者一直接受霉酚酸酯和他克莫司进行免疫抑制治疗。患者曾接受外用水杨酸局部化学消融、局部氟尿嘧啶和二氧化碳激光治疗疣。

体格检查发现外生性疣状增生出现在双脚的足底表面的跖骨和足跟区域,同时伴有足部水肿。这些皮肤疣是由于患者感染了人乳头瘤病毒引起的。

患者接受了积极的减压治疗,然后外用西多福韦治疗3个月,一天两次,不改变患者的免疫抑制治疗方案。在这治疗的3个月内,患者的脚部病变逐渐消失(图B)。最终患者可毫不费力的行走,生活质量也得到提高。


原始出处:

Gehaan F. D’Souza, James E. Zins. Severe Plantar Warts in an Immunocompromised Patient. N Engl J Med 2017; 377:267July 20, 2017DOI: 10.1056/NEJMicm1616238.
本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=224407, encodeId=5d7e22440e72, content=治本才能根治, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0eibMt2kVA8tyZ9I1vbiaLDKInEnXia9RqtXe60nKkF8Fs0pceTHNl4A3POwxezQfkaBqibicHRkoAVs/0, createdBy=c0e61967040, createdName=1e14ec7dm65(暂无匿称), createdTime=Thu Jul 20 22:13:46 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224397, encodeId=753622439e5e, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Jul 20 21:27:47 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224359, encodeId=a570224359c8, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Jul 20 20:14:18 CST 2017, time=2017-07-20, status=1, ipAttribution=)]
    2017-07-20 1e14ec7dm65(暂无匿称)

    治本才能根治

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=224407, encodeId=5d7e22440e72, content=治本才能根治, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0eibMt2kVA8tyZ9I1vbiaLDKInEnXia9RqtXe60nKkF8Fs0pceTHNl4A3POwxezQfkaBqibicHRkoAVs/0, createdBy=c0e61967040, createdName=1e14ec7dm65(暂无匿称), createdTime=Thu Jul 20 22:13:46 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224397, encodeId=753622439e5e, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Jul 20 21:27:47 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224359, encodeId=a570224359c8, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Jul 20 20:14:18 CST 2017, time=2017-07-20, status=1, ipAttribution=)]
    2017-07-20 changjiu

    学习了,谢谢

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=224407, encodeId=5d7e22440e72, content=治本才能根治, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0eibMt2kVA8tyZ9I1vbiaLDKInEnXia9RqtXe60nKkF8Fs0pceTHNl4A3POwxezQfkaBqibicHRkoAVs/0, createdBy=c0e61967040, createdName=1e14ec7dm65(暂无匿称), createdTime=Thu Jul 20 22:13:46 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224397, encodeId=753622439e5e, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Jul 20 21:27:47 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224359, encodeId=a570224359c8, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Jul 20 20:14:18 CST 2017, time=2017-07-20, status=1, ipAttribution=)]
    2017-07-20 184****9840

    学习了受益匪浅

    0

Baidu
map
Baidu
map
Baidu
map